Novel PROTAC Estrogen-related Receptor α (ERRα) Degrader

Novel Activator of the Anticipatory Unfolded Protein Response with Enhanced Selectivity for Estrogen Receptor Positive Breast Cancer

The first ERβ-targeted near-infrared (NIR) inherently fluorescent probe, showing the advantages of high ERβ selectivity, good optical properties, and excellent ERβ imaging capability in living cells

Carbapenem antibiotic, inhibiting cross-linking of the peptidoglycan layer of bacterial cell walls by blocking penicillin-binding proteins (PBPs)

Novel thermosensitive fluorescent dye, visualizing thermogenesis in stimulated single-cell brown adipocytes

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Novel potent inhibitor of recombinant human and mouse Transglutaminase enzyme activity, mainly TG2 and the close related enzyme TG1

Anti-HBV agent, showing activities on HepG 2.2.15 cell line in vitro

Precursor of adrenaline, suppressing the locomotor stimulation by MAO inhibitor

Broad-spectrum, topical macrolide antibiotic, diffusing through the bacterial cell membrane and reversibly binding to the 50S subunit of the bacterial ribosome

Serotonin 5-HT2A Agonist

Novel Highly Soluble σ1 Receptor Antagonist for Pain Management

Selective estrogen receptor modulator (SERM), exhibiting estrogen agonism in certain tissues and estrogen antagonism in others

Non-Peptidic, potent, and orally active stromelysin inhibitor, blocking cartilage degradation

H-89 analog as PKA and AKT1 inhibitor with specificity on no longer inhibiting CAMK2B and neither affecting viability of mice nor causing any detectable tissuedamage at the dose given

Novel inhibitor of PORCN, inhibiting ß-catenin reporter activity in a dose-dependent manner

Cell-impermeant viability indicator, as high-affinity nucleic acid stain that is weakly fluorescent until bound to DNA and emits red fluorescence (excitation/emission maxima ~528/617).

Novel anticancer agent

Natural potent antiviral agent, significantly inhibiting coxsackievirus group B (CVB) replication both in vivo and in vitro

Novel selective FTO inhibitor

TRPA1 channel agonist

Activator of β2 and β3 subunit containing channels of the GABAA receptor complex, stimulating the production of GABA(A) active neurosteroids