| DC10225 |
Lidocaine hydrochloride |
Lidocaine hydrochloride is a local anesthetic and cardiac depressant used as an antiarrhythmia agent. |
|
| DC8986 |
Lidocaine |
Lidocaine, an amide local anesthetic, has anti-inflammatory properties in vitro and in vivo, possibly due to an attenuation of pro-inflammatory cytokines, intracellular adhesion molecule-1 (ICAM-1), and reduction of neutrophils influx. |
|
| DC20198 |
Lifirafenib;BGB-283;Beigene-283 |
Lifirafenib (BGB-283) potently inhibits RAF family kinases and EGFR activities in biochemical assays with IC50 values of 23, 29 and 495 nM for the recombinant BRAFV600E kinase domain, EGFR and EGFR T790M/L858R mutant. |
|
| DC10099 |
BGB283 |
Lifirafenib（BGB-283） is a Novel potent and selective RAF Kinase and EGFR inhibitor. |
|
| DC26014 |
Lifitegrast sodium
Featured
|
Lifitegrast sodium, also known as SAR-1118, is an LFA-1 antagonist intended for the treatment of vascular complications of the eye. |
|
| DC23065 |
Ligustilide
Featured
|
Ligustilide possesses neuroprotective, vasorelaxation, antinociceptive and anti-inflammatory activities, it blocked the activation of MAPKs/IKK and the downstream transcription factors AP-1 and NF-κB. |
|
| DC21914 |
LIMK1 and 2 dual inhibitor |
LIMK1 and 2 dual inhibitor is a potent, selective LIMK1/2 inhibitor with IC50 of <10 nM for both, 15-fold selectivity over B-Raf (IC50=10-100 nM). |
|
| DC21915 |
LIN28 inhibitor LI71
Featured
|
LIN28 inhibitor LI71 is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 7 uM, binds the cold shock domain to suppress LIN28's activity against let-7 in leukemia cells and embryonic stem cells. . |
|
| DC20436 |
Lin28-IN-1 |
Lin28-IN-1 is a small-molecule inhibitor of the Lin28/let-7 interaction with IC50 of 4.03 uM. |
|
| DC1105 |
Linagliptin (BI-1356)
Featured
|
Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM. |
|
| DCAPI1373 |
Lincomycin HCl (Lincocin) |
Lincomycin HCl (Lincocin) |
|
| DC23026 |
Linderane
Featured
|
Linderane is a mechanism-based inactivator of CYP2C9. |
|
| DC6905 |
Linezolid (PNU-100766)
Featured
|
Linezolid (Zyvox) is a synthetic antibiotic used for the treatment of serious infections. |
|
| DC10820 |
Roquinimex(Linomide)
Featured
|
Linomide is an Immunomodulator; anti-angiogenic. |
|
| DC20982 |
Linopirdine dihydrochloride |
Linopirdine (DUP-996) is a potent Kv7 (KCNQ) voltage-gated potassium channels blcoker. |
|
| DC20983 |
Linopirdine |
Linopirdine (DUP-996. |
|
| DC9188 |
Liothyronine sodium
Featured
|
Liothyronine sodium (T3 Sodium sal) is the most potent form of thyroid hormone used to treat hypothyroidism and myxedema coma. |
|
| DC11011 |
Lipofermata
Featured
|
Lipofermata (CB16.2 aka) is a specific fatty acid transport (FATP) inhibitor, blocks human FATP2-mediated fatty acid uptake (IC50=4.84 uM in Caco-2 cells) without impacting other cellular functions. |
|
| DC26056 |
Liproxstatin-1 analog |
Liproxstatin-1 analog is an analog of the ferroptosis inhibitor liproxstatin-1 |
|
| DC7920 |
Liproxstatin-1
Featured
|
Liproxstatin-1 is able to suppress ferroptosis in cells, in Gpx4(-/-) mice, and in a pre-clinical model of ischaemia/reperfusion-induced hepatic damage. |
|
| DC8927 |
Liraglutide
Featured
|
Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus. |
|
| DC23664 |
Lirimilast |
Lirimilast (BAY 19-8004. |
|
| DC9123 |
Lisinopril Dihydrate |
Lisinopril Dihydrate is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks. |
|
| DC12433 |
LIT-001
Featured
|
LIT-001 (LIT001) is the first nonpeptide Oxytocin receptor (OT-R) agonist with EC50 of 55 nM, Emax=96%. |
|
| DC12434 |
LIT-001 trifluoroacetate
Featured
|
LIT-001 trifluoroacetate (LIT001) is the first nonpeptide Oxytocin receptor (OT-R) agonist with EC50 of 55 nM, Emax=96%. |
|
| DC8689 |
Litronesib |
Litronesib is a selective, allosteric inhibitor of Eg5, which may result in mitotic disruption, apoptosis and consequently cell death in tumor cells that are actively dividing. |
|
| DC4138 |
Lixivaptan (VPA-985)
Featured
|
Lixivaptan is a highly potent, non-peptide, oral capsule that works by reducing the action of a hormone (vasopressin) that blocks fluid excretion. |
|
| DC21233 |
LJ 001
Featured
|
LJ 001 ((LJ-001, LJ001) is a broad-spectrum antiviral agent targeting entry of enveloped viruses, including influenza A, filoviruses, poxviruses, arenaviruses, bunyaviruses, paramyxoviruses, flaviviruses, and HIV-1; specifically intercalates into viral membranes, irreversibly inactivates virions while leaving functionally intact envelope proteins, and inhibits viral entry at a step after virus binding but before virus-cell fusion; specifically inhibits virus-cell but not cell-cell fusion |
|
| DC8811 |
LJH-685
Featured
|
LJH685 is a selective and potent RSK inhibitor. |
|
| DC8812 |
LJI-308
Featured
|
LJI308 is a selective and potent RSK inhibitor. |
|
