| DC20294 |
1835F03 |
1835F03 is a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus, inhibits the growth of a panel of S aureus strains (MIC=1-3 ug/mL), including clinical MRSA isolates.. |
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| DC5144 |
1-Azakenpaullone
Featured
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1-Azakenpaullone is a potent and ATP-competitive GSK-3β (glycogen synthase kinase-3β) inhibitor (IC₅₀ = 18 nM). |
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| DC23261 |
1E7-03 |
1E7-03 is a small molecule targeting the RVxF interacting site on PP1, inhibits HIV-1, Ebolavirus (EBOV), and Venezuelan equine encephalitis virus (VEEV, EC50=0.6 uM). |
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| DC8649 |
1-Methyl-7-nitroisatoic anhydride
Featured
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1-methyl-7-nitroisatoic anhydride is a reagent that detects local nucleotide flexibility, for probing 2'-hydroxyl reactivity. |
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| DC10184 |
2-(Pyridyldithio)ethylamine hydrochloride |
2-(Pyridyldithio)ethylamine hydrochloride is a novel disulfideintercalating cross-linking reagent. |
ethylamine hydrochloride.gif)
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| DC20140 |
Cyclouridine
Featured
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2,2'-Cyclouridine is a research tool for antiviral and anticancer studies. |
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| DC7972 |
2,4-Pyrimidinediamine with linker
Featured
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2,4-Pyrimidinediamine with linker is a patent compound in WO2013055780A1, Page 71; multikinase inhibitor and has a -NH2 terminal linker for further synthesis. |
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| DC23878 |
20(S)-Hydroxycholesterol |
20(S)-Hydroxycholesterol is an allosteric activator of the Hedgehog signaling pathway Smoothened (Smo) oncoprotein, binds at a site distinct from the canonical cyclopamine binding site. |
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| DC9655 |
20-O-Acetylingenol-3-angelate
Featured
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20-O-Acetylingenol-3-angelate is a diterpene ester that has been found in E. peplus and a derivative of ingenol-3-angelate |
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| DC23871 |
22-Azacholesterol |
22-Azacholesterol is the first small molecule inhibitor that inhibits Hedgehog (Hh) signaling by binding the oxysterol-binding site of Smo, inhibits Sonic Hedgehog (Shh) signaling with IC50 of 3 uM in NIH-3T3 cells.. |
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| DC12231 |
25-Hydroxycholesterol
Featured
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25-Hydroxycholesterol is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. 25-hydroxycholesterol is a potent (EC50≈65 nM) and selective suppressor of IgA production by B cells. |
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| DC20210 |
2-Aminoethanethiol;cysteamine, β-Mercaptoethylamine, 2-Mercaptoethylamine, Decarboxycysteine, Thioethanolamine, Mercaptamine |
2-Aminoethanethiol (cysteamine) is a radiation-protective agent that oxidizes in air to form cystamine. |
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| DC22088 |
2BAct
Featured
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2BAct (eIF2B activator 2BAct) is a novel, highly selective, CNS-permeable small molecule eIF2B activator with EC50 of 33 nM in cell-based reporter assays. |
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| DC20184 |
2-cyano-Pyrimidine |
2-cyano-Pyrimidine is a cathepsin K inhibitor with an IC50 of 170 nM. |
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| DC20158 |
2'-Deoxyadenosine monohydrate
Featured
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2'-Deoxyadenosine monohydrate is a deoxyribonucleoside. A building block in the chemical synthesis. |
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| DC20144 |
2-Furoic acid
Featured
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2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation. 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats. |
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| DC20137 |
2'-Hydroxy-4'-methylacetophenone
Featured
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2'-Hydroxy-4'-methylacetophenone, a phenolic compound isolated from Angelicae koreana roots possesses acaricidal property. It could be used in the preparation of 4’-methyl-2’-[(p-tolylsulfonyl) oxy] acetophenone. |
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| DC12356 |
2-NBDG
Featured
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2-NBDG is a fluorescent indicator for direct glucose uptake measurement and also is an indicator of cell viability. |
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| DC12293 |
2''-O-Rhamnosylicariside II |
2''-O-Rhamnosylicariside II is a flavonoid glycoside compound and might be beneficial for improving postmenopausal osteoporosis. |
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| DC8572 |
2-Phenyl-2-(1-piperidinyl)propane |
2-Phenyl-2-(1-piperidinyl)propane is an analog of phencyclidine that acts as a mechanism-based inactivator of human cytochrome P450 (CYP) 2B6 (Ki = 5.6 µM; IC50 = 5.1 µM). |
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| DC20134 |
2-Phenylethanol
Featured
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2-Phenylethanol (Phenethyl alcohol), extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid that is slightly soluble in water. It has a pleasant floral odor and also an autoantibiotic produced by |
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| DC8567 |
3-(4-Pyridyl)
Featured
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3-(4-Pyridyl)indole is a ROCK-I inhibitor (IC50 = 25 µM) that promotes cell spreading, inhibits membrane blebbing, and induces dissolution of actin stress fibers in a wound healing assay |
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| DC9892 |
3,3'-Diindolylmethane
Featured
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3,3'-Diindolylmethane(DIM) is a major digestive product of indole-3-carbinol, a potential anticancer component of cruciferous vegetables. |
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| DC20128 |
3,4-Dimethoxycinnamic acid (O-Methylferulic acid)
Featured
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3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer extracted and purified from Securidaca inappendiculata Hassk. 3,4-Dimethoxycinnamic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway. Anti-apoptotic effe |
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| DC12240 |
3b-Hydroxy-5-cholenoic acid |
3b-Hydroxy-5-cholenoic acid is a monohydroxy bile acid of endogenous origin and could be found in children with the syndrome of hepatic ductular hypoplasia. |
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| DC11060 |
3-Bromo-7-Nitroindazole |
3-Bromo-7-Nitroindazole is a more potent inhibitor of nNOS than 7-nitroindazole in vitro, is also potent against iNOS, inhibits rat nNOS, bovine eNOS, and rat iNOS with IC50 of 0.17, 0.86, and 0.29 uM.. |
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| DC20296 |
3-Cyanochromone |
3-Cyanochromone is a potent gram-negative bacteria WcbL protein inhibitor with IC50 of 28 uM in a competitive enzyme-inhibition model, shows inhibition constants Ki of 10 uM.. |
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| DC12357 |
3-Deazaadenosine hydrochloride |
3-Deazaadenosine (hydrochloride) is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 µM; 3-Deazaadenosine has anti-inflammatory, anti-proliferative and anti-HIV activity. |
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| DC5190 |
3-Deazaneplanocin A (DZNep）
Featured
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3-deazaneplanocin A (DZNeP), an analog of adenosine, is a competitive inhibitor of S-adenosylhomocysteine hydrolase with Ki of 50 pM. |
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| DC22994 |
3-Ethoxy-5,6-dibromosalicylaldehyde |
3-Ethoxy-5,6-dibromosalicylaldehyde is a potent and selective inhibitor of IRE1 endoribonuclease with IC50 of 0.12 uM. |
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