| DC66384 |
WAY-658675
Featured
|
WAY-658675 is an active molecule. |
|
| DC66385 |
WAY-659873
Featured
|
WAY-659873 is an active molecule. |
|
| DC66386 |
WAY-660222
Featured
|
WAY-660222 is an active molecule. |
|
| DC66387 |
WAY-324572
Featured
|
WAY-324572 is an active molecule. |
|
| DC66388 |
WAY-639228
Featured
|
WAY-639228-A is an active molecule. |
|
| DC66389 |
WAY-620521
Featured
|
WAY-620521 is an active molecule. |
|
| DC66390 |
WAY-607695
Featured
|
WAY-607695 is an active molecule. |
|
| DC66391 |
Nurr1 agonist 7
Featured
|
Nurr1 agonist 7 (compound 110) is a Nurr1 agonist with an EC50 value of 0.12 μM. |
|
| DC66392 |
Nurr1 agonist 8
Featured
|
Nurr1 agonist 8 (compound 111) is a Nurr1 agonist with an EC50 value of 0.09 μM. |
|
| DC66393 |
WAY-221060
Featured
|
WAY-221060-A is an active molecule. |
|
| DC66394 |
Anti-inflammatory agent 63
Featured
|
Anti-inflammatory agent 63 is an anti-inflammatory agent that shows optimal inhibitory activity (EC50 = 5.33±0.57 μM) against the production of nitric oxide (NO) induced by lipopolysaccharide (LPS) in RAW264.7 cells. |
|
| DC66395 |
WAY-639872
Featured
|
WAY-639872 is an active molecule. |
|
| DC66396 |
WAY-215718
Featured
|
WAY-215718 is an active molecule. |
|
| DC66397 |
WAY-328127
Featured
|
WAY-328127 is an active molecule. |
|
| DC66398 |
WAY-616296
Featured
|
WAY-616296 is an active molecule. |
|
| DC66399 |
WAY-325811
Featured
|
WAY-325811 is an active molecule. |
|
| DC66400 |
WAY-649123
Featured
|
WAY-649123 is an active molecule. |
|
| DC66401 |
Tyrosinase-IN-17
Featured
|
Tyrosinase-IN-17 (Compound 5b) is a lipophilic, skin-permeable, and non-cytotoxic Tyrosinase inhibitor (pIC50=4.99). Tyrosinase-IN-17 can be used for research on melanin-related diseases, such as melanoma, melanogenesis, etc. |
|
| DC66402 |
Aβ42 agonist-1
Featured
|
Aβ42 agonist-1 (compound 7a) is a small molecule compound that can promote Aβ42 aggregation. Aβ42 agonist-1 can interact with Aβ42 oligomers and pentamers to promote nontoxic aggregate self-assembly and rapid fibril formation. Aβ42 agonist-1 prevents Aβ42-induced cytotoxicity in HT22 hippocampal neuronal cells. |
|
| DC66403 |
Aurora kinase inhibitor-11
Featured
|
Aurora kinase inhibitor-11 (compound 25) is an inhibitor of Aurora Kinase with an IC50 of 0.14 μM. Aurora kinase inhibitor-11 has anticancer activity. |
|
| DC66404 |
Aβ42 agonist-2
Featured
|
Aβ42 agonist-2 (compound 7b) is a small molecule compound that can promote Aβ42 aggregation. Aβ42 agonist-2 can interact with Aβ42 oligomers and pentamers to promote nontoxic aggregate self-assembly and rapid fibril formation. Aβ42 agonist-2 prevents Aβ42-induced cytotoxicity in HT22 hippocampal neuronal cells. |
|
| DC66405 |
ATG12-ATG3 inhibitor 1
Featured
|
ATG12-ATG3 inhibitor 1 (compound 189) is a potent inhibitor of autophage. |
|
| DC66406 |
hCAI/II-IN-7
Featured
|
hCAI/II-IN-7 (compound 1F) is a potent carbonic anhydrase (CA) inhibitor with Ki values of 23 nM, 44 nM and 20.57 µM for hCA-I, hCA-II and bovine CA, respectively. |
|
| DC66407 |
HDAC6-IN-27
Featured
|
HDAC6-IN-27 (compound 8C) is a HDAC inhibitor with IC50 vales of 15.9 nM 136.5 nM and 6180.2 nM for HDAC6, HDAC8 and HDAC1, respectively. HDAC6-IN-27 shows potent antiparasitic effects. |
|
| DC66408 |
AN-12-H5 intermediate-3
Featured
|
AN-12-H5 intermediate-3 is an intermediate of the viral inhibitor AN-12-H5 (HY-120900) and can be used to synthesize Antibody-Drug Conjugates (ADCs). |
|
| DC66409 |
Anti-osteoporosis agent-6
Featured
|
Anti-osteoporosis agent-6 (compound 174) is an anti-osteoporosis agent. Anti-osteoporosis agent-6 has 14.11% inhibition rate against osteoclast formation at 10 μM. |
|
| DC66410 |
Anti-osteoporosis agent-5
Featured
|
Anti-osteoporosis agent-5 (compound 189) is a potent inhibitor of the formation of osteoclasts. |
|
| DC66411 |
2',4',6',4-tetramethoxychalcone
Featured
|
4,2′,4′,6′-Tetramethoxychalcone is a flavonoids that can be isolated from Gnaphalium affine. |
|
| DC66412 |
Senexin A hydrochloride
Featured
|
Senexin A hydrochloride is an inhibitor of CDK8/19 (IC50: 280 nM, CDK8) and an inhibitor downstream of p21 transcription. It only inhibits p21-induced transcription but does not inhibit other biological effects of p21. Senexin A hydrochloride inhibits CMV-GFP induction as well as the p21 stimulatory activity of the consensus NF-κB-dependent promoters. |
|
| DC66413 |
TEAD-IN-8
Featured
|
TEAD-IN-8 is a novel TEAD inhibitor, which potently and specifically inhibits TEAD-YAP transcriptional activities. TM2, alone or in combination with MEK inhibitors, exhibits potent antiproliferative effects in YAP-dependent cancer cells. |
|
