Cat. No. | Product name | CAS No. |
DC11346 |
Salbutamol (hydrochloride)
Featured
Salbutamol is an agonist of the β2-adrenergic receptor (β2-AR; Kd = 759 nM in a radioligand binding assay using CHO cells expressing the human receptor). |
50293-90-8 |
DC7275 |
Salidroside
Featured
Salidroside, a phenylpropanoid glycoside isolated from Rhodiola rosea, has been reported to have a broad spectrum of pharmacological properties. |
10338-51-9 |
DC11014 |
SALL4 peptide FFW
Featured
SALL4 peptide FFW (RRKFAKFQWI, FFW peptide) is a potent therapeutic SALL4 peptide antagonist of SALL4-NURD (nucleosome remodeling deacetylase) interaction with target affinity of 23 nM. |
|
DC5988 |
Salvianolic acid A
Salvianolic acid A acts as scavengers of reactive oxygen species, reduces the adherence of leukocytes to endothelial cells, inhibits matrix metalloproteinases and inflammation. |
96574-01-5 |
DC21143 |
Samatasvir
Samatasvir (IDX719) is a highly potent, selective inhibitor of HCV NS5A that effectively inhibits HCV genotype 1-5 replicons with EC50 of 2-24 pM. |
1312547-19-5 |
DC23264 |
SAMT-247
SAMT-247 potent HIV-1 nucleocapsid protein NCp7 inhibitor with EC50 of 0.6 uM with low cellular toxicity (TC50>100 uM) in cultured and primary cells. |
850715-59-2 |
DC20543 |
San78-130
San78-130 is a potent, selective activin receptor-like Kinase 1 (ALK1) inhibitor with IC50 of 62 nM, with greater selectivity compared with L-783277. |
66018-45-9 |
DC22222 |
SAN9812
SAN9812 (Carnostatine) is a potent, highly selective, competitive inhibitor of Carnosinase 1 (CN1) activity with Ki of 11 nM. |
|
DC20182 |
Sapropterin Dihydrochloride;Tetrahydrobiopterin Dihydrochloride, R-THBP Dihydrochloride
Sapropterin Dihydrochloride, a synthetic preparation of the dihydrochloride salt of naturally occurring tetrahydrobiopterin (BH4), is a phenylalanine hydroxylase activator. |
69056-38-8 |
DC10925 |
SAR-100842
SAR-100842 (SAR100842) is a potent, selective, orally available antagonist of the Lysophosphatidic Acid 1 Receptor (LPA1 receptor) with IC50 of 31 nM in β-arrestin assays. |
1195941-38-8 |
DC22414 |
SAR-216471 hydrochloride
SAR-216471 is a potent, highly selective, intravenous and oral, reversible P2Y12 receptor antagonist with binding IC50 of 17 nM. |
1279829-64-9 |
DC12589 |
SAR260301
SAR260301 (SAR-260301, SAR 260301) is a potent, selective, ATP-competitive PI3Kβ inhibitor with IC50 of 52 nM in TR-FRET assays, with littile to no actiivty against PI3Kα/γ/δ (IC50=1,869/>10,000/403 nM, respectively). |
1260612-13-2 |
DC22521 |
SAR405
Featured
SAR405 is a highly potent and selective PI3K class III isoform Vps34 inhibitor with IC50 of 1.2 nM, inhibits the formation of autophagosomes in GFP-LC3 cells with IC50 of 4 nM. |
1523406-39-4 |
DC8104 |
SAR407899 HCl
SAR407899 Hcl is a potent, ATP-competitive ROCK inhibitor woth Ki value of 36 nM/41 nM for human ROCK/Rat ROCK respectively. |
923262-96-8 |
DC21605 |
SAS-0132
SAS-0132 (SAS132) is a novel potent, subtype-selective, brain penetrant sigma 2 receptor/PGRMC1 ligand with Ki of 90 nM, 9-fold selectivity over sigma 1 receptors. |
2095551-89-4 |
DC24018 |
Satraplatin
Satraplatin (BMS-182751, BMY-45594, JM-216) is a platinum-based antineoplastic agent that binds to guanine residues in DNA, inhibits DNA replication and transcription, leads to subsequent apoptosis. |
129580-63-8 |
DC20051 |
Sauristolactam (Saurolactam)
Sauristolactam, a natural aristolactam isolated from aerial portions of Saururus chinensis, has significant neuroprotective activity against glutamate-induced toxicity in primary cultured rat cortical cells. Sauristolactam also inhibits the receptor activ |
128533-02-8 |
DC12330 |
SB 204990
SB 204990 is a potent and specific inhibitor of ATP citrate lyase (ACLY) enzyme. |
154566-12-8 |
DC21608 |
SB 206553
SB 206553 is a potent and selective 5-HT2B/5-HT2C receptor antagonist with pA2 of 8.89 for rat 5-HT2B, pKi of 7.92 for human 5-HT2C, displays >80-fold selectivity over other 5-HT receptor subtypes. |
1197334-04-5 |
DC7245 |
SB 222200
SB 222200 is a selective, reversible and competitive antagonist of human NK-3 receptor(Ki=4.4 nM) that effectively crosses the blood-brain barrier. |
174635-69-9 |
DC8878 |
SB 242084
SB 242084 is a potent and selective antagonist of 5-HT2C receptor. |
181632-25-7 |
DC21620 |
SB 737050A
SB 737050A is a potent, selective 5-HT6 receptor antagonist to prevent relapse intio addiction.. |
583045-76-5 |