| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DCC3367 | Mips1780 | Novel selective positive allosteric modulator (PAM) at the M1 muscarinic acetylcholine receptor |
|
| DCC3368 | Mipsagargin | Novel thapsigargin-based PSMA-activated prodrug, inhibiting the sarcoplasmic/endoplasmic reticulum calcium adenosine triphosphatase (SERCA) pump protein |
|
| DCC3369 | Mir-21 Inhibitor | Novel specific and efficient inhibitor of miR-21 expression, inducing a 485% increase in the luciferase reporter signal at 10 μM |
|
| DCC3370 | Mir-21 Inhibitor-1 | Novel inhibitor of microRNA-21 (miR-21) |
|
| DCC3371 | Miro1 Reducer | Novel Miro1 degrader, rescuing dopaminergic neurodegeneration and promoting Miro1 degradation in Parkinson’s Disease fibroblasts |
|
| DCC3372 | Miro1 Reducer 3 | Novel degrader of Miro1 (mitochondrial Rho GTPase 1), reducing Miro1 levels in fibroblasts and stress-induced degeneration of dopaminergic neurons derived from Parkinson's disease (PD) patients, as well as age-dependent neuronal loss and prolongs lifespan |
|
| DCC3373 | miroistonil | Novel inhibitor of AMA1-RON2 interaction, blocking merozoite invasion from schizont-infected RBCs; Antidepressant; Acetylcholinesterase inhibitor |
|
| DCC3374 | mitf-in-17 | The first small molecule inhibitor of Mitf-E-box DNA binding with depigmenting activity |
|
| DCC3375 | Mitobady | Sensitive and specific Raman probe for live cell imaging of mitochondria |
|
| DCC3376 | Mitodpp-2 | Fluorescent probe for measuring the activity levels of erasers of S-palmitoylation, acyl-protein thioesterases (APTs), within mitochondria of live cells |
|
| DCC3377 | Mitoebselen-2 | Radiation Mitigator, reducing lipid hydroperoxides and preventing apoptotic cell death |
|
| DCC3378 | Mitofp | Novel mitochondrial-targeted pan-APT inhibitor |
|
| DCC3379 | Mito-peg5-ato | Novel potent antiproliferative mitochondria-targeted OXPHOS inhibitor (IC50=38 nM) in MiaPaCa-2 cells, being more effective than other inhibitors of OXPHOS in MiaPaCa-2 and U87MG cells |
|
| DCC3380 | mitopy1 | Novel selective fluorescent H2O2 probe, tracking the mitochondria of live biological specimens and responds to local fluxes of hydrogen peroxide (H2O2) by a turn-on fluorescence enhancement |
|
| DCC3381 | Mitozolomide | Antineoplastic DNA alkylating agent |
|
| DCC3382 | Mizoribine Mono-phosphate | Specific inhibitor of the cellular inosine-5-monophosphate dehydrogenase (IMPDH); Immunosuppressive agent |
|
| DCC3383 | Mk0359 | Potent and selective PDE4 inhibitor |
|
| DCC3384 | Mk-0493 | Novel potent, orally active and selective agonist of the melanocortin receptor 4 (MC4R) |
|
| DCC3385 | mk-0499 | The class III antiarrhythmic agent, blocking HERG, a human cardiac delayed rectifier K+ channel |
|
| DCC3386 | Mk-0626 | Novel Dipeptidyl peptidase IV (DPP-4) inhibitor, improving neovascularization by increasing both the number of circulating endothelial progenitor cells and endothelial nitric oxide synthetase expression |
|
| DCC3387 | Mk-0633 Tosylate | Potent and Selective 5-Lipoxygenase Inhibitor |
|
| DCC3388 | Mk-0736 | Selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor |
|
| DCC3389 | Mk-0916 | Selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor |
|
| DCC3390 | Mk-1220 | Novel Macrocyclic Inhibitor of Hepatitis C Virus NS3/4A Protease with Improved Preclinical Plasma Exposure |
|
| DCC3391 | Mk-1597 | Novel renin inhibitor |
|
| DCC3392 | Mk-2295 | Potent TRPV1 antagonist |
|
| DCC3393 | Mk-386 | Potent and selective human type-1 5alpha-reductase inhibitor |
|
| DCC3394 | Mk-4541 | Novel Selective Androgen Receptor Modulator (SARM) |
|
| DCC3395 | Mk-5046 | Novel nonpeptide bombesin receptor subtype-3 agonist |
|
| DCC3396 | Mk-6884 | Novel potent muscarinic acetylcholine receptor 4 (M4) positive allosteric modulator (PAM) |
|
