| DC10926 |
LY900009
Featured
|
LY900009 (LY-900009) is an orally active small molecule inhibitor of Notch signalling via selective inhibition of the γ-secretase protein. |
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| DC23020 |
Lycobetaine（Ungeremine）
Featured
|
Lycobetaine（Ungeremine） is a potential biofungicide against Penicillium roqueforti and Aspergillus niger. |
|
| DC10715 |
LYN-1604
Featured
|
LYN-1604 is a potential ULK1 agonist with IC50 of 1.66 μM against MDA-MB-231 cells and it binds to wild-type ULK1 with a binding affinity in the nanomole range (Kd=291.4 nM). |
|
| DC24081 |
Lyn-IN-1 (Synonyms: Bafetinib analog)
Featured
|
Lyn-IN-1 is a potent and selective dual Bcr-Abl/Lyn inhibitor.. |
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| DC20440 |
LYPLAL1-IN-11 |
LYPLAL1-IN-11 is a potent, selective, covalent inhibitor of lysophospholipase-like 1 (LYPLAL1) with IC50 of 6 nM. |
|
| DC10358 |
Lys01 trihydrochloride
Featured
|
Lys01 trihydrochloride (Lys05) is a novel lysosomal autophagy inhibitor with IC50 values of 3.6, 3.8, 6 and 7.9 μM for 1205Lu, c8161, LN229 and HT-29 cell line in the MTT assay. |
|
| DC10508 |
Lys05
Featured
|
Lys05 is a new lysosomal autophagy inhibitor which potently accumulates within and deacidifies the lysosome of both cells and tumors, resulting in sustained inhibition of autophagy and tumor growth. |
|
| DC21262 |
LYS228 |
LYS228 is a novel potent monobactam that shows potent activity against carbapenem-resistant isolates of Enterobacteriaceae with MIC90 of 2 ug/ml. |
|
| DC11106 |
Vafidemstat (ORY-2001)
Featured
|
Vafidemstat (ORY-2001) is an oral, brain penetrant drug that inhibits LSD1 and MAOB by reducing cognitive impairment, including memory loss and neuroinflammation. It also has neuroprotective effects. |
|
| DC12235 |
LysoPC(14:0/0:0) |
LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. |
|
| DC23382 |
L-α-Hydroxyglutaric acid disodium salt |
L-α-Hydroxyglutaric acid disodium salt (L-2-Hydroxyglutarate. |
|
| DC8478 |
M 344
Featured
|
M 344 enhances the sensitivity of human squamous carcinoma cells to radiation and promotes cell cycle arrest and apoptosis in human endometrial cancer and ovarian cancer cells (ED50 = 2.3 μM). |
|
| DC22728 |
M-110 |
M-110 is a potent, selective inhibitor of PIM kinase family with preference for PIM-3 with IC50 of 0.047, 2.5 and 2.5 uM for PIM3, PIM1 and PIM2, respectively. |
|
| DC10751 |
M2698
Featured
|
M2698 is a potent dual-inhibitor of p70S6K and Akt that affects tumor growth in mouse models of cancer and crosses the blood-brain barrier. |
|
| DC21264 |
M4284 |
M4284 (M-4284) is a high-affinity biphenyl mannoside FimH inhibitor with HAI of 16 nM in hemagglutination assay. |
|
| DC21265 |
M-525 |
M-525 is a first-in-class, highly potent, irreversible small-molecule inhibitor of the menin-MLL interaction with binding IC50 of 3.3 nM in FP assays. |
|
| DC12034 |
MA-0204
Featured
|
MA-0204 is a potent, selective PPARδ modulator with good pharmacokinetic properties. |
|
| DC21339 |
MAC1 |
MAC1 (Monastrol Antagonizing Compound 1) is a small molecule that can rescue spindle bipolarity in cells lacking Eg5 activity. |
|
| DC21266 |
MAC13772 |
MAC13772 is a potent inhibitor of BioA with an IC50 of 250 nM, a novel antibacterial inhibitor that selectively inhibits PABA biosynthesis in M tuberculosis.. |
|
| DC21267 |
MAC168425 |
MAC168425 is a novel antibacterial inhibitor that interferes with glycine metabolism in E coli.. |
|
| DC21268 |
MAC173979 |
MAC173979 is a novel time-dependent inhibitor of p-aminobenzoic acid biosynthesis with IC50 of 30 uM, represents the first PABA biosynthesis inhibitor with activity against Gram-negative bacteria.. |
|
| DC20269 |
mAChR-IN-1
Featured
|
mAChR-IN-1 is a potent muscarinic cholinergic receptor(mAChR) antagonist with IC50 of 17 nM.. |
|
| DC1012 |
Macitentan (Actelion-1,ACT-064992)
Featured
|
macitentan (Actelion-1, ACT-064992) is an orally active, non-peptide dual endothelin (ET)A/B receptor antagonist with IC50 of 0.5 nM/391 nM. |
|
| DC9922 |
Macranthoidin B |
Macranthoidin B is a major bioactive saponin in rat plasma after oral administration of extraction of saponins from Flos Lonicerae. |
|
| DC9741 |
Mad2 inhibitor-1 (M2I-1)
Featured
|
Mad2 Inhibitor-1 (M2I-1) is a small molecule protein-protein interaction inhibitor targeting the mitotic spindle assembly checkpoint. |
|
| DC9693 |
Madrasin
Featured
|
Madrasin inhibits pre-mRNA splicing in vitro and modify splicing of endogenous pre-mRNA. |
|
| DC8125 |
ETH 4030(Magnesium ionophore III)
Featured
|
Magnesium ionophore III is an onophore used in solvent polymeric membrane electrodes for the assay of Mg2+ activities in blood serum in vitro. |
|
| DC11215 |
MAI-150 |
MAI-150 is a peptidomimetic inhibitor of APC-Asef interaction, blocks colorectal cancer migration.. |
|
| DC11201 |
MAI-400 |
MAI-400 (MAI400) is a novel peptide inhibitor of APC-Asef interaction with Kd of 12 nM and IC50 of 0.25 uM. |
|
| DC10560 |
MAK683
Featured
|
MAK683 is a novel PRC2/EED inhibitor. |
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