DCC3157 |
Lu-002c |
Novel potent β2c-specific inhibitor, displaying moderate trypanocidal activity |
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DCC3158 |
Lu-002i |
Novel β2i-specific inhibitor, displaying moderate trypanocidal activity |
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DCC3159 |
Lu-aa47070 |
Potent and selective adenosine A2A receptor antagonist |
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DCC3160 |
Lu-af11205 |
Potent mGlu5 receptor positive allosteric modulator (PAM) |
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DCC3161 |
Luf-5764 |
A1 adenosine receptor antagonist |
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DCC3162 |
Luf-6056 |
Human adenosine A1 receptor antagonist |
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DCC3163 |
Luf-6258 |
Hybrid ortho/allosteric ligand of the adenosine A(1) receptor |
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DCC3164 |
Lugdunin |
Thiazolidine-containing cyclic peptide antibiotic, suppressing growth of species of disease-causing bacteria in that part of the human microbiome |
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DCC3165 |
Luminespib Mesylate |
Novel inhibitor of heat shock protein 90 (Hsp90) |
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DCC3166 |
Luminolate (luminol Sodium Salt) |
Immune modulator with SARS-CoV-2 antiviral activity via a multi-target mechanism including localized, self-limiting reactive oxygen species (ROS) scavenging activities that were demonstrated in a model of lipopolysaccharide (LPS)-induced joint inflammatio |
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DCC3167 |
Lx7101 Hydrochloride |
Novel Dual LIM-Kinase and ROCK Inhibitor for the Treatment of Glaucoma |
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DCC3168 |
lxrβ-agonist-19 |
Novel selective LXRβ agonist, reducing total brain Aβ |
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DCC3169 |
Lxy6006 |
Novel Manassantin A Derivative, Inhibiting Hypoxia-Inducible Factor 1 and Tumor Growth |
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DCC3170 |
Lxy6090 |
Novel potent HIF-1 inhibitor, also downregulating the protein level of HIF-1alpha, which depended on von Hippel-Lindau for proteasome degradation, showing in vivo anticancer efficacy by decreasing the HIF-1alpha expression in nude mice bearing MX-1 tumor |
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DCC3171 |
Ly2019-005 |
Novel LRRK2 kinase inhibitor against the wild-type and G2019S mutant LRRK2 kinase being 424.40 ± 1.31 nM, 378.80 ± 1.20 nM, respectively |
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DCC3172 |
Ly2019-006 |
Novel LRRK2 kinase inhibitor against the wild-type and G2019S mutant LRRK2 kinase being 1526.00 ± 0.87 nM, 1165.00 ± 1.18 nM, respectively |
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DCC3173 |
Ly2048978 |
Novel, potent, orally-bioavailable kappa-selective antagonist with activity in animal models predictive of efficacy in mood and addictive disorders |
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DCC3174 |
ly-2121260 |
Novel glucokinase activator (GKA) |
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DCC3175 |
ly-2140023 |
Novel mGlu2/3 receptor agonist; Prodrug of LY-404039 |
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DCC3176 |
Ly-231617 |
Potent antioxidant, being cytoprotective in models of focal and global cerebral ischemia |
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DCC3177 |
Ly2389575 |
Selective negative allosteric modulator of mGlu3 |
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DCC3178 |
Ly-278584 |
Potent 5-HT3 serotonin receptor antagonist |
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DCC3179 |
ly2886721 Hydrochloride |
Orally active cell-permeable inhibitor of human |
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DCC3180 |
Ly2934747 |
Novel, potent, and systemically bioavailable mGlu2/3 receptor agonist, exhibiting both antipsychotic and analgesic properties in vivo |
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DCC3181 |
ly-294002 Hydrochloride |
Selective cell permeable phosphatidylinositol 3-kinase (PI3K) inhibitor |
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DCC3182 |
Ly2979165 Ammonium Salt |
Novel highly potent and selective agonist of metabotropic glutamate (mGlu) receptors 2 and 3 |
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DCC3183 |
Ly-333531 Mesylate |
Potent and selective inhibitor of PKCβI and PKCβII |
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DCC3184 |
Ly339434 |
Potent GluR5 kainate receptor agonist |
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DCC3185 |
Ly382884 |
Selective GluR5 kainate receptor antagonist |
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DCC3186 |
Ly392098 |
AMPA receptor potentiator |
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