Fragment 177-191 of human growth hormone, regulating fat metabolism but without the adverse effects on blood sugar or growth, stimulating lipolysis (the breakdown or destruction of fat) and inhibiting lipogenesis (the transformation of nonfat food materia

Novel sulfur-triazole exchange (SuTEx) covalent probe with ~5-fold enhanced chemoselectivity for tyrosines over other nucleophilic amino acids

Positive allosteric modulator at the barbiturate/picrotoxin site of the GABAA receptor

Non-nucleoside reverse transcriptase inhibitor

Potent non-nucleoside inhibitor of drug-resistant human immunodeficiency virus (HIV)

Potent inhibitor of multidrug-resistant human immunodeficiency virus-1 (HIV-1)

Hexapeptide sequences of hIAPP, being sufficient for the formation of beta-sheet-containing amyloid fibrils and coiling around each other in a typical amyloid fibril morphology

Pentapeptide sequences of hIAPP, being sufficient for the formation of beta-sheet-containing amyloid fibrils and self-assemble laterally into unusually broad ribbons

CNS active anticonvulsant and ultra-short acting hypnotic

Novel HIF-1alpha inhibitor

Novel HIF-1alpha-p300 Protein Protein Interaction inhibitor

Novel hypoxia inducible factor hydroxylase modulator

Novel hypoxia inducible factor hydroxylase modulator

Novel HIF Pathway Inhibitor

Natural muscarinic receptor antagonist

Novel Potent Inhibitor of HIPK1/HIPK2 Kinase

Natural alkaloid, demonstrating significant cytotoxicity against a panel of human and murine tumor cell lines

Allosteric inhibitor of ATP phosphoribosyltransferase (ATPPRT), binding to the ATPPRT:ATP complex via a two-step binding mechanism, inhibiting ATPPRT competitively and likely uncompetitively, respectively, against PRPP and ATP

Novel enhancer of catalytic efficiency of neurolysin

Novel enhancer of catalytic efficiency of neurolysin

Novel photoaffinity-labeled probe for full-length human immunodeficiency virus-1 integrase (HIV-1 IN)

Novel highly potent HIV-1 inhibitor with broad-spectrum activity (EC50 = 2.0-57 nM) against resistant strains, exhibiting good solubility and safety profiles and a good PK profile with an oral bioavailability of 59% in rats