| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC10110 | ARM390 Hydrochloride Featured | ARM390 is a non-peptidic, low-internalizing δ-selective opioid receptor agonist. |
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| DC20677 | ARN 077 | ARN077 is the first potent, selective N-acylethanolamine acid amidase (NAAA) inhibitor with IC50 of 7 nM on both rat NAAA and human NAAA. |
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| DC12569 | ARN14494 | ARN14494 (ARN-14494) is a potent, small molecule serine palmitoyltransferase (SPT) inhibitor with IC50 of 27.3 nM. |
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| DC22000 | ARN19874 | ARN19874 (ARN-19874) is the first selective, cell-active inhibitor of N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) with IC50 of 33.7 uM. |
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| DC9345 | ARN2966(2-PMAP) Featured | ARN2966 is a potent post-transcriptional modulator of APP expression; reduces expression of APP with resultant lower production of Aβ. |
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| DC10824 | ARN-3236 Featured | ARN-3236 is potent, orally active and selective SIK2 inhibitor. ARN-3236 inhibited the growth of 10 ovarian cancer cell lines at an IC50 of 0.8 to 2.6 μmol/L. |
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| DC20676 | ARN-3261 | ARN-3261 is a potent, selective, orally available salt inducible kinase SIK2 and SIK3 inhibitor with IC50 of 11 nM and 19 nM, respectively. |
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| DC7064 | Apalutamide（ARN509） Featured | ARN-509 is a selective and competitive androgen receptor inhibitor with IC50 of 16 nM, useful for prostate cancer treatment. |
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| DC20678 | ARN 726 | ARN726 is a potent, selective, orally bioavailable N-acylethanolamine acid amidase (NAAA) inhibitor with IC50 of 63 nM (r-NAAA) and 27 nM (h-NAAA). |
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| DC12460 | ARP101 | ARP101 (ARP-101) is a selective MMP-2 inhibitor, induces autophagy-associated cell death in cancer cells. |
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| DC9972 | ARQ-092(Miransertib) Featured | ARQ 092 is an oral activie, potent and selective AKT inhibitor with IC50 values: 5.0 nM (AKT1); 4.5 nM (AKT2); 16 nM (AKT3). |
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| DC7820 | ARQ 621 Featured | ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1. |
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| DC10975 | ARQ-531 Featured | ARQ-531 is a potent, reversible, orally available inhibitor of both wild type and C481S-mutant BTK kinase with IC50 of 0.85 and 0.39 nM, |
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| DC8486 | Varlitinib(ARRY-334543) | ARRY-334543 is a small molecule inhibitor of ErbB1 and ErbB2 tyrosine kinases. |
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| DC20679 | ARRY-502 | ARRY-502 is an orally bioavailable, potent and selective antagonist of the prostaglandin D2 receptor (CRTh2) for treatment of mild to moderate Th2-driven asthma.. |
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| DC8181 | Filanesib(ARRY-520) Featured | ARRY-520 is a synthetic, small molecule kinesin spindle protein (KSP) inhibitor with IC50 of 6 nM. |
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| DC9495 | ARRY-520 (R enantiomer) | ARRY-520 R enantiomer is the R form of ARRY-520, which is a synthetic, small molecule kinesin spindle protein (KSP) inhibitor with IC50 of 6 nM. |
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| DC10738 | ARS-1323 Featured | ARS-1323 is a novel inhibitor of mutant K-ras G12C. |
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| DC10725 | ARS-1620 Featured | ARS-1620 is a covalent compound with high potency and selectivity for KRAS-G12C. |
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| DC12031 | ARS-1630 Featured | ARS-1630 is the R-conformational atropisomer of ARS-1620, 1,000-fold less potent than ARS-1620 (1.2 ± 0.6 M-1s-1) and thus acts as a unique inactive control compound.. |
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| DC8816 | ARS-853 Featured | ARS-853 is a selective, covalent inhibitor of KRAS-G12C that inhibits mutant KRAS driven signaling by binding to the GDP bound oncoprotein and preventing activation. |
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| DC21452 | Artefenomel | Artefenomel (OZ439) is a novel, next-generation antimalarial ozonide that demonstrates high potentcy against P. falciparum in vitro and P. berghei in vivo (K1/NF54, IC50=2.0/3.2 nM).. |
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| DC21451 | Arterolane | Arterolane (OZ277. |
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| DCAPI1125 | Articaine HCl | Articaine is a dental local anesthetic which contains an additional ester group that is metabolized by estearases in blood and tissue. |
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| DC10334 | ARV-771 Featured | ARV-771 is a potent bromodomain and extra-terminal (BET) proteins degrader with Kd values of 4.7, 7.6, 7.6 nM against bromodomain 2, 3 and 4, respectively. |
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| DC12024 | ARV-825 Featured | ARV-825 is a BRD4 Inhibitor based on PROTAC technology. ARV-825 binds to BD1 and BD2 of BRD4 with Kds of 90 and 28 nM, respectively. |
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| DC12614 | Arylsulfonamide 64B | Arylsulfonamide 64B (HIF inhibitor 64B) is a small molecule HIF pathway inhibitor, blocks hypoxia-induced expression of c-Met and CXCR4 and uveal melanoma (UM) cell migration. |
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| DC20687 | AS 2553627 | AS 2553627 (AS2553627) is a novel potent, selective pan-JAK inhibitor with IC50 of 0.46, 0.30, 0.14 and 2.0 nM for JAK1, JAK2, JAK3 and TYK2, respectively. |
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| DC8256 | AS 602801(Bentamapimod) Featured | AS 602801(Bentamapimod) is a novel, orally active inhibitor of JNK. |
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| DC9840 | AS-8351 Featured | AS 8351 induces reprogramming of human fetal lung fibroblasts into functional cardiomyocytes, in combination with CHIR 99021, A83-01, BIX 01294, SC1, Y-27632, OAC2, SU 16f and JNJ 10198409. |
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