SNAP 94847 hydrochloride | MCHR1 Antagonist

Cas No.:	1781934-47-1
Chemical Name:	SNAP 94847 hydrochloride
Synonyms:	SNAP 94847 hydrochloride;SNAP 94847 (hydrochloride);SNAP 94847;N-[3-[1-[[4-(3,4-DIFLUOROPHENOXY)PHENYL]METHYL]-4-PIPERIDINYL]-4-METHYLPHENYL]-2-METHYLPROPANAMIDE HYDROCHLORIDE;N-(3-(1-(4-(3,4-Difluorophenoxy)benzyl)piperidin-4-yl)-4-methylphenyl)isobutyramide hydrochloride;N-[3-[1-[[4-(3,4-Difluorophenoxy)phenyl]methyl]-4-piperidinyl]-4-methylphenyl]-2-methylpropanamidehydrochloride;EX-A3588;DA-57950;N-[3-[1-[[4-(3,4-difluorophenoxy)phenyl]methyl]piperidin-4-yl]-4-methylphenyl]-2-methylpropanamide;hydrochloride;MS-29566;SNAP-94847 hydrochloride?;1781934-47-1;N-(3-(1-(4-(3,4-Difluorophenoxy)benzyl)piperidin-4-yl)-4-methylphenyl)isobutyramidehydrochloride;N-[3-(1-{[4-(3,4-difluorophenoxy)phenyl]methyl}piperidin-4-yl)-4-methylphenyl]-2-methylpropanamide hydrochloride;HY-107625A;AKOS024457569;CS-0109085;G13878
SMILES:	Cl[H].FC1=C(C=CC(=C1)OC1C=CC(=CC=1)CN1CCC(C2C=C(C=CC=2C)NC(C(C)C)=O)CC1)F
Formula:	C₂₉H₃₃ClF₂N₂O₂
M.Wt:	515.0343
Purity:	98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

COA

Cat. No.	Product name	Field of application
DC43987	MCHR1 antagonist 2	MCHR1 antagonist 2 is an antagonist of melanin concentrating hormone receptor 1, with an IC50 of 65 nM; MCHR1 antagonist 2 also inhibits hERG, with an IC50 of 4.0 nM in IMR-32 cells.
DC28204	SNAP 94847 hydrochloride	SNAP 94847 hydrochloride is a novel, high affinity selective melanin-concentrating hormonereceptor1 (MCHR1) antagonist with (Ki= 2.2 nM, Kd=530 pM), it displays >80-fold and >500-fold selectivity over MCHα1A and MCHD2 receptors respectively. SNAP 94847 hydrochloride binds with high affinity to the mouse and rat MCHR1 with minimal cross-reactivity to other GPCR, ion channels, enzymes, and transporters.