Cat. No. | Product name | CAS No. |
DC9531 |
SMND-309
SMND-309 is a novel derivative of salvianolic acid B, and has shown protective effects against rat cortical neuron damage in vitro and in vivo. |
1065559-56-9 |
DC23887 |
M25
Smo antagonist M25 is a potent Smoothened (Smo) receptor antagonist (IC50=5 nM) that inhibits the Hedgehog signaling pathway. |
1186293-14-0 |
DC20555 |
Smoothib
Smoothib is a novel potent inhibitor of hedgehog (Hh) signaling (IC50=157±118 nM) and an antagonist of the protein smoothened (Smo), binds to the heptahelical bundle of Smo with Kd of 59 nM. |
2141958-94-1 |
DC12437 |
SMU127
SMU127 (SMU-127, ZINC666243) is a specific TLR1-TLR2 small molecule agonist with EC50 of 0.55 uM. |
903864-87-9 |
DC9622 |
SN 2
SN 2 is a novel and potent small molecule activator of TRPML3 with EC50 of 1.13 uM. |
823218-99-1 |
DC11796 |
SN-32976
SN-32976 is a novel, potent and selective class I PI3K and mTOR inhibitor with IC50 of 15.1/461/110/134/194 nM for PI3Kα/PI3Kβ/PI3Kγ/PI3Kδ/mTOR, respectively. |
1246202-11-8 |
DC12597 |
SN79 dihydrochloride
SN79 dihydrochloride (Sigma receptor ligand SN79) is a putative σ receptor antagonist with nanomolar affinity and selectivity for σ receptors over 57 other binding sites. |
1121928-95-7 |
DC21670 |
SNAP-7941
SNAP-7941 is a selective, high-affinity, and competitive MCH1 receptor (MCH1-R) antagonist with Ki of 15 nM. |
387825-78-7 |
DC21671 |
SNAP-94847
SNAP-94847 is a selective, high-affinity, and competitive MCH1 receptor (MCH1-R) antagonist with Ki of 1.69 nM. |
|
DC21672 |
SNAP-94847 hydrochloride
Featured
SNAP-94847 is a selective, high-affinity, and competitive MCH1 receptor (MCH1-R) antagonist with Ki of 1.69 nM. |
487051-12-7 |
DC11584 |
SNIPER(ABL)-062
SNIPER(ABL)-062 is a novel, potent SNIPER molecule that tethers BCR-ABL inhibitor to a ligand of IAP, causes potent BCR-ABL degradation. |
2140260-89-3 |
DC22792 |
SNIPER(AR)-51
SNIPER(AR)-51 is a specific and nongenetic, protein degradation inducer of androgen receptor, consistiong of AR ligand and IAP ligand and linker. |
2113688-43-8 |
DC21953 |
SNIPER(ER)-110
SNIPER(ER)-110 is a nongenetic IAP-dependent protein eraser (SNIPER) targeting estrogen receptor α (ERα), induces ERα degradation and induces apoptosis in MCF-7 human breast cancer cells. |
|
DC11318 |
SNVP
SNVP is an S-nitrosothiol that acts as a nitric oxide (NO) donor and vasodilator. |
225233-99-8 |
DC21674 |
SNX-0723
SNX-0723 is a selective, brain-permeable, orally acitve small-molecule inhibitor of Hsp90 (IC50=14 nM) that inhibits alpha-synuclein oligomerization with EC50 of 48 nM. |
1073969-18-2 |
DC5133 |
SNX-2112 (PF-04928473)
Featured
SNX-2112 selectively binds to the ATP pocket of HSP90α and HSP90β with Ka of 30 nM and 30 nM, uniformly more potent than 17-AAG. |
908112-43-6 |
DC23803 |
SNX-9114
SNX-9114 (SNX9114, PF-04944733) is a small molecule Hsp90 inhibitor with excellent brain permeability.. |
1621990-48-4 |
DC9539 |
Sobetirome
Sobetirome(GC-1; QRX-431) is a member of a class of compounds known as selective thyromimetics. |
211110-63-3 |
DC11020 |
SOD1-Derlin-1 inhibitor 56-59
SOD1-Derlin-1 inhibitor 56-59 is a cell-permeable, small molecule inhibitor of SOD1-Derlin-1 interaction, target SOD1 DBR and clearly attenuates the interactions of Derlin-1 with 122 types of SOD1mut in the cell-based co-immunoprecipitation assay. |
2170170-27-9 |
DC9540 |
sodium 4-pentynoate
sodium 4-pentynoate is a alkynylacetate analogue; can be metabolically incorporated onto cellular proteins through biosynthetic mechanisms for profiling of acetylated proteins in diverse cell types. |
101917-30-0 |
DC7287 |
Ralfinamide
Featured
Sodium channel blocker. Suppresses tetrodotoxin (TTX)-resistant Na+ currents approximately twice as selectively as TTX-sensitive currents. Antinociceptive; displays analgesic effects in animal models of inflammatory and neuropathic pain. |
202825-45-4 |
DC7505 |
Sodium-Channel-inhibitor-1
Sodium Channel inhibitor1, one of 3-Oxoisoindoline-1-carboxamides, is a novel and selective voltage-gated sodium channel for pain treatment. |
1198117-23-5 |