Cat. No. | Product name | CAS No. |
DC8145 |
Phen-DC 3
Phen-DC 3|Phen-DC-3,Phen-DC3|DC Chemicals |
942936-75-6 |
DC1110 |
Phenprocoumon (Marcumar)
Phenprocoumon is closely related to warfarin and is an anticoagulant drug used to thin the blood, or stop it from clotting. |
435-97-2 |
DC12183 |
Phenylbiguanide (N-Phenylbiguanide; PBG; 1-Phenylbiguanide)
Phenylbiguanide is a 5-HT3 receptor selective agonist with an EC50 of 3.0±0.1 μM. |
102-02-3 |
DC9449 |
Phenylpiracetam
Phenylpiracetam(Phenotropyl; Phenotropil) is a phenylated derivative of the nootropic drug piracetam. |
77472-70-9 |
DC20127 |
PhiKan 083
PhiKan 083 is a carbazole derivative, which binds to the surface cavity and stabilizes Y220C (a p53 mutant), with a Kd of 167 μM, and a relative binding affinity (Kd) of 150 μM in Ln229 cells. |
880813-36-5 |
DC10763 |
Philanthotoxin 74 (hydrochloride)
Featured
Philanthotoxin 74 dihydrochloride (PhTx 74) is an AMPAR antagonist; inhibits GluR3 and GluR1 with IC50s of 263 and 296 nM, respectively. |
1227301-51-0 |
DC8671 |
Phosalone
Phosalone is a member of the organophosphate family of insecticides. It is used as both an insecticide and acaricide. |
2310-17-0 |
DC20255 |
Phosphate and amino acid prodrug of Atazanavir
Phosphate and amino acid prodrug of Atazanavir gives four-fold improved AUC and eight-fold higher Ctrough values of Atazanavir. |
|
DC21508 |
Phosphonoacetohydroxamate
Phosphonoacetohydroxamate (PhAH) is a potent Enolase inhibitor with IC50 of 53.2 nM and 62.3 nM for recombinant hENO1 and hENO2 respectively. |
89893-77-6 |
DC23766 |
Phox-I1
Phox-I1 is a small molecule inhibitor that targets the interactive site of p67(phox) with Rac GTPase with Kd of 100 nM. |
1388151-90-3 |
DC11243 |
PHY34
PHY34 is a potent autophagy inhibitor with cytotoxic effects by inhibiting autophagy at a late stage (MDA-MB-435 IC50=23 nM, MDA-MB-231 IC50=5.2 nM). |
2130033-55-3 |
DC7232 |
PI-103
Featured
PI103 is a potent inhibitor with low IC50 values against recombinant PI3K isoforms p110alpha (IC50= 2 nM), p110beta (IC50= 3 nM), p110delta (IC50= 3 nM), and p110gamma (IC50= 15 nM), less potent to mTOR/DNA-PK with IC50 of 30 nM/23 nM. |
371935-74-9 |
DC21062 |
GPI-16552
PI-16552 is a potent, specific poly(ADP-ribose) glycohydrolase (PARG) inhibitor with IC50 of 1.7 uM. |
443794-40-9 |
DC21510 |
PI-273
PI-273 (PI273) is a potent, specific, substrate-competitive small molecule inhibitor of PI4KIIα with IC50 of 0.47 uM. |
925069-34-7 |
DC20090 |
PI3K/mTOR Inhibitor-1
PI3K/mTOR Inhibitor-1 is a potent, orally bioavailable dual PI3K/mTOR inhibitor with IC50s of 20/376/204/46 nM and 186 nM for PI3Kα/PI3Kβ/PI3Kγ/PI3Kδ and mTOR, respectively. Antitumor activity. |
1949802-49-6 |
DC20036 |
PI3K/mTOR Inhibitor-2
Featured
PI3K/mTOR Inhibitor-2 is a potent dual pan-PI3K/mTOR inhibitor with IC50s of 3.4/34/16/1 nM for PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ and 4.7 nM for mTOR. Antitumor activity. |
1848242-58-9 |
DC20503 |
PI3K-IN-16
PI3K-IN-16 is a potent and selective, orally bioavailable PI3Kβ and PI3Kδ inhibitor with cell IC50 of 12 nM (in PTEN null MDA-MB-468 cell) and 47 nM (in Jeko-1 B-cell), respectively. |
1895876-81-9 |
DC20504 |
PI3K-IN-8q
PI3K-IN-8q is a potent, selective dual p110α/p110δ inhibitor with Ki app of 3.3/8.36 nM respectively. |
1280204-67-2 |
DC20499 |
PI3Kα-IN-4h
PI3Kα-IN-1 is a potent, selective, ATP-competitive dual PI3Kα/mTOR inhibitor with IC50 of 0.5/104 nM respectively. |
2100855-80-7 |
DC20500 |
PI3Kα-IN-5
PI3Kα-IN-5 is a potent, selective PI3Kα inhibitor with enzyme IC50 and cell IC50 of 6 nM and 87 nM respectively, exhibits 100-fold selectivity over PI3Kβ. |
2101744-13-0 |
DC8531 |
TASP0415914
Featured
PI3Kγ is required for for T-cell and B-cell as well as mast cell migration and degranulation. As such, these kinases are attractive targets for potential anti-infmamatory drugs. TASP0415914 has shown excellent results in cell based assays. It is orally av |
1292300-75-4 |
DC7874 |
PI3k(delta) inhibitor 1
PI3kδ inhibitor 1 is a potent and selective inhibitor of isoform of PI3Kδ; useful for treating disorders mediated by lipid kinases such as inflammation, immunol disorders, and cancer. |
1332075-63-4 |