Novel selective CHK1 inhibitor

Novel potent aryl hydrocarbon receptor (AHR) antagonist with the capacity to inhibit both DRE-dependent and -independent activity

Novel Inhibitor of EGF-EGFR Interactions

Novel inhibitor of Plasmodium falciparum, killing both blood- and sexual-stage P. falciparum parasites

Dose dependent up-regulator of the level of E-cadherin in SW620 cells

Natural highly potent HIV latency-reversing agent

Novel inhibitor of Gram-negative lipoprotein trafficking

Novel potent GNMT inducer, inhibiting Huh7 cell growth in vitro and xenograft in vivo

Dual Glycolate Oxidase/Lactate Dehydrogenase A (GO/LDHA) Inhibitor for Primary Hyperoxaluria

Agonist of the GnRH receptor, inducing the secretion of the gonadotropins follicle-stimulating hormone and luteinizing hormone from the pituitary gland and to increase sex hormone production by the gonads

Natural inhibitor of Musashi family of RNA-binding proteins

Antipsychotic and cognitive enhancer; Dopamine D1 and D2 receptor modulator

Natural potent inducer of apoptosis in MCF-7 cell lines

Curcumin analog, exhibiting potent growth suppressive activity in human colorectal carcinoma cells

Novel selective non-steroidal agonist of G-protein bile acid receptor 1 (GPBAR1, also known as TGR5 or M-BAR)

Potent PARP inhibitor

Novel potent GPR120 agonist, exhibiting significant glucose-lowering effect and high selectivity over GPR40

Novel potent GPR52 agonist, dose-dependently suppressing methamphetamine-induced hyperlocomotion in mice

The first orally active GPR52 agonist

Highly potent and specific GPR52 antagonist

Novel, potent, efficacious, and brain-penetrant GPR88 agonist (cAMP EC 50 = 14 nM)

Novel potent GPR88 agonist (EC 50 = 59 nM)