Cat. No. | Product name | CAS No. |
DC10621 |
Amenamevir
Featured
Amenamevir, also known as ASP2151, is a herpes virus helicase-primase inhibitor. |
841301-32-4 |
DC8618 |
AMG-319
Featured
AMG 319 is an investigational, highly selective, small molecule inhibitor of PI3Kδ that blocks B cell proliferation following BCR stimulation both in vitro and in vivo, inhibits basal AKT phosphorylation, and inhibits proliferation in lymphoid tumor cells |
1608125-21-8 |
DC11239 |
AMG-333
Featured
AMG 333 is a potent and highly selective TRPM8 antagonist with an IC50 of 13 nM. |
1416799-28-4 |
DC9366 |
AMG 900
Featured
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM; >10-fold selective for Aurora kinases than p38α, Tyk2, JNK2, Met and Tie2. |
945595-80-2 |
DC5083 |
Cinacalcet (AMG-073) HCl
Featured
AMG-073 HCl (Cinacalcet HCl) represents a new class of compounds for the treatment of hyperparathyroidism. |
364782-34-3 |
DC7056 |
AMG-208
Featured
AMG-208 is a potent small molecular c-Met inhibitor with an IC50 of 9.3 nM. |
1002304-34-8 |
DC9793 |
AMG232
AMG232 is a potent, selective and orally bioavailable inhibitor of MDM2−p53 interaction with IC50 value of 9.1 nM in EdU cells . |
1352066-68-2 |
DC8845 |
AMG337
Featured
AMG-337 is a potent and highly selective small molecule ATP-competitive MET kinase inhibitor. AMG 337 inhibits MET kinase activity with an IC50 of < 5nM in enzymatic assays. |
1173699-31-4 |
DC11878 |
AMG-579
AMG-579 is a potent, selective, CNS penetrant, orally bioavailable PDE10A inhibitor with IC50 of 0.1 nM. |
1227067-61-9 |
DC10132 |
AMG9810
Featured
AMG9810 is a potent and selective, competitive vanilloid TRPV1 receptor antagonist (IC50 = 17 nM). |
545395-94-6 |
DC8923 |
AS-1413(Amonafide)
Amonafide(AS1413) produces protein-associated DNA-strand breaks through a topoisomerase II-mediated reaction, but does not produce topoisomerase I-mediated DNA cleavage. |
69408-81-7 |
DC9406 |
Ampiroxicam
Ampiroxicam(CP65703) is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug. |
99464-64-9 |
DC11076 |
Ampreloxetine
Ampreloxetine (TD-9855) is a potent monoamine reuptake inhibitor with pIC50 of 8.0, 8.6 and 6.8 for human NET, SERT, and DAT, respectively. |
1227056-84-9 |
DC7058 |
Amprenavir
Amprenavir (Agenerase) is a HIV protease inhibitor(Ki=0.6 nM) used to treat HIV infection. |
161814-49-9 |
DC7324 |
Amuvatinib (MP-470)
Featured
Amuvatinib (MP-470) is a potent and multi-targeted inhibitor of c-Kit, PDGFRα and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively. |
850879-09-3 |
DC6311 |
Pomalidomide
Featured
An inhibitor of LPS-induced TNFαrelease.Pomalidomide is thalidomide derivative that displays inhibition of LPS-induced TNFα release. Shows immunomodulator and anticancer effects. |
19171-19-8 |
DC11965 |
Lucanthone
An orally available thioxanthone-based DNA intercalator and inhibitor of the DNA repair enzyme apurinic-apyrimidinic endonuclease 1 (APE1) potential antineoplastic activity, also inhibits autophagy. |
479-50-5 |
DC11738 |
SCYX-7158
An orally-active, CNS permeable benzoxaborole antiprotozoal agent. |
1266084-51-8 |
DC7815 |
Crisaborole(AN-2728)
Featured
AN-2728 is a topically administered, boron-containing, anti-inflammatory compound that inhibits PDE4 activity and thereby suppresses the release of TNFalpha, IL-12, IL-23 and other cytokines. |
906673-24-3 |
DC9827 |
AN3365(Epetraborole)
Featured
AN3365 is a first-in-class antibiotic that demonstrates potent activity across a wide spectrum of Gram-negative bacteria, including those resistant to many other antibiotics. |
1234563-16-6 |
DC7804 |
Anacetrapib(MK0859)
Featured
Anacetrapib (MK0859) is a potent, selective, reversible rhCETP and mutant CETP(C13S) inhibitor with IC50 of 7.9 nM and 11.8 nM, increases HDL-C and decreases LDL-C, does not increase aldosterone or blood pressure. Phase 3. |
875446-37-0 |
DC7357 |
Anamorelin
Featured
Anamorelin(RC1291; ONO-7643) is a synthetic orally active ghrelin receptor agonist which is under development for the management of non-small lung cancer associated cachexia/anorexia. |
249921-19-5 |