| DC23523 |
Elubrixin tosylate |
Elubrixin (SB-656933) is a potent, selective, competitive and reversible CXCR2 antagonist. |
|
| DC21618 |
Elubrixin |
Elubrixin (SB-656933, GSK-656933) is a potent, selective, competitive and reversible CXCR2 antagonist. |
|
| DC8625 |
Eluxadoline Dihydrochloride
Featured
|
Eluxadoline Dihydrochloride is an orally active mixed μ opioid receptor (μOR) agonist δ opioid receptor (δOR) antagonist. |
|
| DC8626 |
Eluxadoline
Featured
|
Eluxadoline is an orally active mixed μ opioid receptor (μOR) agonist δ opioid receptor (δOR) antagonist. |
|
| DC4235 |
Elvitegravir（GS9137）
Featured
|
Elvitegravir (EVG) is a drug used for the treatment of HIV infection. It acts as an integrase inhibitor. |
|
| DC21465 |
EMA300 |
EMA300 (PD1 21981) is a potent, selective small molecule antagonist of angiotensin II type 2 receptor (AT2R) with >1,000-fold selectivity over AT1 receptor, produces analgesia in rodent model of neuropathic pain.. |
|
| DC10870 |
EMA400
Featured
|
EMA400 is a potent and highly selective AT2R antagonist. |
|
| DC10869 |
Olodanrigan(EMA401)
Featured
|
EMA401(Olodanrigan) is a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons. |
|
| DC8706 |
Emamectin Benzoate |
Emamectin Benzoate works as a chloride channel activator by binding gamma aminobutyric acid (GABA) receptor and glutamate-gated chloride channels disrupting nerve signals within arthropods. |
|
| DC7731 |
Emapunil(AC-5216)
Featured
|
Emapunil(AC-5216;XBD-173) is a translocator protein |
|
| DC11028 |
EMD-281014 hydrochloride |
EMD-281014 hydrochloride is a potent, highly selective 5-HT2A antagonist with Ki of 0.87 nM, displays little to no affinity for 5-HT2C receptors (Ki=557 nM), human D2 receptors and IKr channels. |
|
| DC11027 |
EMD-281014 |
EMD-281014 is a potent, highly selective 5-HT2A antagonist with Ki of 0.87 nM, displays little to no affinity for 5-HT2C receptors (Ki=557 nM), human D2 receptors and IKr channels. |
|
| DC7117 |
EMD534085 |
EMD534085 is a kinesin inhibitor currently in clinical development. |
|
| DC9620 |
EMD638683
Featured
|
EMD638683 is a potent SGK1 inhibitor with an IC50 of 3 uM. |
|
| DC8885 |
EMICORON
Featured
|
EMICORON is a novel G-quadruplex (G4) ligand showing high selectivity for G4 structures over the duplex DNA, causing telomere damage and inhibition of cell proliferation in transformed and tumor cells. |
|
| DC9771 |
ACU4429,ACU 4429,ACU-4429
Featured
|
Emixustat hydrochloride strongly inhibits 11-cis-retinol production with IC50 values of 232 ± 3 nM. |
|
| DC10314 |
Emixustat |
Emixustat, a novel visual cycle modulator, is an inhibitor of the visual cycle isomerase with an IC50 value of 4.4 nM in vitro. |
|
| DC22785 |
EML-405 |
EML-405 (EML405) is a small-molecule inhibitor of Spindlin1 (SPIN1) with Kd of 14 uM. |
|
| DC10301 |
Emodepside
Featured
|
Emodepside (PF 1022-221) is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity. |
|
| DC5018 |
Empagliflozin (BI-10773)
Featured
|
Empagliflozin is a potent, selective sodium glucose co-transporter-2 inhibitor that is in development for the treatment of type 2 diabetes. Empagliflozin is an inhibitor of the sodium glucose co-transporter-2 (SGLT-2), which is found almost exclusively in |
|
| DC23171 |
Empesertib(BAY 1161909)
Featured
|
Empesertib (BAY-1161909, BAY1161909) is a potent, selective Monopolar spindle 1 (Mps1/TTK) inhibitor with IC50 of 0.34 nM. |
|
| DC9762 |
Emricasan
Featured
|
Emricasan (IDN-6556, PF-03491390) is a potent irreversible pan-caspase inhibitor. |
|
| DC12273 |
EMT inhibitor-1 |
EMT inhibitor-1 is an inhibitor of of Hippo, TGF-β, and Wnt signaling pathways with antitumor activities. |
|
| DC5902 |
Emtricitabine
Featured
|
Emtricitabine is a nucleoside analogue which inhibits the reverse nucleoside transcriptase enzyme. Structurally this antiviral agent is similar to Lamivudine. This agent is effective at targeting HIV and HBV viruses since these viruses replicate in a reve |
|
| DC23108 |
EN460
Featured
|
EN460 is a specific mall molecule inhibitor of endoplasmic reticulum oxidation 1 (ERO1), interacts selectively with the reduced, active form of ERO1α and prevents its reoxidation (IC50=1.9 uM). |
|
| DC24204 |
EN6
Featured
|
EN6 is a small-molecule in vivo activator of autophagy that covalently targets cysteine 277 in the ATP6V1A subunit of the lysosomal v-ATPase, which activates mTORC1 via the Rag guanosine triphosphatases. |
|
| DC20892 |
Enadoline |
Enadoline (CI 977. |
|
| DCAPI1334 |
Enalapril maleate (Vasotec) |
Enalapril maleate (Vasotec) |
|
| DC8177 |
Enclomiphene citrate
Featured
|
Enclomiphene is a non-steroidal estrogen receptor antagonist that promotes gonadotropin-dependent testosterone secretion by the testes. |
|
| DC9959 |
Endoxifen (E-isomer)
Featured
|
Endoxifen (E-isomer hydrochloride) is a tamoxifen metabolite and potent Selective Estrogen Response Modifier (SERM). |
|
