| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC9809 | APS-3-77 HCl Featured | APS-3-77 is the negative binder of KSR2. |
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| DC8664 | APTO-253 | APTO-253 is a novel small molecule with potent anti-tumor activity in cancer cells via induction of the gene that expresses the Krüppel-like factor 4 (KLF4) master transcription factor, leading to cell cycle inhibition and programmed cell death. |
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| DC21999 | APTO-253 hydrochloride | APTO-253 is a small molecule inducer of KLF4, stabilizes G-quadruplex DNA and reduces MYC mRNA expression and protein levels. |
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| DC20672 | APX001A Featured | APX001 (APX 001A;E1210) is a novel broad-spectrum antifungal agent that inhibits the fungal protein Gwt1, demonstrates significantly acitive MIC50 and MIC90 values of 0.004 and 0.031 ug/ml (16 strains of C. auris). |
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| DC11809 | APX-115 Featured | APX-115 (Ewha 18278) is a first-in-class, orally active, pan-NADPH oxidase (Nox) inhibitor with Ki of 1.08, 0.57, 0.63 nM for Nox1, Nox2, and Nox4, respectively. |
|
| DC11194 | APX2009 | APX2009 (APX-2009) is a novel potent inhibitor of reduction-oxidation factor 1-apurinic/apyrimidinic endonuclease 1 (Ref-1/APE1) with IC50 of 0.45 uM for redox EMSA inhibition. |
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| DC11195 | APX2014 | APX2014 (APX-2014) is a novel potent inhibitor of reduction-oxidation factor 1-apurinic/apyrimidinic endonuclease 1 (Ref-1/APE1) with IC50 of 0.2 uM for redox EMSA inhibition. |
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| DC7922 | APY0201 Featured | APY0201 is a potent, highly selective PIKfyve kinase inhibitor. |
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| DC7358 | APY29 Featured | APY29 is an allosteric modulator of IRE1α; inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity. |
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| DC23311 | AQ-101 | AQ-101 is a novel small-molecule anthraquinone analog that induces MDM2 protein degradation (Kd=0.37 uM) through a self-ubiquitination and proteasome-mediated mechanism, leading to activation of p53. |
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| DC12155 | AQ-13 dihydrochloride | AQ-13 dihydrochloride is an aminoquinoline antimalarial drug that is effective against chloroquine-resistant strains of Plasmodium falciparum. |
|
| DC20673 | AQW-051 | AQW-051 is a novel, potent and selective, orally bioavailable, brain-penetrant α7 nAChR partial agonist with pKd of 7.56. |
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| DC23139 | AQX 1125 | AQX 1125 (Rosiptor) is a specific, orally bioavailable SHIP1 activator. |
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| DC20674 | AR03 | AR03 (AR-03, AR 03, Ape1 repair inhibitor 03) is a novel small molecule inhibitor of DNA repair protein apurinic/apyrimidinic endonuclease 1 (APE1) endonuclease activity with IC50 of 5 uM. |
|
| DC8764 | AR 231453 Featured | AR231453 is a potent and selective small molecule agonist of GPR119 that enhances glucose-dependent insulin secretion and glucagon-like peptide 1 (GLP-1) release; Antidiabetic agent. |
|
| DC10135 | AR-7 Featured | AR7 is a retinoic acid receptor α (RARα) antagonist. |
|
| DC22493 | ARA-290(Cibinetide) Featured | ARA-290 (Cibinetide) is a non-erythropoietic erythropoietin (EPO) derivative. |
|
| DC8888 | Ara-G Featured | Ara-G (9-β-D-Arabinofuranosyl guanine) is an inducer of apoptosis, inhibitor of DNA synthesis, an antimetabolite, and antineoplastic. |
|
| DCAPI1051 | Arbidol HCl (Umifenovir) Featured | Umifenovir is currently being investigated as a potential treatment and prophylactic agent for COVID-19 caused by SARS-CoV2 infections in combination with both currently available and investigational HIV therapies. Arbidol hydrochloride (Umifenovir hydroc |
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| DC20675 | AR-C102222 | AR-C102222 is a potent, selective iNOS inhibitor with IC50 of 35 nM, dislapys 3,000-fold and 20-fold selectivity over eNOS and nNOS respectively. |
|
| DC22544 | AR-C155858 | AR-C155858 is a potent monocarboxylate transporter MCT1 and MCT2 with Ki of 2.3 nM and <10 nM, displays no activity at MCT4. |
|
| DC20265 | Arctigenin Featured | Arctigenin is an extract from A. lappa, a burdock plant traditionally used in Japanese Kampo medicine for its antioxidant, anti-inflammatory, |
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| DC9659 | Arctiin(NSC 315527) Featured | Arctiin, a plant lignan that can be extracted from the Arctium lappa (burdock) seeds, is a possible environmental endocrine disruptor compounds and have been shown to influence sex hormone metabolism as well as protein synthesis, steroid biosynthesis. |
|
| DC12359 | Arg-AMS | Arg-AMS is a potent nanomolar inhibitor of arginyl tRNA synthetase, which displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes. |
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| DCAPI1329 | Argatroban Featured | Argatroban |
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| DC8841 | Argatroban monohydrate Featured | Argatroban monohydrate is a direct, selective thrombin inhibitor. |
|
| DC9487 | Arg-Gly-Asp-Ser Featured | Arg-Gly-Asp-Ser(RGDS peptide) is an integrin binding sequence that inhibits integrin receptor function; decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS |
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| DC9645 | (+)-Arglabin Featured | Arglabin is a sesquiterpene gamma-lactone is isolated from Artemisia glabella; anticancer natural compound. |
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| DC23605 | AR-HO47108 | AR-HO47108 is a potent, selective acid pump antagonist (potassium-competitive acid blocker or P-CAB) that reversiblely inhibits gastric H+/K+-ATPase with pIC50 of 7.0. |
|
| DC9147 | Aripiprazole | Aripiprazole(Abilify) is a human 5-HT1A receptor partial agonist with a Ki of 4.2 nM. |
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