Cat. No. | Product name | CAS No. |
DC10188 |
Lodoxamide
Featured
Lodoxamide is an antiallergic compound acting as a mast-cell stabilizer for the treatment of asthma and allergic conjunctivitis. |
53882-12-5 |
DC10694 |
Loflucarban
Featured
Loflucarban is an antiinfective drug |
790-69-2 |
DC12324 |
Loganetin
Loganetin is a non-toxic natural product that may be applied in the antibacterial drug development for treating multidrug-resistant Gram negative infections. |
29748-10-5 |
DC12142 |
LOM612
LOM612 is a potent activator of FOXO nuclear translocation, with an EC50 value of 1.5 μM in cells. |
2173232-79-4 |
DCAPI1400 |
Lomefloxacin HCl (Maxaquin)
Lomefloxacin HCl (Maxaquin) |
98079-52-8 |
DC7188 |
Lomeguatrib(PaTrin-2)
Featured
Lomeguatrib (PaTrin-2) is a modified guanine base, which can repress the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) with an IC50 value of 6 nM. |
192441-08-0 |
DC9177 |
Lomerizine hydrochloride
Lomerizine dihydrochloride is a relatively new L- and T-type calcium channel blocker used in the treatment of migraine. |
101477-54-7 |
DC7778 |
Lometrexol(LY 264618)
Featured
Lometrexol is a tight-binding antifolate inhibitor of the purine de novo enzyme glycinamide ribonucleotide formyltransferase (GARFT), was the first GARFT inhibitor to be investigated clinically. |
106400-81-1 |
DC7900 |
AEGR-733(Lomitapide)
Featured
Lomitapide (AEGR-733) is a novel proprietary MTP-inhibitor. |
182431-12-5 |
DCAPI1049 |
Lomustine (CeeNU)
Lomustine (CeeNU) |
13010-47-4 |
DC7455 |
Lonafarnib
Featured
Lonafarnib(Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively. |
193275-84-2 |
DCAPI1199 |
Lonidamine
Featured
Lonidamine (AF-1890) is a hexokinase and mitochondrial pyruvate carrier inhibitor (Ki: 2.5 μM). Lonidamine also inhibits aerobic glycolysis in cancer cells. Lonidamine can be used in the research of mitochondrial metabolism and inflammation, such as pulmonary fibrosis. |
50264-69-2 |
DC9168 |
Loperamide HCl
Loperamide HCl is an opioid-receptor agonist used as long-acting synthetic antidiarrheals. |
34552-83-5 |
DC8907 |
Lopinavir
Featured
Lopinavir is a potent HIV protease inhibitor with Ki of 1.3 pM,showed potent activity against COVID-19(SARS-COV-2). |
192725-17-0 |
DC21250 |
Lopixibat chloride
Lopixibat chloride (LUM-001, HP-625) is a potent, selectiove, oral inhibitor of sodium bile acid cotransporter and Ileal bile acid transporter (IBAT).. |
228113-66-4 |
DC1011 |
Lorcaserin
Featured
Lorcaserin (APD-356)is a weight-loss drug developed by Arena Pharmaceuticals. It has serotonergic properties and acts as an anorectic. |
616202-92-7 |
DC8644 |
Lorcaserin Hydrochloride
Featured
Lorcaserin (APD-356)is a weight-loss drug developed by Arena Pharmaceuticals. It has serotonergic properties and acts as an anorectic. |
846589-98-8 |
DC8645 |
Lorcaserin hydrochloride heMihydrate
Lorcaserin (APD-356)is a weight-loss drug developed by Arena Pharmaceuticals. It has serotonergic properties and acts as an anorectic. |
856681-05-5 |
DC10254 |
L-Ornithine
L-ornithine has an antifatigue effect by increasing the efficiency of energy consumption and promoting the excretion of ammonia. It is one of the key reactants in the urea cycle. |
70-26-8 |
DC8356 |
Losartan Carboxylic Acid
Featured
Losartan carboxylic acid is a physiologically active metabolite of losartan, produced by cytochrome P450 isoforms in the liver. |
124750-92-1 |
DC2105 |
Lovastatin (MK-803)
Featured
Lovastatin is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM, used for lowering cholesterol (hypolipidemic agent). |
75330-75-5 |
DC8066 |
Loxiglumide
Featured
Loxiglumide is a Exogenous cholecystokinin (CCK-A) receptor antagonist, stimulates calorie intake and hunger feelings in humans. |
107097-80-3 |
DC22338 |
Larotrectinib (LOXO-101 free base)
Featured
LOXO-101 is a small molecule that was designed to block the ATP binding site of the TRK family of receptors, with 2 to 20 nM cellular potency against the TRKA, TRKB, and TRKC kinases. |
1223403-58-4 |
DC10867 |
LP-211
Featured
LP-211 is a selective and blood−brain barrier penetrant 5-HT7 receptor agonist, with a Ki of 0.58 nM, with high selectivity over 5-HT1A receptor (Ki, 188 nM) and D2 receptor (Ki, 142 nM). |
1052147-86-0 |
DC23403 |
LP99
Featured
LP99 is the first potent and selective BRD7/9 bromodomain inhibitor with Kd of 99 nM for BRD9. |
1808951-93-0 |
DC20000 |
LR-90
Featured
LR-90 is an advanced glycation end product (AGE) inhibitor, inhibits inflammatory responses in human monocytes. LR-90 is also used in the research of diabetic animal model. |
245075-84-7 |
DC20086 |
LRE1
Featured
LRE1 is a specific and allosteric inhibitor of soluble adenylyl cyclase. |
1252362-53-0 |
DC12514 |
LSD1 inhibitor 24
LSD1 inhibitor 24 is a novel potent, selective lysine-specific demethylase 1 (LSD1) inhibitor with IC50 of 1 nM, induces CD11b expression in THP-1 cells with EC50 of 8 nM. |
1853269-07-4 |
DC22396 |
LSD1 inhibitor-1
LSD1 inhibitor-1 is a bisguanidine polyamine analogue that exhibits noncompetitive and specific LSD1 inhibition, with 14.1% remaining LSD1 activity at 10 uM in vitro. |
927019-63-4 |
DC23384 |
LSD1-IN-11p
LSD1-IN-11p is a reversible LSD1 inhibitor with IC50/Kd of 79/21 nM. |
2101951-67-9 |
DC23379 |
LSD1-IN-32
LSD1-IN-32 is a potent, reversible lysine specific demethylase 1 (LSD1) inhibitor with biochemical IC50 of 83 nM, Kd of 32 nM, cell EC50 of 0.67 uM. |
2137044-49-4 |
DC8698 |
L-SelenoMethionine
L-SelenoMethionine is a major natural food-form of selenium. |
3211-76-5 |
DC21249 |
LSN 3213128
Featured
LSN 3213128 is a novel potent, selective and orally-bioavailable antifolate with potent and specific inhibitory activity for AICARFT. |
1941211-99-9 |
DC7878 |
LSN2814617
Featured
LSN2814617 is a neurotoxic positive allosteric modulator. |
1313498-08-6 |
DC23503 |
LSP1-2111
LSP1-2111 is a potent, selective, and brain penetrant group III mGluRs agonist with EC50 of 2.2 and 1.7 uM for mGluR4 and mGluR6, respectively. |
936234-43-4 |
DC26113 |
LSP4–2022
Featured
LSP4–2022 is a novel potent, selective, brain-penetrant mGluR4 agonist with EC50 of 0.11 uM in cell-based assays. |
1413405-33-0 |
DCAPI1211 |
L-Thyroxine
L-Thyroxine |
51-48-9 |
DC10072 |
LTI-291
Featured
LTI-291 is a Glucocerebrosidase (Gcase) activator for the treament of Parkinson's disease (PD). |
1919820-28-2 |
DC10155 |
LTURM34
LTURM34 is a specific DNA-PK inhibitor with an IC50 of 0.034 μM. |
1879887-96-3 |
DC24031 |
LTV-1
LTV-1 is a highly potent, cell-permeable and reversible LYP (lymphoid tyrosine phosphatase) inhibitor with IC50 of 508 nM. |
347379-29-7 |
DC10987 |
LTX-315
This product is discontinued. LTX-315 (Oncopore) is a synthetic 9-mer anticancer peptide that preferentially permeabilizes mitochondrial membranes, thereby causing partially BAX/BAK1-regulated, caspase-independent necrosis. |
1345407-05-7 |
DC10988 |
LTX-401
The product is discontinued. LTX-401 (LTX401) is an oncolytic amino acid derivative with potential immunogenic properties, selectively destroys the structure of the Golgi apparatus. |
1262851-70-6 |
DC9784 |
Lu AF21934
Featured
Lu AF21934 is a brain-penetrating positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4),reduces the harmaline-induced hyperactivity |
1445605-23-1 |
DC8287 |
Lubiprostone
Featured
Lubiprostone(SPI-0211;RU0211) is a gastrointestinal agent used for the treatment of idiopathic chronic constipation. |
136790-76-6 |
DC7170 |
Lucidin (NSC 30546)
Lucidin (NSC 30546) is a natural component of Rubia tinctorum L. lucidin is mutagenic in bacteria and mammalian cells. |
478-08-0 |
DC22596 |
LUF6000
LUF6000 is a potent, selective, positive allosteric modulator (enhancer) of human A3 adenosine receptor, enhance Emax but without affecting agonist potency. |
890087-21-5 |
DC23647 |
LUF7346
Featured
LUF7346 is a novel hERG allosteric modulator that slows IKr deactivation and positively shifting IKr inactivation. |
1821638-40-7 |
DC8611 |
Luliconazole
Featured
Luliconazole(NND 502) is an azole antifungal indicated for the topical treatment of interdigital tinea pedis. |
187164-19-8 |
DC22906 |
Lumateperone
Featured
Lumateperone (ITI-007) is a potent 5-HT2A antagonist (Ki=0.54 nM), postsynaptic D2 antagonist(Ki=32 nM), and SERT blocker (Ki= 61 nM). |
313368-91-1 |
DC20271 |
LUT014
Featured
LUT014 is a novel BRAF agonist. |
2274819-46-2 |
DC12120 |
Luteolin-7-rutinoside
Luteolin-7-rutinoside has both anti-arthritic and antifungal activities, can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection. |
20633-84-5 |
DC23133 |
LX-1031
LX-1031 is a potent, orally active tryptophan 5-hydroxylase (TPH) inhibitor with potency of 10-100 nM, reduces 5-HT synthesis peripherally. |
945976-76-1 |
DC21251 |
LX-2931
LX-2931 (LX2931) is a potent, selective and orally bioavailable S1P lyase (S1PL) inhibitor. |
948840-25-3 |
DC23136 |
LX7101
LX7101 is a potent, dual LIMK and ROCK inhibitor with IC50 of 4.3/32//69/32/ nM for LIMK2/LIMK1/ROCK1/ROCK2, respectively. |
1192189-69-7 |
DC26012 |
LXS-196
Featured
LXS196 is a potent, selective and orally active protein kinase C (PKC) inhibitor, with IC50 values of 1.9 nM, 0.4 nM and 3.1 μM for PKCα, PKCθ and GSK3β, respectively. It can be used for the treatment of uveal melanoma. |
1874276-76-2 |
DC21256 |
LY 2318912
LY 2318912 is a potent, competitive, small molecule inhibitor of anandamide uptake with IC50 of 7.27 nM, shows high affinity against anandamide transporter binding site with Kd o f7.62 nM. |
874902-18-8 |
DC8602 |
LY311727
Featured
LY 311727 is a specific group II sPLA2 (phospholipase A2 (PLA2)) inhibitor which has been reported to attenuate VEGF-mediated platelet-activating factor (PAF) synthesis in HUVEC and BAEC cells. |
164083-84-5 |
DC23633 |
LY 392098
LY 392098 is a selective, potent and centrally active positive allosteric modulator of AMPAR. |
211311-39-6 |
DC7944 |
LY2090314
Featured
LY2090314 is a potent inhibitor of glycogen synthase kinase-3 (GSK-3) with IC50s of 1.5 nM and 0.9 nM for GSK-3α and GSK-3β respectively. |
603288-22-8 |
DC12130 |
LY223982
LY223982 is a potent and specific inhibitor of leukotriene B4 receptor, with an IC50 of 13.2 nM against [3H]LTB4 binding to LTB4 receptor. |
117423-74-2 |
DC9304 |
LY2334737
Featured
LY2334737 is an orally available prodrug of gemcitabine which is a nucleoside analog used as chemotherapy. |
892128-60-8 |
DC9975 |
Ly 2365109 Hydrochloride;n-[2-[4-(1,3-benzodioxol-5-yl)-2-(1,1-dimethylethyl)phenoxy]ethyl]-n-methylglycinehydrochloride
Featured
LY2365109 is a potent and selective GlyT1 inhibitors with IC50 value of 15.8 nM. |
868265-28-5 |
DC23720 |
LY2452473
Featured
LY2452473 is an orally bioavailable, selective androgen receptor modulator (SARM). |
1029692-15-6 |
DC24072 |
LY-2584702 free base
Featured
LY2584702 is a potent, selective, ATP-competitive inhibitor of P70 S6 kinase-1 (p70S6K1) with IC50 of 4 nM. |
1082949-67-4 |
DC24073 |
LY-2584702 hydrochloride
Featured
LY2584702 is a potent, selective, ATP-competitive inhibitor of P70S6 kinase-1 (p70S6K1) with IC50 of 4 nM. |
1082948-81-9 |
DC7458 |
LY2608204
Featured
LY2608204 is a activator of glucokinase (GK) with EC50 of 42 nM. |
1234703-40-2 |
DC22140 |
LY2623091
LY2623091 (LY-2623091) is an orally administered mineralocorticoid receptor antagonist for the treatment of essential hypertension and chronic kidney disease.. |
1162264-07-4 |
DC23444 |
LY2624803
LY2624803 is a novel potent histamine H1 and 5HT-2A receptor modulator in the pipeline for treating insomnia.. |
879409-35-5 |
DC23510 |
LY2794193
Featured
LY2794193 is a highly potent and selective mGlu3 receptor agonist with Ki of 0.93 nM and EC50 of 47 nM, >100-fold selectivity over mGlu2 receptor.. |
2173037-97-1 |
DC10815 |
LY2795050
Featured
LY2795050 is a novel selective κ-opioid Receptor (KOR) antagonist (IC50=0.72 nM) and has the potential as a PET tracer to image KOR in vivo. |
1346133-08-1 |
DC7035 |
Merestinib(LY2801653 dihydrochloride)
Featured
LY2801653 2HCl is a potent, orally bioavailable, small-molecule inhibitor of c-MET kinase(Ki= 2 nM). |
1206801-37-7 |
DC8586 |
LY2801653
Featured
LY2801653 is a potent, orally bioavailable, small-molecule inhibitor of c-MET kinase(Ki= 2 nM). |
1206799-15-6 |
DC22595 |
LY2857785
LY2857785 is a potenrt, reversible and ATP-competitive CDK9 inhibitor with IC50 of 11 nM, also inhibits CDK8 (IC50=16 nM) and weakly inhibits CSK7 (IC50=246 nM). |
1619903-54-6 |
DC22312 |
LY2940094
Featured
LY2940094 is a potent and selective nociceptin receptor antagonist which inhibits excessive feeding behavior in rodents. |
1307245-86-8 |
DC21340 |
LY 2979165
LY2979165 (MP-101) is the alanine prodrug of LY2812223, a selective orthosteric mGlu2 receptor agonist. |
311385-35-9 |
DC23688 |
LY-3000328
Featured
LY 3000328 is a potent and selective Cathepsin S (Cat S) inhibitor with IC50s of 7.7 and 1.67 nM for hCat S and mCat S, respectively. |
1373215-15-6 |
DC23718 |
LY305
LY305 (LY-305) is a non-steroidal selective androgen receptor modulator (SARM) with Ki of 2.03 nM, demonstrates potent agonist activity in the aforementioned C2C12 cellular assay (EC50=0.499 nM). |
1430230-83-3 |
DC21259 |
LY 3130481
Featured
LY3130481 (CERC611) is a potent, selective, noncompetitive TARP γ8-associated AMPA receptors with IC50 of 65.3 nM (GluA1/TARP γ-8), with no activity for γ-2 (cerebellum) or other TARP members. |
1610802-47-5 |
DC12507 |
LY3143921
LY3143921 (LY-3143921) is an orally available, potent, selective inhibitor of Cdc7 kinase inhibitor, inhibits CDC7/DBF4 I and pMCM2 (S53) with IC50 values of 3.3 nM and 290 nM, respectively.. |
1627696-53-0 |
DC20262 |
LY3154207
Featured
LY3154207 is a potent and selective dopamine receptor D1 positive allosteric modulator for the treatment of Parkinson's disease dementia. |
1638667-79-4 |
DC21253 |
N-(3-((4aR,7aS)-2-amino-6-(5-fluoropyrimidin-2-yl)-4a,5,6,7-tetrahydropyrrolo[3,4-d][1,3]thiazin-7a(4H)-yl)-4-fluorophenyl)-5-methoxypyrazine-2-carboxamide
Featured
LY3202626 is a small molecule non-selective BACE1 inhibitor, causes dose-dependent reductions in CSF and plasma Aβ concentrations, shows potential for the treatment of Alzheimer's disease.. |
1628690-73-2 |
DC22784 |
LY-345899
Featured
LY-345899 (LY345899) is a novel potent, cytoplasmic and mitochondrial methylenetetrahydrofolate dehydrogenase MTHFD1 and MTHFD2 inhibitor with IC50 of 96 nM and 663 nM, respectively; MTHFD2 is a novel target for drug development. |
10538-99-5 |
DC6305 |
LY364947
Featured
LY364947 is a potent ATP-competitive inhibitor of TGFβR-I with IC50 of 59 nM, shows 7-fold selectivity over TGFβR-II. |
396129-53-6 |
DC23829 |
LY379196
LY379196 is a highly specific PKCβ inhibitor with IC50 of 30-50 nM for PKCβI and PKCβII, displays >10-fold selectivity of PKCα, δ, η, and γ (>600 nM). |
737736-10-6 |
DC23597 |
LY-404187
LY-404187 is a potent, selective, positive allosteric modulator of AMPA receptor (AMPAR) with EC50 of 1.3 uM. |
211311-95-4 |
DC22435 |
LY487379
Featured
LY-487379 is a potent, selective positive allosteric modulator of mGluR2 (EC50=0.27 uM) without activity at mGluR3; shows no intrinsic agonist or antagonist activity at hmGluR2, markedly potentiates glutamate-stimulated [35S]GTPgammaS binding at hmGluR2; potentiates synaptically evoked mGluR2 responses in rat hippocampal slices, modulates excitatory synaptic transmission in the rat globus pallidus. |
353231-17-1 |
DC22420 |
LY-487379 hydrochloride
LY-487379 is a potent, selective positive allosteric modulator of mGluR2 (EC50=0.27 uM) without activity at mGluR3. |
353229-59-1 |
DC23636 |
LY-503430
LY-503430 is a novel AMPA receptor (AMPAR) potentiator that selectively enhances glutamate-induced calcium influx into HEK293 cells transfected with human GLUA1, GLUA2, GLUA3, or GLUA4 AMPA receptors with EC50 of 0.1-4 uM. |
625820-83-9 |
DC21260 |
LY-83583
LY-83583 is an inhibitor of soluble guanylate cyclase (sGC) and of cGMP production, inhibits sGC in human platelets with IC50 of 2 uM. |
91300-60-6 |
DC23020 |
Lycobetaine(Ungeremine)
Featured
Lycobetaine(Ungeremine) is a potential biofungicide against Penicillium roqueforti and Aspergillus niger. |
2121-12-2 |
DC24081 |
Lyn-IN-1 (Synonyms: Bafetinib analog)
Featured
Lyn-IN-1 is a potent and selective dual Bcr-Abl/Lyn inhibitor.. |
887650-05-7 |
DC20440 |
LYPLAL1-IN-11
LYPLAL1-IN-11 is a potent, selective, covalent inhibitor of lysophospholipase-like 1 (LYPLAL1) with IC50 of 6 nM. |
1966129-74-7 |
DC21262 |
LYS228
LYS228 is a novel potent monobactam that shows potent activity against carbapenem-resistant isolates of Enterobacteriaceae with MIC90 of 2 ug/ml. |
1810051-96-7 |
DC12235 |
LysoPC(14:0/0:0)
Featured
LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. |
20559-16-4 |
DC23382 |
L-α-Hydroxyglutaric acid disodium salt
L-α-Hydroxyglutaric acid disodium salt (L-2-Hydroxyglutarate. |
63512-50-5 |
DC8478 |
M 344
Featured
M 344 enhances the sensitivity of human squamous carcinoma cells to radiation and promotes cell cycle arrest and apoptosis in human endometrial cancer and ovarian cancer cells (ED50 = 2.3 μM). |
251456-60-7 |
DC22728 |
M-110
M-110 is a potent, selective inhibitor of PIM kinase family with preference for PIM-3 with IC50 of 0.047, 2.5 and 2.5 uM for PIM3, PIM1 and PIM2, respectively. |
1395048-49-3 |
DC21264 |
M4284
M4284 (M-4284) is a high-affinity biphenyl mannoside FimH inhibitor with HAI of 16 nM in hemagglutination assay. |
1373346-85-0 |
DC21265 |
M-525
M-525 is a first-in-class, highly potent, irreversible small-molecule inhibitor of the menin-MLL interaction with binding IC50 of 3.3 nM in FP assays. |
2173582-08-4 |
DC21339 |
MAC1
MAC1 (Monastrol Antagonizing Compound 1) is a small molecule that can rescue spindle bipolarity in cells lacking Eg5 activity. |
325970-42-1 |
DC21266 |
MAC13772
MAC13772 is a potent inhibitor of BioA with an IC50 of 250 nM, a novel antibacterial inhibitor that selectively inhibits PABA biosynthesis in M tuberculosis.. |
4871-40-3 |
DC21267 |
MAC168425
MAC168425 is a novel antibacterial inhibitor that interferes with glycine metabolism in E coli.. |
2138-33-2 |
DC21268 |
MAC173979
MAC173979 is a novel time-dependent inhibitor of p-aminobenzoic acid biosynthesis with IC50 of 30 uM, represents the first PABA biosynthesis inhibitor with activity against Gram-negative bacteria.. |
41501-64-8 |
DC20269 |
mAChR-IN-1
Featured
mAChR-IN-1 is a potent muscarinic cholinergic receptor(mAChR) antagonist with IC50 of 17 nM.. |
119391-56-9 |
DC9922 |
Macranthoidin B
Macranthoidin B is a major bioactive saponin in rat plasma after oral administration of extraction of saponins from Flos Lonicerae. |
136849-88-2 |
DC9693 |
Madrasin
Featured
Madrasin inhibits pre-mRNA splicing in vitro and modify splicing of endogenous pre-mRNA. |
374913-63-0 |
DC8125 |
ETH 4030(Magnesium ionophore III)
Featured
Magnesium ionophore III is an onophore used in solvent polymeric membrane electrodes for the assay of Mg2+ activities in blood serum in vitro. |
119110-38-2 |
DC11215 |
MAI-150
MAI-150 is a peptidomimetic inhibitor of APC-Asef interaction, blocks colorectal cancer migration.. |
2143041-32-9 |
DC11201 |
MAI-400
MAI-400 (MAI400) is a novel peptide inhibitor of APC-Asef interaction with Kd of 12 nM and IC50 of 0.25 uM. |
|
DC23792 |
MAL3-101
MAL3-101 is a Hsc70 modulator that inhibits Hsp70 ATPase activity, exhibits antiproliferative activity in breast cancer cells SK-BR-3 with IC50 of 27 uM. |
912361-26-3 |
DC22143 |
MALAT1-IN-1
Featured
MALAT1 inhibitor 5 (Malat1 inhibitor 5) is a selective small molecule targeting of Metastasis-associated lung adenocarcinoma transcript 1 (Malat1/MALAT1 mouse/human), a highly conserved long non-coding RNA; does not affect Neat1 lncRNA levels. |
827327-28-6 |
DC12536 |
Malic Enzyme inhibitor ME1
Featured
Malic Enzyme inhibitor ME1 (ME1) is a small molecule inhibitor of Malic Enzyme (ME1) with IC50 of 0.15 uM, suppresses growth of human CRC cells in vitro, with little effect on normal rat intestinal epithelial cells.. |
522649-59-8 |
DCAPI1277 |
Malotilate
Malotilate |
59937-28-9 |
DC20141 |
Maltitol
Featured
Maltitol is a sugar alcohol used as a sugar substitute. It has 75-90% of the sweetness of sucrose (table sugar) and nearly identical properties. Maltitol may also be used as a plasticizer in gelatin capsules, as an emollient, and as a humectant. |
585-88-6 |
DC12138 |
Maltohexaose (Amylohexaose)
Maltohexaose is a natural saccharide, and can be produced from amylose, amylopectin and whole starch. |
34620-77-4 |
DC12157 |
Maltopentaose (Maltopentose)
Maltopentaose is the shortest chain oligosaccharide that can be classified as maltodextrin and is also used in a study to investigate glycation and phosphorylation of α-lactalbumin. |
34620-76-3 |
DC23814 |
MAP4K4-IN-17
Featured
MAP4K4-IN-17 is a potent and highly selective MAP4K4 inhibitor with IC50 of 14.9 nM, showes improved overall drug-like properties compared to PF-06260933. |
1811510-58-3 |
DC21916 |
MAP4K4-IN-37
MAP4K4-IN-37 is a potent, selective, orally active inhibitor of serine-threonine kinase MAP4K4 with IC50 of 0.4 nM. |
2089334-01-8 |
DC20442 |
MAP4K4-IN-44
MAP4K4-IN-44 is a potent, moderately selective small molecule MAP4K4 inhibitor with IC50 of 5 nM in LC3K assay, demonstrates favorable in vivo bioavailability in mouse.. |
1623464-28-7 |
DC21857 |
Mapracorat
Mapracorat (ZK 245186) is a potent, selective and non-steroid glucocorticoid receptor (GR) agonist with binding Ki of 1.9 nM. |
887375-26-0 |
DC4217 |
Maraviroc
Featured
Maraviroc (Selzentry, UK-427857, Celsentri) is a CCR5 antagonist for MIP-1α, MIP-1β and RANTES with IC50 of 3.3 nM, 7.2 nM and 5.2 nM, respectively. |
376348-65-1 |
DC21269 |
Marbostat-100
Marbostat-100 is a potent, selective HDAC6 inhibitor with Ki of 0.7 nM, displays >200-fold selectivity over HDAC1-5, and HDAC7-10. |
1876450-69-9 |
DC8909 |
Maribavir
Featured
Maribavir(GW257406X; BW1263W94; 1263W94) inhibits HCMV replication is by inhibition of an HCMV encoded protein kinase enzyme called UL97 or pUL97. |
176161-24-3 |
DC10639 |
Marinopyrrole A (Maritoclax)
Marinopyrrole A (Maritoclax) is a selective Mcl-1 antagonist. It binds to Mcl-1, but not Bcl-XL, and targets Mcl-1 for proteasomal degradation. Maritoclax disrupts the interaction between Bim and Mcl-1 with an IC50 of 10.1 μM. |
1227962-62-0 |
DC22297 |
Marmesin
Featured
Marmesin is a coumarin originally isolated from the mature bark of A. marmelos. |
13849-08-6 |
DC20883 |
Maropitant citrate
Maropitant citrate (Cerenia) is a selective neurokinin 1 receptor (NK1) antagonist for prevention of vomiting due to motion sickness in dogs.. |
862543-54-2 |
DC20443 |
MARPIN
MARPIN is a novel ATR-Chk1 pathway inhibitor that inhibits hydroxyurea (HU)-induced phosphorylation of Ser345 on Chk1 with IC50 of 7.7 uM. |
848675-17-2 |
DC10062 |
MBP146-78
Featured
MBP146-78 inhibits the growth of Eimeria spp. both in vitro and in vivo. |
188343-77-3 |
DC12094 |
MBQ-167
MBQ-167 is a dual Rac/Cdc42 inhibitor, with IC50s of 103 nM for Rac 1/2/3 and 78 nM for Cdc42 in MDA-MB-231 cells, respectively. |
2097938-73-1 |
DC7193 |
MBX-2982
Featured
MBX-2982 is a selective, orally-available GPR119 agonist for the treatment of type 2 tiabetes. |
1037792-44-1 |
DC10872 |
MBX-4132
Featured
MBX-4132 a trans translation inhibitor by binding to the bacterial ribosome. |
2286411-30-9 |
DC21270 |
MC-1575
MC-1575 is a potent and selective class IIa HDAC inhibitor with IC50 of 440 nM for maize HD1-A, displays >70-fold selectivity over HD1-B. |
|
DC12527 |
MC180295
Featured
MC180295 (MC-180295, MC 180295) is a novel potent, highly selective CDK9 inhibitor with IC50 of 5 nM, displays >22-fold selectivity over other CDKs. |
2237942-08-2 |
DC23370 |
MC2884
MC2884 is a novel hybrid, dual HAT/EZH2 inhibitor with IC50 of 3.27, 8.35 and 4.56 uM for CBP, KAT5 and p300, respectively. |
330657-42-6 |
DC11358 |
CPP32 Fluorogenic Substrate III
Mca-DEVDAPK(Dnp)-OH is a substrate for caspase-3. |
189696-20-6 |
DC8550 |
MCB-613
Featured
MCB-613 is a novel and potent stimulator of p160 steroid receptor coactivators (SRCs). It is a Pan-SRCs stimulator. |
1162656-22-5 |
DC23706 |
Netoglitazone(MCC 555)
Featured
Netoglitazone, also known as isaglitazone and MCC-555, is an agent belonging to the glitazone class of antidiabetic agents with antihyperglycemic activity. Netoglitazone exerts both peroxisome proliferator-activated receptor (PPAR) alpha and gamma agonist activity. Netoglitazone decreases bone formation and increases marrow adipocyte formation in vivo.MCC 555 (Isaglitazone. |
161600-01-7 |
DC26109 |
MCL0129 tetrahydrochloride
Featured
MCL0129 is a selective, potent melanocortin-4 receptor (MC4R) antagonist with Ki of 7.9 nM, without affinity for MC1 and MC3. |
574001-66-4 |
DC26085 |
MCL0129
MCL0129 is a selective, potent melanocortin-4 receptor (MC4R) antagonist with Ki of 7.9 nM, without affinity for MC1 and MC3. |
768357-45-5 |
DC22643 |
Mcl1-IN-2
Mcl1-IN-2 is an Mcl-1 inhibitor without a reported IC50 value.. |
292057-76-2 |
DC20444 |
Mcl-1-Puma inhibitor 8
Mcl-1-Puma inhibitor 8 is a small-molecule dual-acting compound that targets the apoptotic Mcl-1-PUMA interface with Ki of 0.3 uM (Mcl-1, FPA), reduces multiple cancer cells and inhibits PUMA-mediated apoptosis. |
678158-55-9 |
DC10353 |
MCOPPB triHydrochloride
MCOPPB 3Hcl is a nociceptin receptor agonist with pKi of 10.07; weaker activity at other opioid receptors. |
1108147-88-1 |
DC23820 |
MCP110
Featured
MCP110 is a potent Ras/Raf-1 interaction inhibitor. |
521310-51-0 |
DC23644 |
MCT1-IN-4a
MCT1-IN-4a is a potent, selective monocarboxylate transporter 1 (MCT1) inhibitor with IC50 of 90 nM. |
1448314-00-8 |
DC7841 |
MDA 19
MDA 19 is a selective human CB2 receptor agonist with Ki of 43.3 nM. |
1048973-47-2 |
DC12581 |
MDI-2268
Featured
MDI-2268 (MDI2268) is a small-molecule, in vivo-active inhibitor of plasminogen activator inhibitor type-1 (PAI-1), demonstrates excellent pharmacokinetics, potent activity against vitronectin-bound PAI-1 in vivo, and efficacy in murine model of venous thrombosis. |
1609176-50-2 |
DC7743 |
Mdivi-1
Featured
Mdivi-1 is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 μM. |
338967-87-6 |
DC10569 |
MDK1088(T.cruzi Inhibitor)
Featured
MDK-1088, also known as T.cruzi Inhibitor, is a Trypanosoma cruzi inhibitor. MDK-1088 has CAS#1350920-22-7 . The last 4 digit f CAS# was used in its name. |
1350920-22-7 |
DC10573 |
MDK34597 (PI3K inhibitor)
Featured
MDK34597 is a PI3K inhibitor.MDK34597 is an analog of PI-103 and acts as a dual PI3K/mTOR Inhibitor. |
371934-59-7 |
DC10572 |
MDK35833(Oct3/4-inducer-1)
Featured
MDK35833, also known as Oct3/4-inducer-1, is a potent Oct3/4-inducer. |
1016535-83-3 |
DC24209 |
MDK7229(MD2-IN-1)
Featured
MDK7229, also known as MD2-IN-1 is a MD2 (Myeloid differentiation protein 2) inhibitor. |
111797-22-9 |
DC10570 |
MDK74978(Multi-kinase inhibitor)
Featured
MDK74978, also known as Multi-kinase inhibitor I, is a Multi-kinase inhibitor. MDK74978 has CAS#778274-97-8. The last 5 digit was used in its name. |
778274-97-8 |
DC10571 |
MDK-8582(Hnps-PLA Inhibitor)
Featured
MDK-8582, also known as Hnps-PLA Inhibitor, is an nhibitor of human nonpancreatic secretory Phospholipase A (hnps-PLA). |
185298-58-2 |
DC10650 |
MDVN1003
Featured
MDVN1003 is a potent inhibitor of BTK amd PI3K delta. |
2058116-52-0 |
DC23739 |
Meayamycin
Meayamycin is an analogue of FR901464 that binds to the splicing factor 3b (SF3b) complex and inhibits pre-mRNA splicing, shows picomolar antiproliferative activity against various cancer cell lines and multidrug-resistant cells.. |
933474-26-1 |
DCAPI1081 |
Mecarbinate
Mecarbinate |
15574-49-9 |
DC9035 |
Meclofenoxate HCl
Meclofenoxate hydrochloride, an ester of dimethylethanolamine (DMAE) and 4-chlorophenoxyacetic acid (pCPA), has been shown to improve memory, have a mentally stimulating effect, and improve general cognition. |
3685-84-5 |
DC20446 |
Mefuparib hydrochloride(CVL218)
Featured
Mefuparib(CVL218) hydrochloride is a potent, highly selective, competitive PARP1/2 inhibitor with IC50 of 3.2/1.9 nM, respectively.CVL218 was more potent than Remdesivir in blocking Coronavirus infection of cells and equally as potent as Remdesivir in blocking replication of virus once it has entered the cells. |
1449746-00-2 |
DC7461 |
Meisoindigo
Featured
Meisoindigo(Natura-α; N-Methylisoindigotin; Dian III), a derivative of Indigo naturalis, might induce apoptosis and myeloid differentiation of acute myeloid leukemia (AML). |
97207-47-1 |
DC26032 |
Melagatran
Melagatran is a synthetic, small-peptide direct thrombin inhibitor with anticoagulant activity. |
159776-70-2 |
DC11353 |
MIF-1
Melanocyte-stimulating hormone release-inhibiting factor (MSH-R-IF) is a hypothalamic tripeptide that binds to rat striatum (Kd = 4.69 nM) and has diverse biological activities. |
2002-44-0 |
DC8311 |
Meleagrin
Meleagrin is an antibiotic derived from a deep ocean, penicillin-producingP. chrysogenum. |
71751-77-4 |
DC21274 |
Melflufen
Melflufen (Melphalan flufenamide, J1) is a novel dipeptide and alkylating prodrug of melphalan, inhibits angiogenesis in vitro and in vivo. |
380449-51-4 |
DC21917 |
MELK inhibitor 17
MELK inhibitor 17 is a potent, selective MELK inhibitor with Ki/IC50 of 0.39/3 nM, >100-fold selectivity over CHK1, CAMKK2, NUAK1 and ERK2. |
2095596-44-2 |
DCAPI1316 |
Meloxicam (Mobic)
Meloxicam (Mobic) |
71125-38-7 |
DC22506 |
Merck60
Featured
Merck60 (BRD 6929, Compound-60) is a potent, selective and brain-penetrant inhibitor of HDAC1 and HDAC2 with IC50 of 1 nM and 8 nM respectively. |
849234-64-6 |
DCAPI1395 |
Meropenem
Meropenem |
96036-03-2 |
DC20130 |
meso-Erythritol
Featured
meso-Erythritol is a sugar alcohol that occurs naturally in a variety of foods (e.g., pear, watermelon), is 60-80% as sweet as sucrose, and is an approved low-calorie sweetener food additive. |
149-32-6 |
DCAPI1322 |
Mestranol
Mestranol |
72-33-3 |
DC12327 |
Metadoxine
Metadoxine blocks adipocyte differentiation in association with inhibition of the protein kinase A-cAMP response element binding protein (PKA-CREB) pathway. |
74536-44-0 |
DC22157 |
Metarrestin
Featured
Metarrestin (ML246) is a specific inhibitor of perinuclear compartment (PNC), disrupts PNCs in PC3M-GFP-PTB cells with IC50 of 0.39 uM, specifically binds eEF1A2. |
1443414-10-5 |
DC9563 |
Metaxalone
Metaxalone(AHR438;NSC170959) is a muscle relaxant used to relax muscles. |
1665-48-1 |
DC23326 |
Metesind glucuronate
Metesind glucuronate (AG 331. |
157182-23-5 |
DCAPI1018 |
Metformin HCl(Glucophage)
Metformin HCl(Glucophage) |
1115-70-4 |
DCAPI1174 |
Methacycline HCl (Physiomycine)
Methacycline HCl (Physiomycine) |
3963-95-9 |
DC12309 |
MethADP (Adenosine 5'-(α,β-methylene)diphosphate)
MethADP is a specific CD73 inhibitor. |
3768-14-7 |
DC8943 |
Methimazole
Methimazole(Tapazole, Northyx) is an antithyroid medicine. |
60-56-0 |
DC8989 |
Methocarbamol
Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms. |
532-03-6 |
DC9149 |
Methotrexate
Methotrexate(WR19039; CL14377) can interfere with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells. |
59-05-2 |
DC23215 |
Methoxy-PEPy
Methoxy-PEPy is a potent, selective mGlu5 receptor antagonist with IC50 of 1 nM. |
524924-76-3 |
DC10575 |
Methyl 13-cis-4-Oxoretinoate
Featured
Methyl 13-cis-4-Oxoretinoate is a bioactive chemical. |
71748-57-7 |
DC20131 |
Methyl 3,4-dihydroxybenzoate
Featured
Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester;Methyl protocatechuate) is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect. |
2150-43-8 |
DC8616 |
S-(5'-Adenosyl)-L-methionine chloride(SAM)
Featured
Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). |
86867-01-8 |
DC20447 |
Methyl Gerfelin
Methyl Gerfelin (M-GFN) is an osteoclastogenesis inhibitor (IC50=2.8 uM) through the competitive inhibition of glyoxalase I (GLO1) with Ki of 0.23 uM. |
700870-56-0 |
DC20448 |
Methyliodobikinin
Methyliodobikinin is a potent bikinin-like inhibitor targeting GSK3/Shaggy-like kinase, shows improved cell permeability, highly potent in vivo although it had lower activity in vitro. |
1186336-04-8 |
DCAPI1359 |
Methylprednisolone
Methylprednisolone |
83-43-2 |
DC9417 |
Methylproamine
Methylproamine is a DNA-binding radioprotector which, on the basis of published pulse radiolysis studies, acts by repair of transient radiation-induced oxidative species on DNA. |
188247-01-0 |
DC20015 |
Metixene hydrochloride hydrate
Metixene hydrochloride hydrate is an anticholinergic antiparkinsonian agent, potently inhibits binding of quinuclidinyl benzilate (QNB) to the muscarinic receptor in rat brain cortical tissue, with an IC50 of 55 nM and a Kd of 15 nM. |
7081-40-5 |
DCAPI1095 |
Metolazone (Zaroxolyn)
Metolazone (Zaroxolyn) |
17560-51-9 |
DC20191 |
Metronidazole Benzoate;Benzoyl metronidazole
Metronidazole Benzoate is the benzoate ester of metronidazole, a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. |
13182-89-3 |
DC23468 |
MF266-1
MF266-1 is a potent, selective prostaglandin E receptor subtype 1 (EP1) antagonist with Ki of 3.8 nM, displayes a relatively good selectivity over other prostanoid receptors.. |
848188-18-1 |
DC22145 |
MF-766
Featured
MF-766 (MF766) is a highly potent and selective EP(4) antagonist with binding Ki of 0.23 nM, displays no significant affinity (>7000-fold selectivity) against other PG receptors (IC50>1500 nM); behaved as a full antagonist with an IC50 of 1.4 nM (shifted to 1.8 nM in the presence of 10% HS) in the functional assay; exhibits blockade of inhibition of TNFa-induced IP10 release by the specific EP4 agonist L-000902688 (IC50=9.5 nM); demonstrates potency and efficacy of in the rat AIA model measuring inhibition of paw swelling. |
1050656-06-8 |
DC23707 |
MFA-1
MFA-1 (Merck FXR agonist 1) is a potent, synthetic FXR agonist with EC50 of 16.9 nM in coactivator recruitment assays, displays 500-fold more potent than CDCA. |
139755-30-9 |
DC11211 |
MFN2 agonist B-A l
MFN2 agonist B-A/l is a mall-molecule mimics of the peptide-peptide interface of MFN2, allosterically activates MFN2 and promotes mitochondrial fusion with EC50 of 3 nM. |
2230047-87-5 |
DC21918 |
MGR1
MGR1 is a ROS-generating probe that can generate ROS (reactive oxygen species) in different mammalian cells, causes concentration-dependent cell death in HEK293T with IC50 of 5.7 uM.. |
|
DC22147 |
MGV354 R-form
MGV354 is a novel potent, selective soluble Guanylate Cyclase (sGC) activator, lowers intraocular pressure (IOP) in preclinical models of glaucoma.. |
1852495-87-4 |
DC22146 |
MGV354
Featured
MGV354 is a novel potent, selective soluble Guanylate Cyclase (sGC) activator, lowers intraocular pressure (IOP) in preclinical models of glaucoma.. |
1852495-86-3 |
DC8074 |
MHY1485
Featured
MHY1485 is mTOR activator that potently inhibits autophagy by suppression of fusion between autophagosomes and lysosomes. |
326914-06-1 |
DC23290 |
MI 219
MI 219 is a potent, specific MDM2-p53 inhibitor with Ki of 5 nM, >10,000-fold selective for MDM2 over MDMX. |
908027-55-4 |
DC22148 |
MI-1481
MI-1481 (MI1481) is a highly potent inhibitor of the menin-MLL1 interaction with IC50 of 3.6 nM, 10-fold increase in inhibitory activity over MI-463 and MI-503. |
1887178-64-4 |