Novel fluorescent near-infrared (NIR) linker for building brighter labeled biomolecules, exhibiting no evidence of H-aggregation even at high labeling density when appended to monoclonal antibodies or virus-like particles

Inhibitor of IspD and IspE enzymes isolated from bacteria

Novel BRD PROTAC, being capable of degrading BRDs in a folate receptor-dependent manner in cancer cells

Novel ALK PROTAC, being capable of degrading ALK in a folate receptor-dependent manner in cancer cells

Local anaesthetic agent, blocking voltage-gated Na(+) currents in neurons

Impurity of Lenalidomide

Natural antibiotic, acting as an inhibitor of DOXP reductoisomerase

Novel dipeptidyl peptidase IV (DPP4) inhibitor

Novel Dipeptidyl Peptidase-4 (DPP-4) Inhibitor

Novel Photochromic Ion Channel Blocker

Novel NO-donating antimicrobial peptide, exhibiting Staphylococcus aureus and Escherichia coli biofilm dispersion and eradication, and potent antibacterial activities in vitro

Novel agonist of the formyl peptide receptor (FPR), protecting against myocardial ischaemia-reperfusion injury in mice

Selective ET(A) receptor antagonist

Natural specific inhibitor of mammalian NSDHL and yeast Erg26p, inhibiting an artificial Hepatitis C viral replicon, and showung broad antifungal activity

Nonprostanoid PGI2 agonist

Potent and nonadrenotoxic ACAT inhibitor

Novel Nonpeptide Bradykinin B2-Receptor Partial Agonist

Potent, selective, and orally active antagonist for central adenosine A1 receptors

Novel Potent and Selective Covalent Inhibitor of KRAS G12C

Potent ligand for a protein site governed largely by van der Waals interactions, producing excitatory activity in tadpoles and mice; also antagonizing propofol-induced hypnosis

Novel N-Methyl-d-aspartate receptor (NMDAR) positive allosteric modulator (PAM) with potential antidepressant effects

Novel highly potent and selective inhibitor (type 1.5 binding mode) of MAPK14 [IC50 = 0.2 nM (ELISA, cell free); KD = 1.5 nM (DiscoverX)]