DC9247 |
AP-III-a4 hydrochloride
Featured
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ENOblock Hcl(AP-III-a4 Hcl) is a novel small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 uM); inhibit cancer cell metastasis in vivo. |
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DC7119 |
ENO block(AP-III-a4)
Featured
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ENOblock(AP-III-a4) is a novel small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 uM); inhibit cancer cell metastasis in vivo. |
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DC8778 |
Enocitabine |
Enocitabine is an anti-tumor agent and an antineoplastic. A derivative of Cytarabine. |
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DC20018 |
Enocyanin
Featured
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Enocyanin is an anthocyanin extracted from grapes. Enocyanin shows inhibitory effect on the leucine aminopeptidase, acid phosphatase, γ-glutamyl transpeptidase and esterase activity. |
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DC10547 |
Ensartinib
Featured
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Ensartinib is a potent inhibitor of ALK, which is used to treat non-small-cell lung cancer. |
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DC8321 |
Entacapone
Featured
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Entacapone is a specific, potent, peripherally acting catechol-O-methyltransferase (COMT) inhibitor with IC50 of 151 nM for PD treatment. |
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DC4208 |
Entecavir Monohydrate
Featured
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Entecavir hydrate belongs to the family of medicines called antivirals. |
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DC8881 |
Entecavir |
Entecavir is a deoxyguanosine nucleoside analogue with antiviral activity against the hepatitis B virus (HBV). |
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DC6909 |
Entinostat (MS-275)
Featured
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Entinostat (MS-275) strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM, compared with HDACs 4, 6, 8, and 10. Phase 1/2. |
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DC24202 |
Ent-kaurene
Featured
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Ent-kaurene is a tetracyclic diterpene consisting of ent-kaurane, where the 6-methyl group is replaced by methylene. It derives from a hydride of an ent-kaurane. |
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DC8300 |
Entrectinib (RXDX-101)
Featured
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Entrectinib (RXDX-101), a potent and selective small molecule inhibitor of TrkA/B/C, ROS1, and ALK kinases, has demonstrated early clinical activity when orally administered intermittently under fasting conditions. |
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DC21856 |
Enviroxime |
Enviroxime (Zinviroxime. |
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DC20848 |
Enzaplatovir |
Enzaplatovir (BTA-585, BTA-C585) is an orally bioavailable RSV fusion protein inhibitor for the treatment of respiratory syncytial virus infections.. |
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DC5057 |
Enzastaurin (LY317615)
Featured
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Enzastaurin (LY317615) is a potent PKCβ selective inhibitor with IC50 of 6 nM, 6- to 20-fold selectivity against PKCα, PKCγ and PKCε. Phase 3. |
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DC20950 |
EOAI3402143 |
EOAI3402143 (Deubiquitinase inhibitor G9, EOAI 3402143) is a novel covalent deubiquitinase Usp9x/Usp24 inhibitor with increased aqueous solubility and greater cellular Usp9x inhibitory activity than WP1130. |
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DC8389 |
Epacadostat (INCB024360)
Featured
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Epacadostat (INCB024360) is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM. Phase 2. |
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DCAPI1356 |
Epalrestat
Featured
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Epalrestat is an orally active aldose reductase inhibitor that acts on diabetic neuropathy. |
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DC21601 |
Epertinib |
Epertinib (S-222611) is a novel potent, orally active, reversible EGFR and HER2 inhibitor with IC50 of 1.48, 7.15 and 2.49 nM for EGFR, HER2 and HER4, respectively. |
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DC20374 |
EphB3-IN-1 |
EphB3-IN-1 is the first potent, selective inhibitor of EphB3 that exhibits inhibiting EphB3 autophosphorylation in cells with IC50 of 3 nM. |
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DC8856 |
EPI-001
Featured
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EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ∼6 μM and a selective PPAR-gamma modulator |
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DC11433 |
Vatiquinone |
EPI-743 (Vatiquinone,EPI-589) is an orally bioavailable para-benzoquinone for treatment of inherited mitochondrial diseases, an analogue of the antioxidant ubidecarenone. |
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DC8693 |
Epiandrosterone
Featured
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Epiandrosterone is a steroid hormone with weak androgenic activity. Epiandrosterone is naturally produced by the enzyme 5α-reductase from the adrenal hormone DHEA. |
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DC9363 |
Epibrassinolide |
Epibrassinolide (EBR; B1105; 24-Epibrassinolide) is a biologically active compound of the brassinosteroids, steroid-derived plant growth regulator family; was shown as a potential apoptotic inducer in various cancer cells without affecting the non-tumor c |
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DC23071 |
Epigoitrin
Featured
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Epigoitrin and fructopyrano-(1→4)-glucopyranose(FG) from the traditional Chinese medicine Isatidis radix, exhibit in vitro cooperation, they have in vitro anti-virus activity. |
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DC9467 |
Epinastine
Featured
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Epinastine(WAL801) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.
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DCAPI1014 |
Eplerenone
Featured
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Eplerenone, also known as Inspra and CGP-30083, is a selective aldosterone receptor antagonist used to treat hypertension and congestive heart failure. Eplerenone provides marked protection against vascular injury in the kidney and heart.
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DC23786 |
Epolactaene |
Epolactaene is a neuritogenic fungal isolate that arrests the cell cycle at the G0/G1 phase and induces the outgrowth of neurites in human neuroblastoma SH-SY5Y cells. |
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DC7120 |
Epothilone A |
Epothilone A is a Taxol-like microtubule-stabilizing agent that induces tubulin polymerization, leading to cell cycle arrest at the G2-M transition, cytotoxicity, and apoptosis. |
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DC4198 |
Epothilone B
Featured
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Epothilone B is a Taxol-like microtubule-stabilizing agent with EC0.01 of 1.8 μM. |
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DC7012 |
Epothilone D |
Epothilone D(Desoxyepothilone B; KOS 862) is a natural polyketide compound isolated from the myxobacterium Sorangium cellulosum. |
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