| DC5040 |
Oclacitinib maleate
Featured
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Oclacitinib, also known as PF03394197, is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. |
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| DC9572 |
Octahydrocurcumin |
Octahydrocurcumin is a hydrogenated derivatives of curcumin; metabolite of curcumin.
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|
| DCAPI1338 |
(+,-)-Octopamine HCl |
Octopamine (OA), a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates. |
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| DC12298 |
Octreotide acetate (SMS 201-995 (acetate))
Featured
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Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently. |
|
| DC20635 |
Odalasvir |
Odalasvir (ACH-3102, JNJ-64289901) is a potent, second-generation HCV NS5A inhibitor in development for the treatment of hepatitis C.. |
|
| DC6401 |
Odanacatib (MK 0822)
Featured
|
Odanacatib (MK 0822) is a potent, selective, and neutral inhibitor of human and rabbit cathepsin K with IC50 of 0.2 nM and 1 nM , respectively. |
|
| DC8700 |
ODM-201(Darolutamide)
Featured
|
ODM-201 is a potent and full antagonists for human AR (hAR) with IC50 values of 26 nM by transactivation assays in AR-HEK293 cells. |
|
| DC12445 |
ODM-203
Featured
|
ODM-203 (ODM203) is a potent, selective, dual inhibitor of FGFR and VEGFR tyrosine kinases with approximately equal potency towards recombinant FGFR1, 2, 3 and 4, as well as VEGFR1, 2 and 3 (IC50=5-35 nM). |
|
| DC21643 |
ODQ |
ODQ (sGC inhibitor ODQ) is a potent, selective, irreversible inhibitor of sGC (soluble guanylyl cyclase). |
|
| DC7850 |
OF-1
Featured
|
OF-1 is a potent inhibitor of BRPF1B and BRPF2 bromodomain with Kd of 100 nM and 500 nM, respectively. |
|
| DC12135 |
Officinalisinin I |
Officinalisinin I is a steroidal saponin, isolated from Anemarrhena asphodeloides. |
|
| DC12526 |
OGG1 inhibitor O8
Featured
|
OGG1 inhibitor O8 is a potent, selective inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1) with IC50 of 0.22 uM, displays no significant activity against other DNA Glycosylases (NEIL1, NTH1, Fpg, IC50>50 uM).. |
|
| DC5204 |
OG-L002
Featured
|
OG-L002 is a potent and specific LSD1 inhibitor with IC50 of 20 nM, exhibiting 36- and 69-fold selectivity over MAO-B and MAO-A, respectively. |
|
| DC9583 |
Oglemilast
Featured
|
Oglemilast(GRC3886) is a potent PDE4 inhibitor, under clinical studies in the treatment of allergen-induced asthma.
|
|
| DC12452 |
OGT inhibitor 4a |
OGT inhibitor 4a (OSMI-4 active form) is a novel potent, selective O-linked N-acetylglucosamine transferase (OGT) inhibitor with Kd of 8 nM, the active form of OSMI-4.. |
|
| DC21439 |
OHM1 |
OHM1 is a potent HIF1α mimic that binds to CH1 domain of p300/CBP with Kd of 500 nM, reduces the level of HIF1α transcriptional activity under hypoxia to that observed under normoxia at 20 uM in A549 cells. |
|
| DC9985 |
OICR9429
Featured
|
OICR-9429 is a potent and selective chemical probe suitable to help dissect the biological role of WDR5 (Kdisp < 100 nM). |
|
| DC11096 |
Olacaftor |
Olacaftor (VX-440, VX440) is a next-generation CFTR corrector, showsthe potential to enhance the amount of CFTR protein at the cell’s surface and for treatment of cystic fibrosis.. |
|
| DC20193 |
Olanexidine Hydrochloride semihydrate;OPB-2045, OPB-2045G |
Olanexidine is a monobiguanide compound with bactericidal activity. |
|
| DC9059 |
Olanzapine
Featured
|
Olanzapine(LY170053) is a high affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist. |
|
| DC4110 |
AZD-2281 (Olaparib)
Featured
|
Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1 and PARP2 with IC50 of 5 nM and 1 nM, respectively. |
|
| DC10370 |
Olcegepant hydrochloride |
Olcegepant hydrochloride is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and with a Ki of 14.4 pM for human CGRP. |
|
| DC9396 |
Olcegepant
Featured
|
Olcegepant(BIBN 4096; BIBN 4096BS) is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor(IC50= 0.03 nM).
|
|
| DC12241 |
Oleamide |
Oleamide is an endogenous fatty acid amide which can be synthesized de novo in the mammalian nervous system, and has been detected in human plasma. |
|
| DC8869 |
Oleuropein |
Oleuropein is an antioxidant polyphenol isolated from olive leaf. |
|
| DC23082 |
Oliceridine hydrochloride |
Oliceridine hydrochloride (Olinvo, TRV130) is a potent, selective, and G protein biased μ opioid receptor (MOR) agonist with pEC50 of 8.1. |
|
| DC23372 |
Olinone
Featured
|
Olinone is a selective inhibitor for the BET BRD1 with Kd of 3.4/3.7/8.6 uM for BRD4-BrD1/BRD3-BrD1/BRD2-BrD1, respectively, shows high selectivity over BET BRD2 (Kd>300 uM). |
|
| DCAPI1464 |
Olmesartan |
Olmesartan Acid is an angiotensin II receptor antagonist that prevents the binding of angiotensin II, thus preventing vasoconstriction. |
|
| DC9179 |
Olmesartan MedoxoMil |
Olmesartan medoxomil(Olmetec; Benicar; CS 866) is an angiotensin II receptor antagonist which is used as an anti-hypertensive. |
|
| DC10384 |
Olodaterol
Featured
|
Olodaterol (BI1744) is a long acting β2-adrenoceptor agonist with an EC50 of 1.4±0.08 nM. |
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