Novel Anabolic Selective Androgen Receptor Modulator (SARM)

Novel inhibitor of protein farnesyltransferase (FT), inhibiting the growth of P. falciparum in red blood cells and suppressing parasitemia

Farnesyltransferase inhibitor, inhibiting both H- and K-Ras oncogenic signaling

Novel fat mass- and obesity-associated protein (FTO) inhibitor, preventing neurosphere formation in patient-derived glioblastoma stem cells (GSCs) without inhibiting the growth of healthy neural stem cell-derived neurospheres

Novel specific high-affinity fluorescent probe for FtsZ antibacterial inhibitor

FTY720 analog as novel potent stimulator of the activity of the protein phosphatase 2A (PP2A)

FTY720 analog as novel stimulator of the activity of the protein phosphatase 2A (PP2A), targeting mitochondria

Direct inhibitor of the p53 transactivation domain from binding to replication protein A

Natural antimicrobial agent, showing neuroprotective, expectorant, and antioxidant activities

Chemosensitizing agent, selectively reversing BCRP-mediated multidrug resistance to mitoxantrone, doxorubicin, and topotecan

Highly potent dopamine D2 modulator

Anti-bacterial metabolite of Nitrofuran

Novel potent Hepatitis C virus (HCV) NS3/4A protease inhibitor

Insecticide, acting as an EC 3.1.1.7 (acetylcholinesterase) inhibitor

Natural neuroprotective agent on glutamate-mediated HT22 cell death, controlling the amount of ubiquinone, up-regulating p21 expression in a p53-dependent manner, decreasing Akt phosphorylation and resulting in increased Fas ligand production and caspase-

Novel slow-releasing hydrogen sulfide (H2S) donor, inhibiting NF-κB activity and inducing cell apoptosis

Novel highly potent Factor XIa inhibitor with selectivity against most of the relevant serine proteases

Novel potent and selective inhibitor of FXIa, producing a robust and dose-dependent inhibition of both arterial thrombosis and MES

Novel, Potent, and Nonsteroidal Farnesoid X Receptor (FXR) Selective Antagonist

Novel antiviral agent against Rift Valley fever virus (RVFV) by blocking virus budding from the trans Golgi.

Novel potent and highly specific MEK inhibitor (MEKi)

Novel fluorescent specific ligand of human telomeric G-quadruplex DNA, binding to both G-tetrad and the lateral loop near the 5-end, reducing the telomere length and downregulating hTERC and hTERT mRNA expression in HeLa cells