Cas No.: | 2138882-71-8 |
Chemical Name: | 4,6-dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine |
Synonyms: | KEA 1-97 |
SMILES: | N1=C(Cl)N=C(Cl)N=C1NC1=CC=C(C2=CC=C(F)C=C2)C=C1 |
Formula: | C15H9Cl2FN4 |
M.Wt: | 335.163 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | KEA1-97 (KEA 1-97) is a small molecule that disrupts the interaction of thioredoxin with caspase 3; activates caspases, and induces apoptosis without affecting thioredoxin activity, impairs triple-negative breast cancer cell survival; impairs in vivo breast tumor xenograft growth. |
References: | References 1. Anderson KE, et al. ACS Chem Biol. 2017 Oct 20;12(10):2522-2528. View Related Products by Target Caspase |