MCHR1 antagonist 2|CAS 863115-70-2|DC Chemicals

Cas No.:	863115-70-2
Chemical Name:	MCHr1 antagonist 2
Synonyms:	MCHr1 antagonist 2;N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-6-fluoro-4-oxochromene-2-carboxamide;n-(1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl)-6-fluoro-4-oxochromene-2-carboxamide;BCP33948;BDBM50197113;N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-6-fluoro-4-oxo-4H-chromene-2-carboxamide;N-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-yl)-6-fluoro-4-oxo-4H-chromene-2-carboxamide;MCHR1 antagonist 2;N-[1-(1,3-Benzodioxol-5-ylmethyl)-4-piperidinyl]-6-fluoro-4-oxo-4H-1-benzopyran-2-carboxamide (ACI)
SMILES:	O=C1C2C(=CC=C(C=2)F)OC(C(NC2CCN(CC3C=C4C(OCO4)=CC=3)CC2)=O)=C1
Formula:	C₂₃H₂₁FN₂O₅
M.Wt:	424.421649694443
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

COA

Cat. No.	Product name	Field of application
DC43987	MCHR1 antagonist 2	MCHR1 antagonist 2 is an antagonist of melanin concentrating hormone receptor 1, with an IC50 of 65 nM; MCHR1 antagonist 2 also inhibits hERG, with an IC50 of 4.0 nM in IMR-32 cells.
DC28204	SNAP 94847 hydrochloride	SNAP 94847 hydrochloride is a novel, high affinity selective melanin-concentrating hormonereceptor1 (MCHR1) antagonist with (Ki= 2.2 nM, Kd=530 pM), it displays >80-fold and >500-fold selectivity over MCHα1A and MCHD2 receptors respectively. SNAP 94847 hydrochloride binds with high affinity to the mouse and rat MCHR1 with minimal cross-reactivity to other GPCR, ion channels, enzymes, and transporters.