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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC34753 | Sulfo-EGS Crosslinker |
Sulfo-EGS Crosslinker, or Ethylene glycol bis(sulfosuccinimidylsuccinate), is a water soluble homobifunctional crosslinker. Sulfo-EGS Crosslinker can be used to label cell surface proteins as the molecule is not cell membrane permeable.
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| DC34740 | Sulfo-LC-SPDP Crosslinker |
Sulfo-LC-SPDP Crosslinker, or Sulfosuccinimidyl 6-(3'-[2-pyridyldithio]-propionamido)hexanoate, is a cleavable, water soluble, amino and thiol (sulfhydryl) reactive heterobifunctional protein crosslinker. The "long chain" Sulfo-LC-SPDP crosslinking reagent has a 15.7 angstrom spacer arm, and is the water soluble analog of LC-SPDP crosslinker.
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| DC34732 | LC-SPDP Crosslinker |
LC-SPDP Crosslinker, also known as SPDP-C6-NHS ester, is a cleavable, water insoluble, amino and thiol (sulfhydryl) reactive heterobifunctional crosslinking reagent. The "long chain" LC-SPDP crosslinking reagent has a 15.7 angstrom spacer arm, compared to the shorter 6.8 angstrom spacer arm version of SPDP crosslinker. Often, due to steric hindrances, it is desirable to empirically test which of the two versions will work best in your specific application. LC-SPDP Crosslinker is useful for making Antibody Drug Conjugates (ADCs).
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| DC34665 | Monensin |
Monensin is an antiprotozoal agent produced by Streptomyces cinnamonensis. Monensin is a sodium and proton selective ionophore and is widely used as such in biochemical studies, particularly as an anti-tumor agent. It has an inhibitory effect on the Wnt/β-catenin signaling cascade, which may be useful when the cascade is aberrantly activated in cancer cells. Monensin is a prospective anticancer drug for therapy of neoplasia with deregulated Wnt signaling.
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| DC34605 | aPKCI |
aPKC-I is an inhibitor of atypical protein kinase C (aPKC ) which inhibits both PKCζ and PKCι with high specificity and prevents VEGF-induced endothelial permeability in cell culture and in vivo, thereby blocking ischemia-reperfusion (IR)-induced permeability.
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| DC34578 | Monosulfuron |
Monosulfuron is an herbicide.
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| DC34556 | p Tolylmaleimide |
p-Tolylmaleimide is a water channel inhibitor which binds to aquaporin Z (AqpZ).
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| DC34554 | 3F-8 |
3F8 is a selective and potent GSK-3? inhibitor.
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| DC34538 | TerpendoleE |
Terpendole E is an atypical L5 site inhibitor.
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| DC34529 | Benzomalvin-A |
Benzomalvin A is a filamentous fungal secondary metabolite.
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| DC34526 | MitoPeroxidase 2 |
MitoEbselen-2, also known as MitoPeroxidase-2, is a radiation mitigator which reduces lipid hydroperoxides and prevents apoptotic cell death. When administered 24 hours postirradiation, MitoEbselen-2 was shown to increase the survival of mice exposed to whole body γ-irradiation.
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| DC34458 | EPPS |
EPPS is a rescuer of A? aggregation and behavioural deficits, binding to A? aggregates and converting them into monomers.
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| DC34449 | Dofequidar fumarate |
Dofequidar fumarate is a potent inhibitor of MDR-1.
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| DC34442 | BAY32-5915 |
BAY32-5915 is an IKKalpha inhibitor.
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| DC34411 | SC-58125 |
SC-58125 is a selective cyclooxygenase 2 (COX-2) inhibitor.
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| DC34401 | NTE-122 |
NTE-122 is a potent, selective and competitive inhibitor of Acyl-CoA:cholesterol acyltransferase (ACAT).
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| DC34368 | DHQ |
DHQ is an inducer of ATPase activity of Herpes Simplex Virus thymidine kinase.
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| DC34323 | WST-1 |
WST-1 is a chromogenic indicator for NADH.
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| DC34318 | NSC756093 |
NSC756093 is the first inhibitor of the GBP1:PIM1 interaction.
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| DC34317 | Arylquin-1 |
Arylquin-1 is a secretagogue of prostate apoptosis response-4 (Par-4). It acts by displacing Par-4 from vimentin for secretion and triggering the efficient paracrine apoptosis of diverse cancer cells.
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| DC34301 | SAFit2 |
SAFit2 is a selective inhibitor of the ?FK506-binding protein 51 (FKBP51).
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| DC34291 | alphaSYN-IN-NAB2 |
alphaSYN-IN-NAB2 is an inhibitor of α-synuclein mutations. It acts by reversing the α-synuclein-induced pathological phenotype in Parkinson's disease cortical neurons and promoting E3 ubiquitin ligase Rsp5/Nedd4-dependent endosomal transport..
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| DC34241 | TASIN-1 Hydrochloride |
TASIN-1 Hydrochloride is a truncated APC selective inhibitor. It acts by selectively killing colorectal cancer cells that express truncated APC by reducing cellular cholesterol levels and inducing apoptotic cell death through the ER stress/ROS/JNK signaling in colon cancer cells.
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| DC34236 | p-BrBzGSH(Cp)2 |
p-BrBzGSH(Cp)2 is an inhibitor of glyoxylase 1 (GLO1). It acts by increasing DNA-AGEs, stimulating RAGE expression, and inhibiting brain tumor growth in orthotopic mouse models.
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| DC34225 | Aminoluciferin |
Aminoluciferin is a luciferin derivative as functional bioluminogenic substrate.
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| DC34221 | PF2562 |
PF2562 is a non-catechol dopamine 1 receptor agonist. Dopamine D1 receptors are implicated in numerous neuropharmacological and neurobiological functions. For example, D1 receptors are involved in different types of memory function and synaptic plasticity.
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| DC34202 | Phosphoramidon disodium |
Phosphoramidon disodium is a neutral endopeptidase (neprilysin) inhibitor. It blocks degradation of amyloid β peptides and endothelin converting enzyme (ECE).
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| DC34198 | (-)-Pironetin |
Pironetin is a natural α-tubulin-binding agent with potent antiproliferative activity. It acts by inhibiting cell division by forming a covalent adduct with α-tubulin.
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| DC34185 | 5-TAMRA SE |
5-TAMRA SE is a fluorescent amino-group-reactive probe for DNA and RNA.
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| DC34134 | DL-Phenylephrine hydrochloride |
DL-Phenylephrine HCl is a selective alpha1-adrenergic receptor agonist.
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