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MCHR1 antagonist 2

  Cat. No.:  DC43987   Featured
Chemical Structure
863115-70-2
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More than 5000 active chemicals with high quality for research!
Field of application
MCHR1 antagonist 2 is an antagonist of melanin concentrating hormone receptor 1, with an IC50 of 65 nM; MCHR1 antagonist 2 also inhibits hERG, with an IC50 of 4.0 nM in IMR-32 cells.
Cas No.: 863115-70-2
Chemical Name: MCHr1 antagonist 2
Synonyms: MCHr1 antagonist 2;N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-6-fluoro-4-oxochromene-2-carboxamide;n-(1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl)-6-fluoro-4-oxochromene-2-carboxamide;BCP33948;BDBM50197113;N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-6-fluoro-4-oxo-4H-chromene-2-carboxamide;N-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-yl)-6-fluoro-4-oxo-4H-chromene-2-carboxamide;MCHR1 antagonist 2;N-[1-(1,3-Benzodioxol-5-ylmethyl)-4-piperidinyl]-6-fluoro-4-oxo-4H-1-benzopyran-2-carboxamide (ACI)
SMILES: O=C1C2C(=CC=C(C=2)F)OC(C(NC2CCN(CC3C=C4C(OCO4)=CC=3)CC2)=O)=C1
Formula: C23H21FN2O5
M.Wt: 424.421649694443
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC43987 MCHR1 antagonist 2 MCHR1 antagonist 2 is an antagonist of melanin concentrating hormone receptor 1, with an IC50 of 65 nM; MCHR1 antagonist 2 also inhibits hERG, with an IC50 of 4.0 nM in IMR-32 cells.
DC28204 SNAP 94847 hydrochloride SNAP 94847 hydrochloride is a novel, high affinity selective melanin-concentrating hormonereceptor1 (MCHR1) antagonist with (Ki= 2.2 nM, Kd=530 pM), it displays >80-fold and >500-fold selectivity over MCHα1A and MCHD2 receptors respectively. SNAP 94847 hydrochloride binds with high affinity to the mouse and rat MCHR1 with minimal cross-reactivity to other GPCR, ion channels, enzymes, and transporters.
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