Cat. No. | Product name | CAS No. |
DC5064 |
Baricitinib (INCB28050, LY3009104)
Featured
Baricitinib is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2,showed potent activity against COVID-19(SARS-COV-2). |
1187594-09-7 |
DC8258 |
Baricitinib phosphate
Featured
Baricitinib phosphate(INCB 028050; LY 3009104) is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2,showed potent activity against COVID-19(SARS-COV-2). |
1187595-84-1 |
DC9935 |
Basmisanil(RG1662)
Featured
Basmisanil is a highly selective inverse agonist/negative allosteric modulator of α5 subunit-containing GABAA receptors which is under development by Roche for the treatment of cognitive impairment associated with Down syndrome. |
1159600-41-5 |
DC10021 |
Batefenterol
Featured
Batefenterol(GSK961081,TD-5959)is a Muscarinic Antagonist and β2-Agonist possessing both muscarinic antagonist (MA) and β2-adrenoceptor agonist (BA) properties (MABA). |
743461-65-6 |
DC8133 |
Batimastat(BB-94)
Featured
Batimastat was used to study the role of MMP in proteolytic release of EGF in human follicular thyroid carcinoma cell line FTC-133. |
130370-60-4 |
DC12663 |
Bax channel blocker(BAI-1)
Featured
Bax channel blocker is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50 = 0.52 μM). Suggested to inhibit Bax channel formation/activity. |
335165-68-9 |
DC7869 |
BAY11-7082
Featured
BAY 11-7082 is a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation with IC50 of 10 μM. Also inhibiting components of the ubiquitin system. |
19542-67-7 |
DC8038 |
Bay 11-7085
Featured
BAY 11-7085 is an irreversible inhibitor of TNFα-induced IκBα phosphorylation with an IC50 value of 10 μM. |
196309-76-9 |
DC20589 |
BAY 1251152
Featured
BAY 1251152 (VIP152 ) is the first potent, selective, orally available PTEFb/CDK9 inhibitor with biochemical IC50 of 9 nM and MOLM13 cell IC50 of 29 nM, displays> 50-fold selectivity against other CDKs. |
1610358-56-9 |
DC23745 |
BAY-2402234
Featured
BAY 2402234 (BAY2402234) is a novel potent, selective, orally bioavailable DHODH inhibitor with IC50 of 1.2 nM (human full-length DHODH). |
2225819-06-5 |
DC10085 |
Bay 41-4109 (racemate)
Featured
BAY 41-4109 racemate is a potent inhibitor of human hepatitis B virus (HBV) with an IC50 of 53 nM. |
298708-79-9 |
DC7323 |
Pritelivir(BAY-57-1293)
Featured
BAY 57-1293 represents a new class of potent inhibitors of herpes simplex virus (HSV) that target the virus helicase primase complex. |
348086-71-5 |
DC4113 |
Cinaciguat (BAY 58-2667)
Featured
BAY 58-2667 is a nitric oxide (NO)- and heme-independent soluble guanylyl cyclase activator. Displays potent cardiovascular effects. |
329773-35-5 |
DC9783 |
Bay 59-3074
Featured
Bay 59-3074 is a novel CB1/CB2 receptor partial agonist (Ki values are 48.3 and 45.5 nM at human CB1 and CB2 receptors respectively). |
406205-74-1 |
DC9578 |
Bay 60-7550
Featured
Bay 60-7550 is a potent PDE2 inhibitor with IC50 values of 2.0 nM (bovine) and 4.7 nM (human); 50-fold more selective for PDE2 compared to PDE1 and greater than 100-fold selective compared to PDE5, PDE3B, PDE4B, PDE7B, PDE8A, PDE9A, PDE10A, and PDE11A. |
439083-90-6 |
DC9632 |
BAY 61-3606 (dihydrochloride)
Featured
BAY 61-3606 2Hcl is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM) with no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src. |
648903-57-5 |
DC10660 |
BAY 61-3606 free base
Featured
BAY 61-3606 is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM) with no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src. |
732983-37-8 |
DC26066 |
BAY 61-3606 hydrochloride
Featured
BAY 61-3606 is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase with Ki of 7.5 nM, displays no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src. |
1615197-10-8 |
DC9591 |
BAY 80-6946(Copanlisib)
Featured
BAY 80-6946(Copanlisib) is a potent and highly selective reversible PI3K inhibitor for PI3Kα/β with IC50 of 0.469 nM/3.72 nM. |
1032568-63-0 |
DC7996 |
BAY 87-2243
Featured
BAY 87-2243 is a highly potent and selective inhibitor of hypoxia-induced HIF-1 activation. |
1227158-85-1 |
DC23559 |
Bay K-8644
Featured
Bay K-8644 is a potent L-type calcium channels (LTCCs) activator with EC50 of 17.3 nM, has positive inotropic, vasoconstrictive and behavioral effects in vivo. |
71145-03-4 |
DC10408 |
BAY1125976
Featured
BAY1125976 is a selective allosteric Akt1/2 inhibitor; inhibits Akt1 and Akt2 activity with IC50 values of 5.2 nM and 18 nM at 10 μM ATP, respectively. |
1402608-02-9 |