Novel inhibitors | DC Chemicals

Cat. No.	Product name	CAS No.
DC22611	N6-[2-(4-Aminophenyl)ethyl]adenosine A non-selective agonist of Adenosine A3 receptor.	89705-21-5
DC22619	Rotigotine Featured A non-selective agonist of the dopamine D3 receptor (Ki=0.71 nM).	99755-59-6
DC22609	rac-Rotigotine hydrochloride A non-selective agonist of the dopamine D3 receptor (Ki=0.71 nM).	102120-99-0
DC22662	Carteolol A non-selective beta blocker used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and an antiglaucoma agent..	51781-06-7
DC23203	E4CPG Featured A non-selective group I/group II metabotropic glutamate receptor (mGluR) antagonist..	170846-89-6
DC11763	ABP 1 A nonselective inhibitor of UBL protein-activating E1 enzymes that forms covalent adducts with UBL proteins SUMO1, ubiquitin, Nedd8, ISG15, and GABARAP in the presence of ATP and E1 enzymes in vitro.	1482293-92-4
DC24159	(R)-Flurbiprofen A non-steroidal anti-inflammatory drug (NSAID).	51543-40-9
DC22769	Droloxifene A nonsteroidal selective estrogen receptor modulator (SERM) that shows 10- to 60-fold increased affinity for the estrogen receptor compared with Tamoxifen.	82413-20-5
DC21706	STX3451 A non-steroidal sulphamate analogue of 2-methoxyoestradiol (2ME2) and microtubule disruptor, shows anti-proliferative activity against NCI 60 cell lines with mean GI50 of 50 nM.	1623785-58-9
DC11919	Arimoclomol Featured A nontoxic heat shock protein (HSP) coinducer and potentiator of the heat shock response.	289893-25-0
DC11920	Arimoclomol maleate Featured A nontoxic, orally active heat shock protein (HSP) coinducer and potentiator of the heat shock response.	289893-26-1
DC24034	Coluracetam A nootropic agent that enhances high-affinity choline uptake.	135463-81-9
DC21342	MPT0L145 A nove potent, dual FGFR and PIK3C3 inhibitor with Kd of 0.53 nM for PIK3C3.
DC20550	SHP2 inhibitor 2 A nove potent, selective and reversible SHP2 inhibitor with Ki of 0.51 uM.	1799604-71-9
DC11523	Landipirdine A novel 5-HT receptor antagonist for the treatment of Parkinson's disease..	1000308-25-7
DC11793	UMB-32 A novel a potent, selective inhibitor of BRD4 with Kd of 550 nM, cellular IC50 of 724 nM.	1635437-39-6
DC23493	Ladarixin A novel allosteric, noncompetitive dual CXCR1/2 inhibitor that inhibits human polymorphonuclear leukocyte (PMN) migration to CXCL8 in vitro with IC50 of 0.7 nM.	849776-05-2
DC23467	Ladarixin sodium A novel allosteric, noncompetitive dual CXCR1/2 inhibitor that inhibits human polymorphonuclear leukocyte (PMN) migration to CXCL8 in vitro with IC50 of 0.7 nM.	865625-56-5
DC20706	AVN-211 A novel and highly selective 5-HT6 receptor small molecule antagonist with Ki of 2.34 nM.	1173103-84-8
DC22565	K-Ras G12C-IN-3 A novel and irreversible inhibitor of mutant K-ras G12C..	1629268-19-4
DC22572	K-Ras G12C-IN-2 A novel and irreversible inhibitor of mutant K-ras G12C..	1629267-75-9
DC22573	K-Ras G12C-IN-1 A novel and irreversible inhibitor of mutant K-ras G12C..	1629265-17-3