CHBO4

  Cat. No.:  DC72911   Featured
Chemical Structure
98991-32-3
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Field of application
CHBO4 is a potent, reversible, competitive, and selective hMAO-B inhibitor with an IC50 value of 0.031 μM in CHBO subseries and an Ki value of 0.010 ± 0.005 μM. CHBO4 reduce cell damage by scavenging intracellular reactive oxygen species (ROS). CHBO4 can be used for Parkinson's Disease (PD) research.
Cas No.: 98991-32-3
Chemical Name: 2-Propen-1-one, 1-(4-bromophenyl)-3-(4-fluorophenyl)-
Synonyms: 2-Propen-1-one, 1-(4-bromophenyl)-3-(4-fluorophenyl)-;1-(4-bromophenyl)-3-(4-fluorophenyl)prop-2-en-1-one;4-FLUORO-4'-BROMOCHALCONE
SMILES: BrC1C=CC(C(=O)/C=C/C2C=CC(F)=CC=2)=CC=1
Formula: C15H10OFBr
M.Wt: 305.1417
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
Cat. No. Product name Field of application
DC72911 CHBO4 CHBO4 is a potent, reversible, competitive, and selective hMAO-B inhibitor with an IC50 value of 0.031 μM in CHBO subseries and an Ki value of 0.010 ± 0.005 μM. CHBO4 reduce cell damage by scavenging intracellular reactive oxygen species (ROS). CHBO4 can be used for Parkinson's Disease (PD) research.
DC40463 MAO-IN-M30 dihydrochloride MAO-IN-M30 dihydrochloride is an orally active, brain-permeable, and brain selective irreversible MAO-A (IC50=37 nM) and MAO-B (IC50=57 nM) inhibitor. MAO-IN-M30 dihydrochloride is a potent iron chelator and radical scavenger. MAO-IN-M30 dihydrochloride has a neuroprotective effect against Dexamethasone-induced brain cell apoptosis. MAO-IN-M30 dihydrochloride also exhibits neurorestorative activity in post MPTP and lactacystin models of Parkinson's disease.
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