Cat. No. | Product name | CAS No. |
DC20008 |
PI3Kδ-IN-1
Featured
PI3Kδ-IN-1 is a potent, selective, and efficacious PI3Kδ inhibitor with an IC50 of 1.7 nM. |
1911564-39-0 |
DC20502 |
PI3Kδ-IN-7n
PI3Kδ-IN-7n is a highly potent and selective PI3Kδ inhibitor with IC50 of 0.9 nM, displays high selectivity (>1,500-fold) over PI3Kα, PI3Kβ, PI3Kγ (IC50>1.5 uM). |
2088525-31-7 |
DC22508 |
PI4KIIIβ-IN-9
PI4KIIIβ-IN-9 is a potent and selective inhibitor of PI4KIIIβ (IC50=7 nM). |
1429624-84-9 |
DC12466 |
PIAA
PIAA is a TBK1/IKKε inhibitor with IC50 of 0.40/1.07 uM, selectively accelerates proliferation of β-cells. |
851814-28-3 |
DC23700 |
Piclamilast
Piclamilast (RP-73401) is a potent and highly selective PDE4 inhibitor with IC50 of 1.2 nM. |
144035-83-6 |
DC21511 |
Pico145
Pico145 is a highly potent, subtype-selective TRPC1/4/5 channels inhibitor with potency ranged from 9 to 1300 pM, depending on the TRPC1/4/5 subtype and activation mechanism. |
1628287-16-0 |
DC7949 |
Picoxystrobin
Picoxystrobin is an methoxyacrylate strobilurin fungicide designed for the control of wide range of cereal diseases. |
117428-22-5 |
DC9505 |
Pifithrin-α (hydrobromide)
Featured
Pifithrin-α is an inhibitor of p53, inhibiting p53-dependent transactivation of p53-responsive genes. |
63208-82-2 |
DC8144 |
Pifithrin-β (hydrobromide)
Featured
Pifithrin-β HBr (Cyclic Pifithrin-α HBr) is a potent p53 inhibitor with IC50 of 23 uM in an antiproliferative assay in the human ovarian carcinoma cell line, IGROV-1. |
511296-88-1 |
DC7233 |
Pifithrin-u
Featured
Pifithrin-μ is a specific p53 inhibitor by reducing its affinity to Bcl-xL and Bcl-2, and also inhibits HSP70 function and autophagy. |
64984-31-2 |
DC8254 |
PIK-93
Featured
PIK-93 is the first potent, synthetic PI4K (PI4KIIIβ) inhibitor with IC50 of 19 nM; shown to inhibit PI3Kα with IC50 of 39 nM. |
593960-11-3 |
DC21938 |
Pim inhibitor 28
Pim inhibitor 28 is a potent, selective inhibitor of Pim1/2 with IC50 of 0.05 nM for both, demonstrates on-target Pim activity in an in vivo pharmacodynamic assay with significant inhibition of BAD phosphorylation in KMS-12-BM multiple myeloma tumors.. |
|
DC9593 |
Pim1/AKK1-IN-1
PIM/AKK1-IN-1 is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively; also inhibits MPSK1 and TNIK. |
1093222-27-5 |
DC23557 |
Pim-IN-22m
Pim-IN-22m is a potent, selective Pim1/Pim2 inhibitor with IC50 of 24/95 pM respectively. |
1405126-60-4 |
DC20505 |
Pimozide
Featured
Pimozide is an antipsychotic agent that acts as an antagonist of the D2, D3, and D4 receptors and the 5-HT7 receptor, also is an inhbitor of STAT5. |
2062-78-4 |
DC12584 |
API-1
Pin1 inhibitor API-1 (API-1) is a potent, specific inhibitor of peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) and inhibits Pin1 cis-trans isomerizing activity with IC50 of 72.3 nM, displays remarkable selectivity over other peptidyl-prolyl |
680622-70-2 |
DC21939 |
PIN1 inhibitor VS10
PIN1 inhibitor VS10 is a novel potent small molecule inhibitor of PIN1 (peptidyl-prolyl cis-trans isomerase, NIMA-interacting 1), inhibits human PIN1 isomerization with IC50 of 13.4 uM, displays >2-fold more potency than ATRA. |
920849-78-1 |
DC12096 |
Pinacidil monohydrate (Pinacidil hydrate)
Featured
Pinacidil monohydrate, an antihypertensive drug, is a potassium channel activator. |
85371-64-8 |
DCAPI1413 |
pioglitazone hydrochloride
Featured
Pioglitazone Hydrochloride is the hydrochloride salt preparation of Pioglitazone, a specific ligand of PPAR-γ (peroxisome proliferator-activated receptor-γ). Pioglitazone is a thiazolidinedione compound described to produce antiinflammatory and antiarteri |
112529-15-4 |
DC24186 |
Piperazine Erastin
Featured
Piperazine Erastin is an analog of Erastin, which can induces ferroptosis in cancer cells, an iron-dependent form of nonapoptotic cell death.. |
1538593-71-3 |
DC9629 |
Azaphen (dihydrochloride monohydrate)
Pipofezine(Azafen or Azaphen) is a potent inhibitor of the reuptake of serotonin. |
63302-99-8 |
DC23685 |
Piragliatin
Piragliatin (RO 4389620. |
625114-41-2 |