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Cat. No. Product Name Field of Application Chemical Structure
DC10926 LY900009 Featured LY900009 (LY-900009) is an orally active small molecule inhibitor of Notch signalling via selective inhibition of the γ-secretase protein.
DC23020 Lycobetaine(Ungeremine) Featured Lycobetaine(Ungeremine) is a potential biofungicide against Penicillium roqueforti and Aspergillus niger.
DC10715 LYN-1604 Featured LYN-1604 is a potential ULK1 agonist with IC50 of 1.66 μM against MDA-MB-231 cells and it binds to wild-type ULK1 with a binding affinity in the nanomole range (Kd=291.4 nM).
DC24081 Lyn-IN-1 (Synonyms: Bafetinib analog) Featured Lyn-IN-1 is a potent and selective dual Bcr-Abl/Lyn inhibitor..
DC20440 LYPLAL1-IN-11 LYPLAL1-IN-11 is a potent, selective, covalent inhibitor of lysophospholipase-like 1 (LYPLAL1) with IC50 of 6 nM.
DC10358 Lys01 trihydrochloride Featured Lys01 trihydrochloride (Lys05) is a novel lysosomal autophagy inhibitor with IC50 values of 3.6, 3.8, 6 and 7.9 μM for 1205Lu, c8161, LN229 and HT-29 cell line in the MTT assay.
DC10508 Lys05 Featured Lys05 is a new lysosomal autophagy inhibitor which potently accumulates within and deacidifies the lysosome of both cells and tumors, resulting in sustained inhibition of autophagy and tumor growth.
DC21262 LYS228 LYS228 is a novel potent monobactam that shows potent activity against carbapenem-resistant isolates of Enterobacteriaceae with MIC90 of 2 ug/ml.
DC11106 Vafidemstat (ORY-2001) Featured Vafidemstat (ORY-2001) is an oral, brain penetrant drug that inhibits LSD1 and MAOB by reducing cognitive impairment, including memory loss and neuroinflammation. It also has neuroprotective effects.
DC12235 LysoPC(14:0/0:0) LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site.
DC23382 L-α-Hydroxyglutaric acid disodium salt L-α-Hydroxyglutaric acid disodium salt (L-2-Hydroxyglutarate.
DC8478 M 344 Featured M 344 enhances the sensitivity of human squamous carcinoma cells to radiation and promotes cell cycle arrest and apoptosis in human endometrial cancer and ovarian cancer cells (ED50 = 2.3 μM).
DC22728 M-110 M-110 is a potent, selective inhibitor of PIM kinase family with preference for PIM-3 with IC50 of 0.047, 2.5 and 2.5 uM for PIM3, PIM1 and PIM2, respectively.
DC10751 M2698 Featured M2698 is a potent dual-inhibitor of p70S6K and Akt that affects tumor growth in mouse models of cancer and crosses the blood-brain barrier.
DC21264 M4284 M4284 (M-4284) is a high-affinity biphenyl mannoside FimH inhibitor with HAI of 16 nM in hemagglutination assay.
DC21265 M-525 M-525 is a first-in-class, highly potent, irreversible small-molecule inhibitor of the menin-MLL interaction with binding IC50 of 3.3 nM in FP assays.
DC12034 MA-0204 Featured MA-0204 is a potent, selective PPARδ modulator with good pharmacokinetic properties.
DC21339 MAC1 MAC1 (Monastrol Antagonizing Compound 1) is a small molecule that can rescue spindle bipolarity in cells lacking Eg5 activity.
DC21266 MAC13772 MAC13772 is a potent inhibitor of BioA with an IC50 of 250 nM, a novel antibacterial inhibitor that selectively inhibits PABA biosynthesis in M tuberculosis..
DC21267 MAC168425 MAC168425 is a novel antibacterial inhibitor that interferes with glycine metabolism in E coli..
DC21268 MAC173979 MAC173979 is a novel time-dependent inhibitor of p-aminobenzoic acid biosynthesis with IC50 of 30 uM, represents the first PABA biosynthesis inhibitor with activity against Gram-negative bacteria..
DC20269 mAChR-IN-1 Featured mAChR-IN-1 is a potent muscarinic cholinergic receptor(mAChR) antagonist with IC50 of 17 nM..
DC1012 Macitentan (Actelion-1,ACT-064992) Featured macitentan (Actelion-1, ACT-064992) is an orally active, non-peptide dual endothelin (ET)A/B receptor antagonist with IC50 of 0.5 nM/391 nM.
DC9922 Macranthoidin B Macranthoidin B is a major bioactive saponin in rat plasma after oral administration of extraction of saponins from Flos Lonicerae.
DC9741 Mad2 inhibitor-1 (M2I-1) Featured Mad2 Inhibitor-1 (M2I-1) is a small molecule protein-protein interaction inhibitor targeting the mitotic spindle assembly checkpoint.
DC9693 Madrasin Featured Madrasin inhibits pre-mRNA splicing in vitro and modify splicing of endogenous pre-mRNA.
DC8125 ETH 4030(Magnesium ionophore III) Featured Magnesium ionophore III is an onophore used in solvent polymeric membrane electrodes for the assay of Mg2+ activities in blood serum in vitro.
DC11215 MAI-150 MAI-150 is a peptidomimetic inhibitor of APC-Asef interaction, blocks colorectal cancer migration..
DC11201 MAI-400 MAI-400 (MAI400) is a novel peptide inhibitor of APC-Asef interaction with Kd of 12 nM and IC50 of 0.25 uM.
DC10560 MAK683 Featured MAK683 is a novel PRC2/EED inhibitor.

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