Cat. No. | Product name | CAS No. |
DC8397 |
AMG 925
Featured
AMG 925 is a potent and selective dual inhibtor of CDK4/FLT3 with IC50s of 1.5 nM and 2.4 nM for CDK4 and FLT3, respectively; with IC50 of 19 nM in MOLM-13 cell. |
1401033-86-0 |
DC5083 |
Cinacalcet (AMG-073) HCl
Featured
AMG-073 HCl (Cinacalcet HCl) represents a new class of compounds for the treatment of hyperparathyroidism. |
364782-34-3 |
DC8514 |
AMG-1
Featured
AMG-1 is a potent inhibitor of human c-Met and RON with IC50 values of 4 and 9 nmol/L respectively. |
913376-84-8 |
DC7056 |
AMG-208
Featured
AMG-208 is a potent small molecular c-Met inhibitor with an IC50 of 9.3 nM. |
1002304-34-8 |
DC8845 |
AMG337
Featured
AMG-337 is a potent and highly selective small molecule ATP-competitive MET kinase inhibitor. AMG 337 inhibits MET kinase activity with an IC50 of < 5nM in enzymatic assays. |
1173699-31-4 |
DC10101 |
AMG-3969
Featured
AMG-3969 is a potent glucokinase-glucokinase regulatory protein interaction (GK-GKRP) disruptor with an IC 50 of 4 nM. |
1361224-53-4 |
DC7001 |
AMG-47a
Featured
AMG-47a is a potent inhibitor of Lck and T cell proliferation; exhibits anti-inflammatory activity (ED50 = 11 mg/kg) in the anti-CD3 induced production of IL-2 in mice. |
882663-88-9 |
DC20664 |
AMG-548
Featured
AMG-548 is a potent and selective inhibitor of p38α with Ki of 0.5 nM, dispalys weak inhibition for p38β (Ki=3.6 nM), and >5,000-fold selectivity over p38γ and p38δ; shows >1,000-fold selectivity over other 36 kinases, and is efficacious in acute and chro |
864249-60-5 |
DC10132 |
AMG9810
Featured
AMG9810 is a potent and selective, competitive vanilloid TRPV1 receptor antagonist (IC50 = 17 nM). |
545395-94-6 |
DC8503 |
AMG-Tie2-1
Featured
AMG-Tie2-1 is a highly potent, non-selective inhibitor of Tie-2 (IC50 <1 nM). |
870223-96-4 |
DC8292 |
AMI-1
Featured
AMI-1 is a PRMT and HIV-1 RT polymerase inhibitor. |
20324-87-2 |
DCAPI1279 |
Aminocaproic acid (Amicar)
Featured
Aminocaproic acid (Amicar)is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders. |
60-32-2 |
DC20178 |
Pyrrolidinedithiocarbamate ammonium;APDC, PDTC
Featured
Ammonium pyrrolidine dithiocarbamate (PDTC) is a potent nuclear factor-κB (NF-κB) inhibitor that inhibits IκB phosphorylation, blocks NF-κB translocation to the nucleus and reduces the expression of downstream cytokines. |
5108-96-3 |
DCAPI1343 |
Amorolfine HCl
Featured
Amorolfine hydrochloride is a antifungal reagent. |
78613-38-4 |
DC10698 |
Amoscanate
Featured
Amoscanate(nithiocyamine) is an experimental anthelmintic agent of the arylisothiocyanate class which was found to be highly effective in animals against the four major species of schistosomes which infect humans,and is also highly active against hookworm |
100990-46-3 |
DC5075 |
BDP-12(Ampalex)
Featured
Ampalex (Ampakine CX516) is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator as a treatment for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI). |
154235-83-3 |
DC11274 |
AMPPD
Featured
AMPPD, 1,2-dioxo-cyclohexane derivatives, is a new biochemistry ultrasensitive alkaline phosphatase substrate. |
122341-56-4 |
DC7324 |
Amuvatinib (MP-470)
Featured
Amuvatinib (MP-470) is a potent and multi-targeted inhibitor of c-Kit, PDGFRα and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively. |
850879-09-3 |
DC25088 |
Rivastigmine
Featured
An acetylcholinesterase (AChE) inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase. |
123441-03-2 |
DC11651 |
HLY-78
Featured
HLY78 is an activator of the Wnt/β-catenin signaling pathway, which targets the DIX domain of Axin and potentiates the Axin-LRP6 association to promote Wnt signaling transduction[1]. |
854847-61-3 |
DC23227 |
N6-Cyclohexyladenosine
Featured
An adenosine A1 receptor agonist (EC50= 8.2 nM).. |
36396-99-3 |
DC24145 |
G-418 disulfate
Featured
An aminoglycoside antibiotic similar in structure to gentamicin B1. |
108321-42-2 |