| DC23491 |
ONO-9910539 |
ONO-9910539 is a potent LPA1 inhibitor with IC50 of 22 nM.. |
|
| DC9610 |
ONO-AE3-208 |
ONO-AE3-208(AE 3-208) is an EP4 antagonist; suppresses cell invasion, migration, and metastasis of prostate cancer.
|
|
| DC22705 |
ONO-DI 004 |
ONO-DI 004 is a potent, selective EP1 agonist.. |
|
| DC4243 |
ONX-0914 |
ONX 0914 is an immunoproteasome inhibitor with potential treatment applications in autoimmune disorders, such as rheumatoid arthritis, inflammatory bowel disease and lupus. |
|
| DC10726 |
OPC 21268
Featured
|
OPC-21268 is a vasopressin 1 receptor antagonist potentially for the treatment of heart failure and hypertension. |
|
| DC9404 |
Opicapone
Featured
|
Opicapone(BIA 9-1067) is a long-acting, peripherally selective inhibitor of catechol-O-methyltransferase.
|
|
| DC11905 |
Opiranserin
Featured
|
Opiranserin (VVZ-149, VVZ-000149) is a potent, selective, mixed glycine GlyT2 transporter blocker (IC50= 0.86 uM), purine P2X3 receptor antagonist (IC50=0.87 uM) and serotonin 5-HT2A receptor antagonist (IC50=1.3 uM). |
|
| DC2010 |
Oprozomib (ONX-0912)
Featured
|
Oprozomib (ONX 0912) selectively inhibits CT-L activity of 20S proteasome β5/LMP7 with IC50 of 36 nM/82 nM. |
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|
| DC7262 |
Optovin
Featured
|
Optovin is a reversible photoactive TRPA1 activator. |
|
| DC10702 |
OR59402;NSC 48107
Featured
|
OR59402;NSC 48107 is a bioactive compound. |
|
| DC7425 |
HQL-79 |
Orally active and specific inhibitor of human hematopoietic prostaglandin D synthase (H-PGDS) (IC50 = 6 μM). Antiallergic and anti-inflammatory. |
|
| DC10394 |
Org-26576 |
Org 26576 is a AMPA receptor positive allosteric modulator. |
|
| DC7218 |
Org 27569 |
Org 27569 is an allosteric modulator of cannabinoid CB1 receptor, induces a CB1 receptor state that is characterized by enhanced agonist affinity and decreased inverse agonist affinity. |
|
| DC20483 |
Org 42599 free base |
Org 42599 is a cell-permeant, allosterically binding, small-molecule agonist of luteinizing hormone (LH) receptor that rescues the folding and cell surface expression mutant mutant human LH receptors A593P and S616Y (EC50=70.8 nM).. |
|
| DC21446 |
Org 42599 |
Org 42599 is a cell-permeant, allosterically binding, small-molecule agonist of luteinizing hormone (LH) receptor that rescues the folding and cell surface expression mutant mutant human LH receptors A593P and S616Y (EC50=70.8 nM).. |
|
| DC11203 |
ORIC-101
Featured
|
ORIC-101 (ORIC101) is a highly potent, selective steroidal glucocorticoid receptor (GR) antagonist (IC50=5.6 nM) with reduced androgen receptor (AR) agonistic activity. |
|
| DC21447 |
Orita-13 |
Orita-13 is potent inhibitor of Migration inhibitory factor (MIF) tautomerase activity with Ki of 17 uM.. |
|
| DC8343 |
Oritavancin Diphosphate（LY333328, Orbactiv） |
Oritavancin is a lipoglycopeptide with bactericidal activity against gram-positive bacteria. |
|
| DC11365 |
Oritavancin (phosphate)
Featured
|
Oritavancin is a semisynthetic glycopeptide antibiotic that inhibits the growth of Gram-positive bacteria. |
|
| DCAPI1397 |
Orlistat (Alli, Xenical)
Featured
|
Orlistat is a drug designed to treat obesity. Orlistat's primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. Orlistat is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet. |
|
| DC23573 |
ORM-10962 |
ORM-10962 is a potent, highly selective sodium-calcium exchanger (NCX) inhibitor, significantly reduces inward/outward NCX currents with IC50 of 55 and 67 nM, respectively. |
|
| DC8690 |
ORM-15341(Ketodarolutamide)
Featured
|
ORM-15341 is a potent and full antagonist for human AR (hAR) with IC50 values of 38 nM as shown by transactivation assays in AR-HEK293 cells stably expressing full-length hAR and an androgen-responsive luciferase reporter gene construct. |
|
| DCAPI1297 |
Orotic acid (6-Carboxyuracil) |
Orotic acid (6-Carboxyuracil) |
|
| DC22407 |
Orvepitant |
Orvepitant (GW823296) is a potent and selective, brain penetrant NK1 receptor antagonist with pKi of 10.2. |
|
| DC23149 |
Oseltamivir acid |
Oseltamivir acid (GS 4071, Ro 64-0802, Oseltamivir carboxylate) is a potent inhibitor of influenza neuraminidase (NA) with Ki of <1 nM for both A and B strains,showed potent activity against COVID-19(SARS-COV-2). |
|
| DCAPI1594 |
Oseltamivir phosphate
Featured
|
OSELTAMIVIR is an active (orally) inhibitor of the influenze virus neuraminidase and converted to the active acid metabolite in vivo. |
|
| DC1006 |
OSI-027
Featured
|
OSI-027 is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM, respectively. |
|
| DC8554 |
OSI-420
Featured
|
OSI-420 (Desmethyl Erlotinib,CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for human EGFR and EGFR autophosphorylation in tumor cells. |
|
| DC4105 |
Linsitinib(OSI-906)
Featured
|
OSI-906 (Linsitinib) is a selective inhibitor of IGF-1R and IR with IC50 of 35 nM and 75 nM, respectively. |
|
| DC7219 |
OSI 930
Featured
|
OSI-930 is a potent inhibitor of Kit, KDR and CSF-1R with IC50 of 80 nM, 9 nM and 15 nM, respectively; also potent to Flt-1, c-Raf and Lck and low activity against PDGFRα/β, Flt-3 and Abl. |
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