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Cat. No. Product Name Field of Application Chemical Structure
DCAPI1516 Eribulin Eribulin Mesylate (E7389 Mesylate), a synthetic analogue of halichondrin B in phase III clinical trials for breast cancer, binds to tubulin and microtubules.
DC22441 Eritoran tetrasodium Eritoran tetrasodium (E5564) is an investigational drug for the treatment of severe sepsis that acts as a TLR4 antagonist..
DC26018 ERK5-IN-2 Featured ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50s of 0.82 μM, 3 μM for ERK5 and ERK5 MEF2D, respectively.
DC22486 Erlotinib mesylate Featured Erlotinib is an epidermal growth factor receptor inhibitor (EGFR inhibitor). Erlotinib HCl was approved. Erlotinib binds in a reversible fashion to the adenosine triphosphate (ATP) binding site of the receptor. For the signal to be transmitted, two EGFR molecules need to come together to form a homodimer. These then use the molecule of ATP to trans-phosphorylate each other on tyrosine residues, which generates phosphotyrosine residues, recruiting the phosphotyrosine-binding proteins to EGFR to assemble protein complexes that transduce signal cascades to the nucleus or activate other cellular biochemical processes. When erlotinib binds to EGFR, formation of phosphotyrosine residues in EGFR is not possible and the signal cascades are not initiated.
DC2101 Erlotinib free base Featured Erlotinib (OSI-744; NSC 718781; R1415) is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive for EGFR than human c-Src or v-Abl.
DC3139 Erlotinib hydrochloride Featured Erlotinib HCl is an HER1/EGFR inhibitor with IC50 of 2 nM.
DCAPI1477 Ertapenem Featured Ertapenem is a carbapenem antibiotic marketed by Merck as Invanz.
DCAPI1476 Ertapenem Sodium Featured Ertapenem Sodium
DC8440 Erythromycin Cyclocarbonate Featured Erythromycin Cyclocarbonate, derivative of Erythromycin, inhibits protein synthesis of bacteria by binding to the 50S ribosome.
DC7409 E-Mycin Erythromycin, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis.
DC20244 ES9-17 Featured ES9-17 is a novel CME inhibitor.
DC10211 Escin Escin is a mixture of saponins with anti-inflammatory, vasoconstrictor and vasoprotective effects found in Aesculus hippocastanum(the horse chestnut).
DC4171 Escitalopram oxalate Featured Escitalopram Oxalate is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.
DC21000 ESI-05 Featured ESI-05 is a potent EAPC2-specific antagonist that inhibits cAMP-mediated EPAC2 GEF activity with apparent IC50 of 0.43 uM.
DC8443 ESI-09 Featured ESI-09 is a specific exchange protein directly activated by cAMP (EPAC) inhibitor with IC50 of 3.2 μM and 1.4 μM for EPAC1 and EPAC2, respectively, >100-fold selectivity over PKA.
DC9565 Eslicarbazepine (acetate) Eslicarbazepine acetate (BIA 2-093) is an antiepileptic drug.
DC12325 Eslicarbazepine (BIA 2-194) Eslicarbazepine is an oral anticonvulsant indicated for the adjunctive treatment of partial seizures.
DCAPI1423 Esomeprazole Esomeprazole
DCAPI1487 Esomeprazole(magnesium) Esomeprazole(magnesium)
DC10714 Esonarimod (KE-298) Featured Esonarimod (KE-298) is a new antirheumatic drug.
DC23056 esperamicin A1 Featured Esperamicin A1 is an enediyne antitumor antibiotics of bacterial origin.
DCAPI1200 Estradiol Estradiol
DC9440 Estropipate Featured Estropipate is a form of estrogen, used to treat symptoms of menopause, also used to prevent osteoporosis.
DC3162 Eszopiclone Eszopiclone is a nonbenzodiazepine hypnotic which is slightly effective for insomnia.
DC7770 Etamicastat Etamicastat is a novel dopamine β-hydroxylase inhibitor
DC8182 Bempedoic Acid(ETC-1002;ESP-55016) Featured ETC-1002(ESP-55016) is a novel, first-in-class, orally available, once-daily LDL-C lowering small molecule; activator of hepatic AMP-activated protein kinase (AMPK); also has potent inhibitory activity against hepatic ATP-citrate lyase(IC50=29 uM).
DC8489 ETC-159 Featured ETC-159 is a potent and specific inhibitor of Wnt secretion. ETC-159 inhibits _beta_-catenin reporter activity in a dose-dependent manner with an IC50 of 2.9 nM.
DC21003 ETC-206 Featured ETC-206 (ETC-1907206) is a novel potent, selective MNK1/2 inhibitor with IC50 of 64/86 nM, inhibits eIF4E phosphorylation inhibition in HeLa cell line with IC50 of 321 nM.
DC8123 ETH 157(Sodium ionophore II) Featured ETH 157(Sodium ionophore II)is a neutral ionophore for liquid-membrane electrodes of high selectivity for Na+.
DC9016 Etamsylate Ethamsylate is a haemostatic drug, also inhibits biosynthesis and action of those prostaglandins.

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