| DC8403 |
Endoxifen (Z-isomer hydrochloride)
Featured
|
Endoxifen HCl, the active metabolite of Tamoxifen, ia a potent and selective estrogen receptor antagonist. Phase 2. |
|
| DC8265 |
Endoxifen
Featured
|
Endoxifen is a Estrogen receptor α (ERα) ligand; potent antiestrogen,an active metabolite of the cancer drug tamoxifen. |
|
| DC7589 |
Eniporide(EMD96785)
Featured
|
Eniporide is a The Na(+)/H(+) exchange inhibitor. |
|
| DC20993 |
ENMD-1068
Featured
|
ENMD-1068 is a novel selective PAR2 antagonist without inhibitory activity against thrombin-mediated PAR3 and PAR4 signaling. |
|
| DC7118 |
ENMD-2076
Featured
|
ENMD-2076 has selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold selective for Aurora A than over Aurora B and less potent to VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFRα. |
|
| DC9247 |
AP-III-a4 hydrochloride
Featured
|
ENOblock Hcl(AP-III-a4 Hcl) is a novel small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 uM); inhibit cancer cell metastasis in vivo. |
|
| DC7119 |
ENO block(AP-III-a4)
Featured
|
ENOblock(AP-III-a4) is a novel small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 uM); inhibit cancer cell metastasis in vivo. |
|
| DC8778 |
Enocitabine |
Enocitabine is an anti-tumor agent and an antineoplastic. A derivative of Cytarabine. |
|
| DC20018 |
Enocyanin
Featured
|
Enocyanin is an anthocyanin extracted from grapes. Enocyanin shows inhibitory effect on the leucine aminopeptidase, acid phosphatase, γ-glutamyl transpeptidase and esterase activity. |
|
| DC10547 |
Ensartinib
Featured
|
Ensartinib is a potent inhibitor of ALK, which is used to treat non-small-cell lung cancer. |
|
| DC8321 |
Entacapone
Featured
|
Entacapone is a specific, potent, peripherally acting catechol-O-methyltransferase (COMT) inhibitor with IC50 of 151 nM for PD treatment. |
|
| DC4208 |
Entecavir Monohydrate
Featured
|
Entecavir hydrate belongs to the family of medicines called antivirals. |
|
| DC8881 |
Entecavir |
Entecavir is a deoxyguanosine nucleoside analogue with antiviral activity against the hepatitis B virus (HBV). |
|
| DC6909 |
Entinostat (MS-275)
Featured
|
Entinostat (MS-275) strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM, compared with HDACs 4, 6, 8, and 10. Phase 1/2. |
|
| DC24202 |
Ent-kaurene
Featured
|
Ent-kaurene is a tetracyclic diterpene consisting of ent-kaurane, where the 6-methyl group is replaced by methylene. It derives from a hydride of an ent-kaurane. |
|
| DC8300 |
Entrectinib (RXDX-101)
Featured
|
Entrectinib (RXDX-101), a potent and selective small molecule inhibitor of TrkA/B/C, ROS1, and ALK kinases, has demonstrated early clinical activity when orally administered intermittently under fasting conditions. |
|
| DC21856 |
Enviroxime |
Enviroxime (Zinviroxime. |
|
| DC20848 |
Enzaplatovir |
Enzaplatovir (BTA-585, BTA-C585) is an orally bioavailable RSV fusion protein inhibitor for the treatment of respiratory syncytial virus infections.. |
|
| DC5057 |
Enzastaurin (LY317615)
Featured
|
Enzastaurin (LY317615) is a potent PKCβ selective inhibitor with IC50 of 6 nM, 6- to 20-fold selectivity against PKCα, PKCγ and PKCε. Phase 3. |
|
| DC20950 |
EOAI3402143 |
EOAI3402143 (Deubiquitinase inhibitor G9, EOAI 3402143) is a novel covalent deubiquitinase Usp9x/Usp24 inhibitor with increased aqueous solubility and greater cellular Usp9x inhibitory activity than WP1130. |
|
| DC8389 |
Epacadostat (INCB024360)
Featured
|
Epacadostat (INCB024360) is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM. Phase 2. |
|
| DCAPI1356 |
Epalrestat
Featured
|
Epalrestat is an orally active aldose reductase inhibitor that acts on diabetic neuropathy. |
|
| DC21601 |
Epertinib |
Epertinib (S-222611) is a novel potent, orally active, reversible EGFR and HER2 inhibitor with IC50 of 1.48, 7.15 and 2.49 nM for EGFR, HER2 and HER4, respectively. |
|
| DC20374 |
EphB3-IN-1 |
EphB3-IN-1 is the first potent, selective inhibitor of EphB3 that exhibits inhibiting EphB3 autophosphorylation in cells with IC50 of 3 nM. |
|
| DC8856 |
EPI-001
Featured
|
EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ∼6 μM and a selective PPAR-gamma modulator |
|
| DC11433 |
Vatiquinone |
EPI-743 (Vatiquinone,EPI-589) is an orally bioavailable para-benzoquinone for treatment of inherited mitochondrial diseases, an analogue of the antioxidant ubidecarenone. |
|
| DC8693 |
Epiandrosterone
Featured
|
Epiandrosterone is a steroid hormone with weak androgenic activity. Epiandrosterone is naturally produced by the enzyme 5α-reductase from the adrenal hormone DHEA. |
|
| DC9363 |
Epibrassinolide |
Epibrassinolide (EBR; B1105; 24-Epibrassinolide) is a biologically active compound of the brassinosteroids, steroid-derived plant growth regulator family; was shown as a potential apoptotic inducer in various cancer cells without affecting the non-tumor c |
|
| DC23071 |
Epigoitrin
Featured
|
Epigoitrin and fructopyrano-(1→4)-glucopyranose(FG) from the traditional Chinese medicine Isatidis radix, exhibit in vitro cooperation, they have in vitro anti-virus activity. |
|
| DC9467 |
Epinastine
Featured
|
Epinastine(WAL801) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.
|
|
