DCC4058 |
Pdi-in-p1 |
Protein disulfide isomerase (PDI) inhibitor |
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DCC4059 |
Pd-l1 Degrader F4 |
Novel PD-L1 degrader, showing 66.99% degradation activity at 20 μM with no calcium blocking effect, strengthening the T cell-mediated killing of tumor cells |
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DCC4060 |
Pd-l1 Degrader P22 |
Novel PROTAC dual inhibitor and degrader of PD-L1, inhibiting PD-1/PD-L1 interaction with IC50 of 39.2 nM in an HTRF binding assay |
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DCC4061 |
Pd-l1 Inhibitor L7 |
Novel Potent PD-L1 Inhibitor (IC50 1.8 nM), binding to human PD-L1 (hPD-L1) with a KD value of 3.34 nM, without showing any binding to hPD-1, blocking PD-1/PD-L1 interaction with an EC50 value of 375 nM |
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DCC4062 |
Pdsinh-c01 |
Novel pendrin inhibitor, inhibiting Cl-/anion exchange mediated by mouse pendrin without affecting other major kidney tubule transporters |
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DCC4063 |
Peg-vtx |
Novel polyethylene glycol (PEG)-drug conjugate of Venetoclax, a Bcl-2 inhibitor, for treatment of acute myeloid leukemia (AML) |
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DCC4064 |
Pelorol |
Activator of SHIP-1 |
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DCC4065 |
pemedolac |
Cyclooxygenase Inhibitor and Prostagladin Synthase Inhibitor |
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DCC4066 |
Penb-l-glutamate |
Novel caged glutamate |
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DCC4067 |
Penclomedine |
Antineoplastic agent, alkylating and crosslinking DNA, resulting in DNA strand breaks and inhibition of DNA and RNA synthesis |
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DCC4068 |
Penicillic Acid |
Mycotoxin with antibiotic and carcinogenic activity |
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DCC4069 |
penicillin K |
Antibiotic, a natural penicillin, synthesized in vitro by incubating (S-octanoyl)glutathione, 6-APA and AT |
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DCC4070 |
Penindolone |
Novel potent and broad-spectrum anti-influenza A virus (anti-IAV) activities with low risk of inducing drug resistance |
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DCC4071 |
Pentamidine Dimesylate |
Inhibitor of calcium-dependent complex formation with p53 [(Ca)S100B-p53] in malignant melanoma (MM), restoring p53 tumor suppressor activity in vivo |
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DCC4072 |
Peptide 1018 |
Innate defense regulator, target stringent response-controlled virulence in a Pseudomonas aeruginosa murine cutaneous infection model |
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DCC4073 |
Peptide 4f |
ApoA-I/HDL mimetic peptide, efficiently crossing the blood-brain barrier and modulating amyloid beta distribution between brain and plasma |
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DCC4074 |
Peptide P9r |
Broad-spectrum virus- and host-targeting peptide, inhibiting coronaviruses and other respiratory viruses |
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DCC4075 |
Pergolide Mesylate |
Agonist of dopamine receptor subtypes D1 and D2 |
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DCC4076 |
Peridinin |
Exceptionally Potent and Membrane-Embedded Inhibitor of Bilayer Lipid Peroxidation |
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DCC4077 |
Perindopril |
Non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor |
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DCC4078 |
Pet-16 |
Novel allosteric inhibitor of E. coli Hsp70 (DnaK) and human Hsp70 proteins |
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DCC4079 |
Pex14-pex5 Inhibitor-5 |
First Inhibitor of PEX14-PEX5 Protein-Protein Interaction (PPI) with Trypanocidal Activity |
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DCC4080 |
Pf-03084014 |
Novel γ-secretase inhibitor |
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DCC4081 |
Pf-03671148 |
Dose dependent inhibitor of multiple fibrotic genes |
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DCC4082 |
Pf-04363467 Hydrochloride |
Selective dopamine D3/D2 receptor antagonist |
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DCC4083 |
Pf-04671536 Hydrochloride |
Novel potent and selective PDE8B/8A inhibitor |
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DCC4084 |
pf-04859989 |
Irriversible inhibitor of kynurenine amino transferase II (KAT II) |
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DCC4085 |
Pf-05109794 |
Novel selective hTRPV4 Antagonist (hTRPV4 IC50 49nM; rTRPV4 IC50 1,150nM) |
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DCC4086 |
Pf-05214030 |
Novel potent TRPV4 antagonist (hTRPV4 IC50 4nM; rTRPV4 IC50 27nM) |
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DCC4087 |
Pf-06371900 |
Novel potent and highly selective leucine rich repeat kinase 2 (LRRK2) inhibitor |
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