MAO-IN-M30 dihydrochloride

  Cat. No.:  DC40463   Featured
Chemical Structure
64821-19-8
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Field of application
MAO-IN-M30 dihydrochloride is an orally active, brain-permeable, and brain selective irreversible MAO-A (IC50=37 nM) and MAO-B (IC50=57 nM) inhibitor. MAO-IN-M30 dihydrochloride is a potent iron chelator and radical scavenger. MAO-IN-M30 dihydrochloride has a neuroprotective effect against Dexamethasone-induced brain cell apoptosis. MAO-IN-M30 dihydrochloride also exhibits neurorestorative activity in post MPTP and lactacystin models of Parkinson's disease.
Cas No.: 64821-19-8
Chemical Name: M 30 Dihydrochloride
Synonyms: 5-[N-methyl-N-propargylaminomethyl]-8-hydroxyquinoline dihydrochloride;M-30 dihydrochloride;VAR10300 dihydrochloride;MAO-IN-M30 dihydrochloride;M30 (dihydrochloride);M 30 dihydrochloride;M30 dihydrochloride, >=98% (HPLC);5-[[methyl(prop-2-ynyl)amino]methyl]quinolin-8-ol;dihydrochloride;5-((Methyl(prop-2-yn-1-yl)amino)methyl)quinolin-8-ol dihydrochloride;5-[[Methyl(2-propyn-1-yl)amino]methyl]-8-quinolinol Dihydrochloride;N-(8-Hydroxy-5-quinolylmethyl)-N-methyl-2-propynylamine dihydrochloride;5-{[Methyl(prop-2-yn-1-yl)amino]methyl}quinolin-8-ol--hydrogen chloride ;G14095;5-{[Methyl(prop-2-yn-1-yl)amino]methyl}quinolin-8-ol--hydrogen chloride (1/2);CS-0120810;DA-65172;AKOS040756190;HY-131036;MS-24301;64821-19-8;DTXSID10746624;MAO-IN-M30 (dihydrochloride)
SMILES: Cl.Cl.OC1=CC=C(C2=CC=CN=C21)CN(C)CC#C
Formula: C14H16Cl2N2O
M.Wt: 299.195641517639
Purity: >98%
Sotrage: Please store the product under the recommended conditions in the Certificate of Analysis.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC72911 CHBO4 CHBO4 is a potent, reversible, competitive, and selective hMAO-B inhibitor with an IC50 value of 0.031 μM in CHBO subseries and an Ki value of 0.010 ± 0.005 μM. CHBO4 reduce cell damage by scavenging intracellular reactive oxygen species (ROS). CHBO4 can be used for Parkinson's Disease (PD) research.
DC40463 MAO-IN-M30 dihydrochloride MAO-IN-M30 dihydrochloride is an orally active, brain-permeable, and brain selective irreversible MAO-A (IC50=37 nM) and MAO-B (IC50=57 nM) inhibitor. MAO-IN-M30 dihydrochloride is a potent iron chelator and radical scavenger. MAO-IN-M30 dihydrochloride has a neuroprotective effect against Dexamethasone-induced brain cell apoptosis. MAO-IN-M30 dihydrochloride also exhibits neurorestorative activity in post MPTP and lactacystin models of Parkinson's disease.
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