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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DCC5148 Tiemonium Iodide Muscarinic receptor antagonist, anticholinergic,and parasympatholytic
DCC5149 Tigilanol Tiglate Natural anticancer agent fortreatment of mast cell tumor (MCT)
DCC5150 Tillman Reagent Widely used oxidation-reduction indicator
DCC5151 Tilmicosin Phosphate Macrolide antibiotic for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia (Pasteurella) haemolytica
DCC5152 Tilorone Dihydrochloride Antiviral, antineoplastic, and anti-inflammatory agent; Orally active interferon inducer, inhibiting Ebola virus (EBOV)
DCC5153 Tinostamustine Hydrochloride Novel pan-histone-deacetylase inhibitor with alkylating activity
DCC5154 Tinyatoxin Neurotoxin, acting via vanilloid receptors of sensory nerves
DCC5155 Tioxolone Novel hepcidin antagonist
DCC5156 tipp-204 hPPAR
DCC5157 tipp-401 Dual PPA
DCC5158 tipp-703 hPPAR-pan agonist
DCC5159 Tiracizine Hydrochloride Anti-arrhythmia agent
DCC5160 Tl13-117 Novel AC220-based FLT3 degrader
DCC5161 Tl13-149 Novel AC220-based FLT3 degrader
DCC5162 Tli3-12 The first small molecule degrader, inducing anaplastic lymphoma kinase (ALK) degradation, including in non-small-cell lung cancer (NSCLC), anaplastic large-cell lymphoma (ALCL), and neuroblastoma (NB) cell lines
DCC5163 Tli3-i12 The first small molecule degrader, inducing anaplastic lymphoma kinase (ALK) degradation, including in non-small-cell lung cancer (NSCLC), anaplastic large-cell lymphoma (ALCL), and neuroblastoma (NB) cell lines
DCC5164 Tlk19781 Novel Insulin Receptor Modulator
DCC5165 tlr4-in-c35 Novel Toll-Like Receptor 4 (TLR4) Inhibitor
DCC5166 Tlr7/8-in-cmpd2 Novel potent and selective dual TLR7/8 inhibitor
DCC5167 Tlr8-in-5 Novel toll-like receptor 8 (TLR8) inhibitor, potently and selectively reducing TLR8-mediated signaling
DCC5168 Tls-in-5 The first small molecule inhibitor of translesion synthesis (TLS) that target Rev1-CT
DCC5169 Tm2-119 Potent histone methyltransferase inhibitor with rapid antimalarial activity against all blood stage forms in Plasmodium falciparum
DCC5170 Tm-233 Novel inhibitor of both JAK/STAT and proteasome activities, inducing cell death in myeloma cells
DCC5171 Tm5001 Novel inhibitor of plasminogen activator inhibitor-1 (PAI-1)
DCC5172 Tma-230 Penem beta-lactam antibiotic
DCC5173 Tmc-310911 Novel protease inhibitor (PI) against a variety of HIV-1 strains, including multi-PI-resistant strains, and may be less likely to generate resistance, also showing antiviral avtivity as a potential treatment for COVID-19 caused by SARS-CoV-2
DCC5174 Tm-p4-thal Dual Inhibitor of SIRT2 Deacetylase and Defatty-Acylase Activities
DCC5175 Tmp-b3a Novel degrader of E. coli DHFR (eDHFR), as well as eDHFR-EGFP fusion proteins, demonstrating that degradation does not require covalent attachment of the tag to the target protein
DCC5176 Tmp-nvoc-halo Novel caged protein labeling agent
DCC5177 Tmppaa Allosteric agonist and positive allosteric modulator (PAM) of 5-HT3 receptor

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