Cat. No. | Product name | CAS No. |
DC23451 |
SKF-38393 hydrobromide
SKF-38393 is a potent, selective D1/D5 receptor partial agonist with Ki of 1 and 0.5 nM, respectively. |
67287-49-4 |
DC7834 |
SKF 89976A HCl
Featured
SKF-89976A was used to study the role of adenosine receptors in uptake of GABA transport. |
85375-15-1 |
DC21659 |
SKI-178
Featured
SKI-178 is a potent, specific, non-lipid SphK1 inhibitor with Ki of 1.33 uM, displays no significant activity for SphK2 (IC50>25 uM). |
1259484-97-3 |
DC7501 |
SKLB1002
Featured
SKLB1002 is a novel and potent VEGFR-2 inhibitor with an IC50 value of 32 nM. |
1225451-84-2 |
DC21660 |
SKLB188
SKLB188 is a novel multikinase inhibitor and potently inhibits EGFR with IC50 of 5 nM. |
1350545-09-3 |
DC12619 |
SKLB-C05
SKLB-C05 is a novel selective, orally active TOPK inhibitor with IC50 of 0.5 nM, shows excellent cytotoxicity and anti-migration and invasion activity on TOPK high-expressing CRC cells and induces cell apoptosis. |
|
DC8239 |
SL 0101-1
SL 0101-1 is a selective inhibitor of p90 Rsk (ribosomal S6 kinase) (IC50 = 89 nM for Rsk-2). |
77307-50-7 |
DC20552 |
SLC25A20-IN-21
SLC25A20-IN-21 is a SLC25A20 ligand that increases long-chain (>C14) acylcarnitine content and reduces maximal exogenous fatty acid oxidation in HSC-5 cells. |
1241469-17-9 |
DC12314 |
SLLK, Control Peptide for TSP1 Inhibitor(TFA)
Featured
SLLK, Control Peptide for TSP1 Inhibitor (TFA) is a control peptide for LSKL, which is a Thrombospondin (TSP-1) inhibitor. |
464924-27-4 |
DC22005 |
SLLN-15
SLLN-15 (Autophagy inducer SLLN-15) is a potent, orally available inducer of autophagy that selectively activated cytostatic macroautophagy/autophagy in TNBC preclinical models, promotes AURKA degradation and . |
|
DC23294 |
SM-1295
SM-1295 is a potent, selective cIAP1 and cIAP2 inhibitor with Ki of <10 nM, displays >900-fold for cIAP1 over XIAP. |
1562375-46-5 |
DC23295 |
SM13
SM13 is a novel small molecule that blocks p53-MDM2 interaction and induces apoptosis both in vitro and in vivo. |
1445992-93-7 |
DC11879 |
SM253
SM253 (SM 253, SM-253) is a novel potent Hsp90 inhibitor that does not induce heat shock response. |
1610546-52-5 |
DC22723 |
SM-324405
SM-324405 is a potent, selective TLR7 agonist with EC50 of 50 nM, induces IFN-α and -γ expression in human PBMCs and mouse splenocytes, inhibits IL-5 production in human PBMCs in vitro.. |
677773-91-0 |
DC21662 |
SMAP-2
SMAP-2 (DT-1154) is an orally bioavailable small molecule activator of PP2A, binds to PP2A Aα scaffold subunit and inhibits KRAS-driven tumor growth both in vitro and in vivo. |
1809068-70-9 |
DC20762 |
SMARt-420
SMARt-420 (BDM 41420) is a small molecule that can fully reverses ethionamide-acquired resistance and clears ethionamide-resistant M. tuberculosis infection in mice, also increases the basal sensitivity of bacteria to ethionamide.. |
1616242-21-7 |
DC7895 |
SMER3(SMER 3)
SMER3 is a selective inhibitor of a yeast SCF family E3 ubiquitin ligase (SCFMet30) in vitro and in vivo. |
67200-34-4 |
DC21664 |
SMIFH2
Featured
SMIFH2 is a small molecule formin homology 2 domains inhibitor of formin-mediated actin assembly, targets formins from evolutionarily diverse organisms including yeast, nematode worm, and mice with IC50s of 5-15 uM. |
340316-62-3 |
DC7152 |
SMIP004
SMIP004 is a novel inducer of cancer-cell selective apoptosis of human prostate cancer cells, it was found to downregulate SKP2 and to stabilize p27. |
143360-00-3 |
DC22462 |
SMN2 modulator 27
SMN2 modulator 27 is a novel SMN2 modulator that stabilize the SMN protein with EC50 of 0.29 uM. |
1537150-15-4 |
DC20553 |
SMN-C2
SMN-C2 is a close analogs of RG-7916 act as selective RNA-binding ligands that modulate pre-mRNA splicing. |
1446311-56-3 |
DC20554 |
SMN-C3
SMN-C3 is a selective, orally available small molecule SMN2 splicing modifier toward the production of full-length SMN2 messenger RNA with high selectivity. |
1449597-34-5 |