| DC47561 |
MHY-1685
|
MHY-1685, a novel mammalian target of rapamycin (mTOR) inhibitor, provides opportunities to improve hCSC-based myocardial regeneration.
|
| DC11816 |
RapaLink-1
|
RapaLink-1 is a third-generation mTOR inhibitor that overcomes resistance to existing first- and second-generation inhibitors; blocks mTOR signaling of the F2108L mTOR and M2327I mTOR drug resistant mutants; RapaLink-1 is more potent mTOR inhibitor than rapamycin. |
| DC1006 |
OSI-027
|
OSI-027 is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM, respectively. |
| DC7210 |
LY-303511(Nv-128)
|
LY303511, an inactive analogue of LY294002, is a mTOR inhibitor that did not inhibit PI3-K. |
| DC7171 |
INK-128(Sapanisertib)
|
INK 128 is a potent and selective mTOR inhibitor with IC50 of 1 nM; >200-fold less potent to class I PI3K isoforms. |
| DC11866 |
AZD 3147
|
A potent, selective dual mTORC1 and mTORC2 inhibitor with enzyme IC50 of 1.5 nM. |
