| DC20214 |
3-Methoxyphenylacetic acid;m-Methoxyphenylacetic acid, P-Methoxyphenylacetic acid, Anisylacetic acid, m-OMePAA |
3-Methoxyphenylacetic acid is a monocarboxylic acid. |
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| DC12214 |
3-Methyl-2-oxovaleric acid |
3-Methyl-2-oxovaleric acid is a neurotoxin, an acidogen, and a metabotoxin, and also an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. |
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| DC22400 |
4-BBPB maleate |
4-BBPB maleate is a highly potent agonist of σ1 receptor with Ki of 0.8 nM. |
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| DC20186 |
4-Butylresorcinol
Featured
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4-Butylresorcinol is a potent inhibitor of tyrosinase and is used in cosmetics as a depigmenting agent. |
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| DC10644 |
α-CHCA |
4-Chloro-α-cyanocinnamic acid (α-CHCA) is a classic monocarboxylate transporters (MCT) inhibitor. α-cyano-4-hydroxycinnamate (CHC) has a 10-fold selectivity for MCT1 compared to other MCTs. |
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| DC21978 |
4-CPPC
Featured
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4-CPPC is the first reversible and selective inhibitor of pro-inflammatory protein macrophage migration inhibitory factor-2 (MIF-2) with Ki of 33 uM, 13-fold selectivity for human MIF-2 versus human MIF-1. |
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| DC10415 |
4E2RCat
Featured
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4E2RCat is an inhibitor of eIF4E-eIF4G interaction with an IC50 of 13.5 μM. |
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| DC20167 |
4-Hydroxyquinazoline;Quinazolin-4-ol, 4-Quinazolinol |
4-Hydroxyquinazoline is a PARP inhibitor with a high potency for PARP-1 and no effects on enzymes other than PARP. |
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| DC12067 |
4'-Methylchrysoeriol |
4'-Methylchrysoeriol is a potent inhibitor of Cytochrome P450 enzymes, with an IC50 of 19 nM for human P450 1B1-dependent EROD. |
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| DC8423 |
4SC-202 free base |
4SC-202 is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. Also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). Phase 1. |
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| DC9997 |
5,6-Dihydro-5-azacytidine |
5,6-Dihydro-5-azacytidine|cas 62488-57-7 |
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| DC20202 |
5-Bromoindole |
5-bromoindole is an important pharmaceutical chemical intermediate and a potential inhibitor of glycogen synthase kinase 3 (GSK-3). |
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| DC20168 |
5'-Cytidylic acid; Cytidine monophosphate, Cytidine 5'-phosphate |
5'-Cytidylic acid is a nucleotide that is used as a monomer in RNA. |
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| DC12703 |
5-Formyl-2-pyrimidinecarbonitrile
Featured
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5-Formyl-2-pyrimidinecarbonitrile is a chemical intermidate.. |
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| DC12335 |
5'-GTP trisodium salt hydrate (Guanosine 5'-triphosphate trisodium salt hydrate) |
5'-GTP trisodium salt hydrate is an activator of the signal transducing G proteins and also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA. |
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| DC5179 |
5-IODOTUBERCIDIN
Featured
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5-Iodotubercidin (Itu) has been shown to inhibit mitogen-activated protein kinase (ERK2) (Ki = 525 nM), adenosine kinase (ADK) (Ki = 30 nM), casein kinases 1 & 2 (CSNK1A1 & CSNK2A1), protein kinase A (PKA) and insulin receptor kinase (IC50 ranging from 0. |
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| DC20150 |
5-Methoxyflavone |
5-Methoxyflavone, belonged to Flavonoid family, is a DNA polymerase-beta inhibitor and neuroprotective agent against beta-amyloid toxicity. possess central nervous system (CNS) depressant effect mediated through the ionotropic GABAA receptors. |
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| DC10990 |
5MPN |
5MPN a first-in-class, selective, competitive, orally available inhibitor of PFKFB4 with Ki of 8.6 uM, does not inhibit PFK-1 or PFKFB3. |
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| DC23335 |
5-NIdR |
5-NIdR (5-nitro-indolyl-2'-deoxynucleoside) is a non-natural nucleotide produces cytostatic and cytotoxic effects against human leukemia cells by altering cell-cycle progression. |
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| DC23334 |
5-NITP |
5-NITP (5-nitro-indolyl-2'-deoxyribose triphosphate) is a non-natural nucleotide that inhibits ribonucleotide reductase (hRR) with IC50 of 170 uM, demonstrates anti-cancer effects against leukemia cells by altering cell-cycle progression.. |
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| DC9444 |
5-R-Rivaroxaban |
5-R-Rivaroxaban is (R) enantiomer of Rivaroxaban. |
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| DC20195 |
6-(Dimethylamino)purine；N,N-Dimethyladenine |
6-Dimethylaminopurine is a serine threonine protein kinase inhibitor. It inhibits the germinal vesicle breakdown and the meiotic maturation of oocytes. |
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| DC23336 |
6-Ethylthioinosine |
6-Ethylthioinosine (6-ETI. |
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| DC20604 |
6-FABA |
6-FABA (6-Fluoroanthranilic Acid) is a small-molecule inhibitor of MTB tryptophan synthesis that converts Mtb into a tryptophan auxotroph and restores the efficacy of a failed host defense. |
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| DC9376 |
6-FITC |
6-Fluorescein isothiocyanate(6-FITC) is a derivative of fluorescein used in wide-ranging applications including flow cytometry. |
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| DC12326 |
6-Hydroxybentazon (6-Hydroxybentazone) |
6-Hydroxybentazon is a phase I metabolite of bentazone, and bentazone is a chemical for use in herbicides. |
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| DC20297 |
6-Hydroxy-DL-DOPA
Featured
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6-Hydroxy-DL-DOPA is a small-molecule that disrupts with RAD52 oligomerization, inhibits ssDNA binding by RAD52 with IC50 of 1.1 uM and by RAD52 (1 209) with IC50 of 1.6 uM. |
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| DC8864 |
6-Mercaptopurine (6-MP) Monohydrate |
6-Mercaptopurine Monohydrate is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA. |
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| DC12540 |
6-MOMIPP |
6-MOMIPP is a novel microtubule disruptor that targets the colchicine binding site on β-tubulin, induces mitotic arrest, caspase activation and loss of cell viability of U251 glioblastoma in vitro. |
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| DC10215 |
7,8-Dihydroxyflavone |
7,8-Dihydroxyflavone acts as a potent and selective small-molecule agonist of the TrkB receptor (Kd ≈ 320 nM), the main signaling receptor of brain-derived neurotrophic factor (BDNF). |
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