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Molecular Glues

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Cat. No. Product Name Field of Application Chemical Structure
DC67406 EM12-FS Featured EM12-FS is a bifunctional CRBN modulator that engages cereblon at His353 while functioning as a molecular glue to induce NTAQ1 degradation. Demonstrating favorable pharmacokinetics, it exhibits a human plasma half-life of 196 minutes, supporting its therapeutic potential.
DC67407 IKZF1-degrader-1 Featured IKZF1-degrader-1 (Compound 9-B) is a highly potent molecular glue that achieves sub-nanomolar degradation of IKZF1 (DC50 = 0.134 nM), demonstrating significant therapeutic potential for targeting IKZF1-dependent malignancies.
DC67410 MRT-10350 Featured
DC67411 MRT-7612 Featured
DC67412 MRT-3486 Featured
DC67413 MRT-23227 Featured

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