Cat. No. | Product name | CAS No. |
DC26099 |
SR-16435
SR-16435 is a mixed NOP/μ-opioid partial agonist with equally high affinity (Ki=29 nM) for both NOP and μ-opioid receptors. |
857262-16-9 |
DC22422 |
SR-16835
SR-16835 is a potent full agonist of ORL1 receptor (NOP receptor) with binding Ki of 11.4 nM, with low-affinity mu-opioid partial agonist activity (Ki=79.9 nM). |
1207195-45-6 |
DC11604 |
SR-20295
SR-20295 (SR20295) is a novel potent ULK1 inhibitor with IC50 of 45 nM.. |
2166091-48-9 |
DC11046 |
SR2211
SR2211 (SR-2211) is a potent, selective RORγ inverse agonist (Ki=105 nM, IC50=320 nM) that potently inhibits production of IL-17 in cells. |
1359164-11-6 |
DC21687 |
SR31527
Featured
SR31527 is a novel allosteric Kinesin-like protein KIFC1 inhibitor that inhibits microtubule-stimulated KIFC1 ATPase activity with IC50 of 6.6 uM, binds directly to KIFC1 with Kd of 25.4 nM. |
311814-78-5 |
DC23175 |
SR-3306
SR-3306 is a highly selective, brain penetrant, potent inhibitor of JNK with IC50 of 67, 283 and 159 nM for JNK1, JNK2 and JNK3, >100-fold selectivity over p38. |
1128096-91-2 |
DC9615 |
SR3335
Featured
SR3335 (ML-176) is a selective RORα synthetic ligand, directly binds to RORα, but not other RORs, and functions as a selective partial inverse agonist of RORα in cell-based assays. |
293753-05-6 |
DC22234 |
SR-57227 hydrochloride
SR-57227 is a high affinity, selective 5-HT3 receptor agonist, demonstrates anticonvulsant effects in vivo.. |
77145-61-0 |
DC22233 |
SR-57227
SR-57227 is a high affinity, selective 5-HT3 receptor agonist, demonstrates anticonvulsant effects in vivo.. |
77145-51-8 |
DC22235 |
SR7826
SR7826 is a potent and selective LIM kinase (LIMK) inhibitor with IC50 of 43 nM, displays >100-fold selectivity over ROCK1 and ROCK2, as well as JNK kinases (>400-fold). |
1219728-20-7 |
DC21694 |
SRI 37892
SRI 37892 (SRI37892) is a novel potent, small molecule Frizzled 7 (Fzd 7) inhibitor with IC50 of 0.66 uM in Wnt/β-catenin assay. |
1030769-75-5 |
DC11242 |
SRI-31142
SRI-31142 (SRI31142) is a novel potent, putative allosteric dopamine transporter (DAT) inhibitor with Ki of 1.9 nM.. |
1940118-04-6 |
DC11939 |
SRPIN-803
SRPIN-803 (SRPIN 803, SRPIN803) is a novel small molecule dual inhibitor of SRPK1 and CK2 with IC50 of 2.4 uM and 0.2 uM, respectively, does not inhibit SRPK2. |
380572-02-1 |
DC20098 |
SRPKIN-1
SRPKIN-1 is a covalent and irreversible SRPK1/2 inhibitor with IC50s of 35.6 and 98 nM, respectively. Anti-angiogenesis effect. |
2089226-94-6 |
DC23355 |
SRT 2183
SRT 2183 is a potent, selective SIRT1 activator with EC1.5 of 0.36 uM, displays good selectivity for activation of SIRT1 versus SIRT2 and SIRT3 (EC1.5>300 uM) and is more potent than Resveratrol. |
1001908-89-9 |
DC23364 |
SRT 1460
SRT1460 is a potent, selective SIRT1 activator with EC1.5 of 2.9 uM, displays good selectivity for activation of SIRT1 versus SIRT2 and SIRT3 (EC1.5>300 uM) and is more potent than Resveratrol. |
925432-73-1 |
DC11156 |
SRTCX1002
SRTCX1002 (SRTCX-1002) is a small molecule activator of SIRT1 (STAC) with EC1.5 of 0.4 uM, enhances deacetylation of cellular p65 protein with IC50 of 0.84 uM in cellular p65 acetylation assay. |
1203479-63-3 |
DC11157 |
SRTCX1003
SRTCX1003 (SRTCX-1003) is a small molecule activator of SIRT1 (STAC) with EC1.5 of 0.61 uM, enhances deacetylation of cellular p65 protein with IC50 of 1.42 uM in cellular p65 acetylation assay. |
1203480-93-6 |
DC10651 |
SSD114 hydrochloride
Featured
SSD114 is a novel GABAB positive allosteric modulator. |
2319790-02-6 |
DC22062 |
SSR125543
SSR125543 (Crinecerfont, SSR-125543) is a potent, nonpeptide, orally active corticotropin-releasing factor (CRF) receptor CRF1 antagonist, shows anxiolytic- and antidepressant-like activities in vivo. . |
752253-39-7 |
DC21697 |
SSR 411298
SSR411298 is a highly selective, brain penetrant and orally-active inhibitor of FAAH with IC50 of 62.5 nM (mouse brain FAAH). |
666860-59-9 |
DC11791 |
SSTC3
SSTC3 is a novel small-molecule CK1α activator with EC50 of 30 nM (WNT-driven reporter gene assay), Kd of 32 nM. |
1242422-09-8 |