Cat. No. | Product name | CAS No. |
DC8072 |
Altiratinib(DCC-2701)
Featured
Altiratinib is a MET/TIE2/VEGFR2/TRK (A,B,C) kinase inhibitor in Phase 1 clinical development for the treatment of invasive solid tumors including glioblastoma. |
1345847-93-9 |
DC7079 |
Alvelestat (AZD9668)
Featured
Alvelestat (AZD9668) is a novel, oral inhibitor of neutrophil elastase (NE) with the pIC50 of 7.9 for Human NE. |
848141-11-7 |
DC10209 |
ALW-II-41-27
Featured
ALW-II-41-27 is a novel Eph receptor tyrosine kinase inhibitor, used for cancer treatment. |
1186206-79-0 |
DC23604 |
ALX-5407 hydrochloride
Featured
ALX-5407 is a potent, selective, orally active inhibitor of GlyT1 glycine transporter with IC50 of 3 nM. |
200006-08-2 |
DC11301 |
ALZ-801
Featured
ALZ-801 is a potent and orally available small-molecule β-amyloid (Aβ) anti-oligomer and aggregation inhibitor, valine-conjugated prodrug of Tramiprosate with substantially improved PK properties and gastrointestinal tolerability compared with the parent compound. ALZ-801 is an advanced and markedly improved candidate for the treatment of alzheimer’s disease. |
1034190-08-3 |
DC11289 |
AM-0466
Featured
AM-0466 is a potent and selective NaV1.7 Inhibitor (Nav 1.7 IC50 = 21 nM; Nav 1.5 IC50 =>30.0 uM. PXR = 22% @10 uM; CYP 2C9 IC50 = 4.6 uM; CYP3A4 TDI IC50 =>50.0 uM.). |
1642113-59-4 |
DC8622 |
AM095 free acid
Featured
AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively. |
1228690-36-5 |
DC9909 |
AM2099
Featured
AM-2099 is a potent and selective NaV1.7 Inhibitor. |
1443373-17-8 |
DC12230 |
AM211
Featured
AM211 is a potent, selective and orally bioavailable prostaglandin D2 (PGD2) receptor type 2 (DP2) antagonist |
1175526-27-8 |
DC9830 |
AM-2394
Featured
AM-2394 is a potent and selective Glucokinase agonist (GKA), which catalyzes the phosphorylation of glucose to glucose-6-phosphate. |
1442684-77-6 |
DC8765 |
AM251
Featured
AM251 is a potent CB1 receptor antagonist (IC50 = 8 nM, Ki = 7.49 nM) that displays 306-fold selectivity over CB2 receptors; also potent GPR55 agonist (EC50 = 39 nM). |
183232-66-8 |
DC8886 |
Iodopravadoline(AM-630)
Featured
AM630 is a selective CB2 receptor antagonist that binds to CB1 and CB2 receptors with Ki values of 5.2 µM and 31.2 nM, respectively. |
164178-33-0 |
DC8623 |
AM966
Featured
AM966 is a high affinity, selective, oral LPA1 (lysophosphatidic acid receptor, IC50=17 nM) antagonist, with selectivity for this receptor over the other LPA receptors. |
1228690-19-4 |
DC10372 |
Amcasertib(BBI503)
Featured
Amcasertib(BBI503) is an orally administered investigational agent designed to inhibit cancer stem cell pathways, including Nanog, by targeting stemness kinases. |
1129403-56-0 |
DC5056 |
AMD3465
Featured
AMD3465 is a Potent, selective CXCR4 antagonist; exhibits 8-fold higher affinity than AMD 3100 (Cat.No. 3299). Inhibits SDF-1α-ligand binding (Ki = 41.7 nM). |
185991-07-5 |
DC10621 |
Amenamevir
Featured
Amenamevir, also known as ASP2151, is a herpes virus helicase-primase inhibitor. |
841301-32-4 |
DC7356 |
Ametantrone
Featured
Ametantrone is a new anthracenedione antineoplastic agents, produced a concentration-dependent inhibition of hepatic microsomal lipid peroxidation. |
64862-96-0 |
DC8618 |
AMG-319
Featured
AMG 319 is an investigational, highly selective, small molecule inhibitor of PI3Kδ that blocks B cell proliferation following BCR stimulation both in vitro and in vivo, inhibits basal AKT phosphorylation, and inhibits proliferation in lymphoid tumor cells |
1608125-21-8 |
DC11239 |
AMG-333
Featured
AMG 333 is a potent and highly selective TRPM8 antagonist with an IC50 of 13 nM. |
1416799-28-4 |
DC7055 |
AMG517
Featured
AMG 517 is a potent and selective TRPV1 antagonist, antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM and 1.3 nM. |
659730-32-2 |
DC7867 |
AMG-837
Featured
AMG 837 is a potent GPR40 agonist(EC50=13 nM) with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents. |
865231-46-5 |
DC9366 |
AMG 900
Featured
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM; >10-fold selective for Aurora kinases than p38α, Tyk2, JNK2, Met and Tie2. |
945595-80-2 |