Cat. No. | Product name | CAS No. |
DC10657 |
COTI-2
Featured
COTI-2 is a small molecule candidate anti-cancer drug which can convert mutant p53 to wild-type conformation. |
1039455-84-9 |
DC11726 |
DS-3032b
Featured
DS-3032b is a potent, selective, orally available MDM2-p53 inhibitor with potential antineoplastic activity. |
1398568-47-2 |
DC10400 |
Ecteinascidin 770
Ecteinascidin 770 (ET-770) is a 1,2,3,4-tetrahydroisoquinoline alkaloid with potent anti-cancer activities; inhibits U373MG cells with an IC50 of 4.83 nM. |
114899-80-8 |
DC3156 |
Elesclomol (STA-4783)
Featured
Elesclomol (STA-4783) is a novel potent oxidative stress inducer that illicits pro-apoptosis events among tumor cells.. |
488832-69-5 |
DC9762 |
Emricasan
Featured
Emricasan (IDN-6556, PF-03491390) is a potent irreversible pan-caspase inhibitor. |
254750-02-2 |
DC10742 |
Ferrostatin-1 (Fer-1)
Featured
Ferrostatin-1 is a selective inhibitor of erastin induced ferroptosis with EC50 value of 60 nM. |
347174-05-4 |
DC10522 |
FIN56
Featured
FIN56 is a specific inducer of ferroptosis. |
1083162-61-1 |
DC10972 |
Flavokawain B
Flavokawain B is a natural chalcone that can induce apoptosis in androgen receptor-negative, hormone-refractory prostate cancer cell lines (IC50=3-50 uM), via up-regulation of death-receptor 5 and Bim expression. |
1775-97-9 |
DC10447 |
FX1
Featured
FX1 is a novel specific inhibitor of the B cell lymphoma 6 (BCL6). |
1426138-42-2 |
DC10133 |
Gambogic Acid
Featured
Gambogic Acid activates caspases with EC50 of 0.78-1.64 μM and competitively inhibits Bcl-xl, Bcl-2, Bcl-w, Bcl-B, Bfl-1 and Mcl-1 with IC50 of 1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, 1.06 μM and 0.79 μM, respectively. |
2752-65-0 |
DCAPI1148 |
Gossypol
Gossypol |
303-45-7 |
DC10787 |
GSK2982772
Featured
GSK2982772 is a potent and ATP competitive RIP1 inhibitor with an IC50 of 16 nM. |
1622848-92-3 |
DC9721 |
GSK2983559 active metabolite
Featured
GSK2983559 active metabolite is an active metabolite of GSK2983559. GSK2983559 active metabolite is a receptor interacting protein-2 (RIP2) kinase inhibitor extracted from patent WO/2014043446 A1, compound example 1. |
1423186-80-4 |
DC9733 |
GSK583
Featured
GSK583 is a Highly Potent and Selective Inhibitor of RIP2 Kinase (RIP2K bing IC50=5 nM; rat in vivo PD IC50 = 50 nM). |
1346547-00-9 |
DC10471 |
GSK-872
Featured
GSK-872 is a potent and selective RIPK3 (receptor-interacting protein kinase-3) inhibitor. |
1346546-69-7 |
DC1066 |
HA14-1
Featured
HA14-1 is a nonpeptidic ligand of a Bcl-2 surface pocket with IC50 of~9 μM. |
65673-63-4 |
DC10613 |
NVP-HDM201(Siremadlin )
Featured
HDM201 is an orally bioavailable human double minute 2 homolog (HDM2) inhibitor with potential antineoplastic activity. |
1448867-41-1 |
DC12045 |
HS-1371
Featured
HS-1371 is a novel kinase inhibitor of RIP3-mediated necroptosis. |
2158197-70-5 |
DC11128 |
HS148
Featured
HS148 (DAPK3 inhibitor HS148) is a selective DAPK3 inhibitor with Ki of 119 nM, >10-fold selectivity over Pim kinases.. |
1892595-16-2 |
DC11126 |
HS56
HS56 (Pim-DAPK3 inhibitor HS56) is a potent, dual Pim/DAPK3 inhibitor with Ki of 72 nM (Pim-3) and 315 nM (DAPK3), shows micromolar potency toward Pim-1 and Pim-2 (Ki=1.5 and 17 uM). |
922050-57-5 |
DC11127 |
HS94
Featured
HS94 (DAPK3 inhibitor HS94) is a selective DAPK3 inhibitor with Ki of 126 nM, >20-fold selectivity over Pim kinases.. |
1892594-93-2 |
DC10361 |
Iberin
Featured
Iberin, a sulfoxide analogue of sulforaphane, is a naturally occurring member of isothiocyanate family. It inhibits cell survival with an IC50 of 2.3 μM in HL60 cell. |
505-44-2 |