Cat. No. | Product name | CAS No. |
DC11138 |
Guanabenz acetate
R15A inhibitor. |
23256-50-0 |
DC22205 |
R191
R191 (R-191) is a potent, small molecule IRAK1/4 kinase inhibitor (IRAK4 IC50=3 nM), exhibits good selectivity against a broad panel of kinases. |
|
DC22670 |
R243
Featured
R243 is a potent, small molecule CCR8 antagonist that inhibits CCR8 signaling and chemotaxis, inhibits CCL1-induced Ca2+ flux and CCL1-driven peritoneal macrophages aggregation at 0.2 uM. |
688352-84-3 |
DC21551 |
R-360163
R-360163 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 16 uM in FP assay. |
883791-50-2 |
DC2068 |
R547
R547 is a potent and selective CDK inhibitor with Ki and IC50 of 1-3 nM and 80 nM respectively. |
741713-40-6 |
DC9462 |
R-7128(Mericitabine)
Featured
R-7128(Mericitabine) is a selective nucleoside analog inhibitor of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, with activity across all HCV genotypes. |
940908-79-2 |
DC10995 |
R916562
R916562 (R562) is a potent, dual Axl/VEGF-R2 inhibitor with celluar IC50 of 136 nM for Axl. |
1037798-41-6 |
DC21555 |
R-999636
R-999636 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 8.8 uM in FP assay. |
90833-53-7 |
DC10304 |
RA190
RA190, a bis-benzylidine piperidon, inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13. |
1617495-03-0 |
DC21544 |
rac Pterosin B
rac Pterosin B is a potent and specific SIK3 signaling inhibitor that suppresses SIK3 downstream cascades by up-regulating the phosphorylation levels in the SIK3 C-terminal regulatory domain. |
60657-37-6 |
DC20528 |
RAD51-IN-1
Featured
RAD51-IN-17 is a quinazolinone derivative that inhibts homologous recombinase RAD51, effectively inhibits both RAD51 foci formation in response to DNA damage, and proliferation of TNBC cell lines. |
2101739-18-6 |
DC9513 |
Radafaxine (hydrochloride)
Featured
Radafaxine Hcl(BW-306U; GW-353162A) is a potent metabolite of bupropion; selective for inhibiting the reuptake of norepinephrine over dopamine; DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulat |
106083-71-0 |
DC21069 |
Radalbuvir
Radalbuvir (GS-9669) is a highly optimized thumb site II nonnucleoside inhibitor of HCV NS5B polymerase with binding affinity of 1.35 nM for genotype 1b. |
1314795-11-3 |
DC9351 |
Radezolid
Featured
Radezolid (RX-1741) is a novel oxazolidinone antibiotic agent. |
869884-78-6 |
DC8930 |
Rafoxanide
Rafoxanide is a salicylanilide used as an antiparasitic agent. |
22662-39-1 |
DC9479 |
Raltegravir (potassium salt)
Raltegravir potassium salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection. |
871038-72-1 |
DC6918 |
Ramatroban (BAY u3405)
Ramatroban (BAY u3405) is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis. |
116649-85-5 |
DC7828 |
Ramelteon
Ramelteon is a novel melatonin receptor agonist for human MT1 and MT2 receptors and chick forebrain melatonin receptors with Ki of 14 pM, 112 pM and 23.1 pM, respectively. |
196597-26-9 |
DC11816 |
RapaLink-1
Featured
RapaLink-1 is a third-generation mTOR inhibitor that overcomes resistance to existing first- and second-generation inhibitors; blocks mTOR signaling of the F2108L mTOR and M2327I mTOR drug resistant mutants; RapaLink-1 is more potent mTOR inhibitor than rapamycin. |
1887095-82-0 |
DC12624 |
RAS activator compound 1
Featured
RAS activator compound 1 is a small molecule RAS activator compound that increases the rate of SOS-catalyzed nucleotide exchange in vitro with EC50 of 14 uM; targets SOS1 induced biphasic modulation of RAS-GTP and ERK phosphorylation levels, through negative feedback on SOS1 that regulates the interaction between SOS1 and GRB2. |
1579978-17-8 |
DC11216 |
RAS inhibitor Abd-7
RAS inhibitor Abd-7 is a potent RAS-binding compound (Kd=51 nM) that interacts with RAS in cells, prevents RAS-effector interactions and inhibits endogenous RAS-dependent signalling. |
2351843-48-4 |
DC10949 |
RasGRP3 ligand 96
Featured
RasGRP3 ligand 96 is a potent, selective ligand of Ras guanine-releasing protein 3 (RasGRP3) with Ki of 1.75 nM, showed 73-fold and 45-fold selectivity relative to PKCα and PKCε for in vitro binding activity resepctively. |
2229068-13-5 |