AZD0095|CAS 2750001-23-9|DC Chemicals

Cas No.:	2750001-23-9
Chemical Name:	AZD0095
Synonyms:	AZD0095
SMILES:	CC1=C(C(C)=NC2=NC(C)=NN12)O[C@@H]1CCN(C2C=CC(C3N=NC(CN4CCOCC4)=CC=3)=CC=2)C1
Formula:	C₂₇H₃₂N₈O₂
M.Wt:	500.595384597778
Purity:	98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

COA

Cat. No.	Product name	Field of application
DC72788	AZD0095	AZD0095 is a selective and orally active MCT4 inhibitor (IC50: 1.3 nM). AZD0095 effectively inhibits the tumor growth in NCI-H358 xenograft in combination with Cediranib.
DC11218	BAY-8002	BAY-8002 is a novel potent, selective, orally available monocarboxylate transporter 1 (MCT1) inhibitor (Kd=7.9 nM).
DC9263	AZD-3965	AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding affinity of 1.6 nM, is 6 fold selective over MCT2 and does not inhibit MCT4 at 10 μM.
DC7876	7ACC2	7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for inhibition of [14C]-lactate influx; new antitumor treatment targeting lactate transport in cancer cells.