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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DCC5178 Tmq0153 Novel activator of necrostatin-1 sensitive necroptotic cell death, triggering apoptosis, autophagy and necroptosis crosstalk in chronic myeloid leukemia
DCC5179 Tnfalpha-in-4e Novel potent inhibitor of TNF-α
DCC5180 Tnfalpha-in-5783168 Novel inhibitor of tumor necrosis factor-α (TNF-α)
DCC5181 Tnk-6123 Emivirine analog with improved activity against drug-resistant HIV mutants
DCC5182 Tnk-651 Novel non-nucleoside reverse transcriptase inhibitor of HIV-1
DCC5183 Tnks/usp25-in-c44 Novel selective inhibitor of TNKS-USP25 interaction, effectively reducing prostate cancer cell proliferation and tumor growth
DCC5184 Tnks2-in-5 Novel highly potent and selective TNKS2 inhibitor with antiproliferative effects in a colorectal cancer cell line (DLD-1) where the Wnt pathway is constitutively activated
DCC5185 Tnks-in-1 Highly potent and selective tankyrase inhibitor
DCC5186 Tnks-in-21 Novel potent and selective tankyrase (TNKS) inhibitor
DCC5187 Tnp-2092 Unique multitargeting drug conjugate with extremely low propensity for development of resistance, targeting RNA polymerase, DNA gyrase, and DNA topoisomerase IV
DCC5188 Tol8-agonist-31a Novel Human Toll-like Receptor 8-Selective Agonist
DCC5189 Toldimfos Sodium Stimulator of metabolism, preventing diseases associated with parturition and peri-partum period, developmental and nutritional disorders in young animals, and bone growth disorders and tetany or paresis caused by calcium, magnesium, and phosphorus metabo
DCC5190 Tonantzitlolone Natural agonist of TPRC1/4/5 channels, also acting as a dual PKCα and PKCθ activator, inducing an insulin resistant phenotype by inhibiting IRS1 and the PI3K/Akt pathway, activating the heat shock factor 1 (HSF1) transcription factor driving glucose depen
DCC5191 Top1/tdp1-in-c12 Novel dual TOP1 and TDP1 inhibitor, inducing both cellular TOP1cc, TDP1cc formation and DNA damage, resulting in cancer cell apoptosis at a sub-micromolar concentration
DCC5192 Top1210 Novel narrow spectrum kinase inhibitor, potently inhibiting P38a, Src, and Syk kinase activities
DCC5193 Top-dnj Novel Selective Inhibitor of Endoplasmic Reticulum α-Glucosidase II, Exhibiting Antiflaviviral Activity
DCC5194 Topki-nbd Novel highly specific fluorescent TOPK inhibitor
DCC5195 To-pro3 Iodide Nucleic acid stain, acting on viable, early apoptotic and necrotic cells differentially, showing specific staining of nuclei without any staining of the cytoplasm
DCC5196 Tortuosamine Natural psychoactive agent
DCC5197 Tos-gly-pro-arg-anba-ipa Chromogenic peptide substrate for the rapid and specific photometric assay of recombinant hirudin (r-hirudin)
DCC5198 Tosylaniline Selective CA IX inhibitor
DCC5199 Toxt-in-8 Novel ToxT inhibitor, reducing Vibrio cholerae virulence in vivo and effectively inhibiting intestinal colonization in the infant mouse
DCC5200 Tp-008 Novel probe for activin receptor-like kinase (ALK4 and ALK5)
DCC5201 Tp-040 Novel inhibitor of O-GlcNAcase (OGA)
DCC5202 Tp-238 Hydrochloride Novel probe for CECR2/BPTF bromodomains
DCC5203 Tpe-gal First-in-class fluorescent drug delivery vesicle that can efficiently load both water-soluble and -insoluble anticancer drugs
DCC5204 Tph1-in-23a Novel Peripheral Selective Tryptophan Hydroxylase 1 (TPH1) Inhibitor (IC 50 : 42nM) for Obesity and Fatty Liver Disease
DCC5205 Tpi1609-10 Inhibitor of tyrosine recombinases and Holliday junction-resolving enzymes; Antibacterial
DCC5206 Tpi-1917-49 Promising amyloid reducing agent by lowering the levels of Aβ.
DCC5207 Tpi-2659-17 Novel Specific Inhibitor of Type I Collagen Production in Fibrosis

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