| DC20594 |
(R)-ZINC-3573
Featured
|
(R)-ZINC-3573 is a potent, selective agonist of the atypical opioid receptor MRGPRX2 (EC50=0.76 uM), showing little activity against 315 other GPCRs and 97 representative kinases. |
|
| DC9581 |
(S)-(+)-Rolipram |
(S)-(+)-Rolipram is a PDE4-inhibitor and an anti-inflammatory agent, less potent than its R enantiomer.
|
|
| DC26029 |
(S)-4CPG |
(S)-4CPG, also known as (S)-4-Carboxyphenylglycine, is a novel orally active metabotropic glutamate receptor 1 antagonist. |
|
| DC23811 |
(S)-BAY-293(BAY293 S-enantiomer) |
(S)-BAY-293 (BAY293 S-enantiomer) is the S-enantiomer of BAY-293 as a negative control compound.. |
|
| DC20595 |
(S)-FQI1 |
(S)-FQI1 is a small-molecule inhibitor of transcription factor LSF with IC50 of 0.93 uM, approximately 2-fold more active than the racemate FQI-1. |
|
| DC9368 |
(S)-Gossypol (acetic acid) |
(S)-Gossypol acetic acid is a inhibitor of Bcl-2, potently induce cell death in Jurkat cells overexpressing Bcl-2 (IC50, 18.1μM) or Bcl-xL (IC50, 22.9μM).
|
|
| DC20017 |
(S)-Mapracorat |
(S)-Mapracorat is a selective and less active glucocorticoid receptor agonist. |
|
| DC12085 |
(S)-Metolachor |
(S)-Metolachor, a derivative of aniline, is a major pesticide in use. |
|
| DC9137 |
Timolol Maleate
Featured
|
(S)-Timolol maleate, is a potent non-selective β-adrenergic receptor antagonist (Ki values are 1.97 and 2.0 nM for β1 and β2 receptor subtypes respectively). |
|
| DC24129 |
(S)-Willardiine |
(S)-Willardiine is a potent agonist of AMPA/kainate receptors with EC50 of 44.8 uM.. |
|
| DC26120 |
(Z)-4-hydroxy Tamoxifen
Featured
|
(Z)-4-hydroxy Tamoxifen is a major phase I metabolite of tamoxifen, a well-known estrogen receptor antagonist in breast but partial estrogen receptor agonist in endometrium. |
|
| DC10396 |
(Z)-Mutagenic Impurity of Tenofovir Disoproxil |
(Z)-Mutagenic Impurity of Tenofovir Disoproxil is a mutagenic impurity in tenofovir disoproxil fumarate. Tenofovir is an antiretroviral drug known as nucleotide analogue reverse transcriptase (NtART) inhibitor, which blocks reverse transcriptase, a crucia |
-Mutagenic Impurity of Tenofovir Disoproxil.gif)
|
| DC20577 |
Valemetostat
Featured
|
.Valemetostat is an antineoplastic agent. |
|
| DC20486 |
OxPAPC 2 |
. |
|
| DC20487 |
OxPAPC 3 |
. |
|
| DC20488 |
OxPAPC 4 |
. |
|
| DC20485 |
OxPAPC 1 |
. |
|
| DCQ-020 |
Oroxylin A
Featured
|
>98%,Standard References |
|
| DC55150 |
Gentiopicroside
Featured
|
Gentiopicroside, a naturally occurring iridoid glycoside, inhibits P450 activity, with an IC50 and a Ki of 61 µM and 22.8 µM for CYP2A6; Gentiopicroside has antianti-inflammatoryand antioxidative effects. |
|
| DC82022 |
Reserpine
Featured
|
Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2). |
|
| DC3135 |
Carumonam sodium |
0 |
|
| DC4150 |
Menotrophin
Featured
|
0 |
|
| DC20187 |
1, 10-Phenanthroline monohydrate;Phenanthroline monohydrate |
1,10-Phenanthroline is a classic chelating bidentate ligand for transition metal ions that has played an important role in the development of coordination chemistry. It is an inhibitor of metallopeptidases. |
|
| DC20165 |
1,2,3,4,5,6-Hexabromocyclohexane;NSC7908 |
1,2,3,4,5,6-Hexabromocyclohexane is a potent inhibitor of JAK2 tyrosine kinase autophosphorylation with IC50 value to be estimated in low micromolar range. |
|
| DC12179 |
1,2-Dipalmitoyl-sn-glycerol 3-phosphate |
1,2-Dipalmitoyl-sn-glycerol 3-phosphate is a phosphatidic acid. |
|
| DC12239 |
1,3-Diaminopropane |
1,3-Diaminopropane, a three carbon diamine, is an ornithine decarboxylase inhibitor. |
|
| DC20292 |
103D5R |
103D5R is a small-molecule inhibitor of HIF-1α that displays an EC50 of 35 uM against hypoxia-induced alkaline phosphatase enzymatic reporter activity. |
|
| DC20094 |
10-Hydroxydecanoic acid (NSC 15139)
Featured
|
10-Hydroxydecanoic acid (NSC 15139) is a saturated fatty acid of 10-hydroxy-trans-2-decenoic acid from royal jelly, with anti-inflammatory activity. |
|
| DC20597 |
10-NCP |
10-NCP (10-DEBC) is a potent neuronal autophagy inducer and increases TDP43 clearance, a reversible and specific inhibitor of Akt activity in vitro (complete inhibition at < 5 uM). |
|
| DC9482 |
17-AAG
Featured
|
17-AAG (17-N-Allylamino-17-demethoxygeldanamycin), also known by its NSC number 330507 and CP number 127374, is a well-studied inhibitor of Heat Shock Protein 90 (HSP90). HSP90 is a molecular chaperone that plays a critical role in the stabilization and activation of a wide range of client proteins, many of which are involved in oncogenic processes. By inhibiting HSP90, 17-AAG disrupts the function of these client proteins, leading to the degradation of oncogenic proteins and ultimately inhibiting cancer cell growth and survival. |
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