SKF-38393 is a potent, selective D1/D5 receptor partial agonist with Ki of 1 and 0.5 nM, respectively.

SKF-89976A was used to study the role of adenosine receptors in uptake of GABA transport.

SKI-178 is a potent, specific, non-lipid SphK1 inhibitor with Ki of 1.33 uM, displays no significant activity for SphK2 (IC50>25 uM).

SKLB1002 is a novel and potent VEGFR-2 inhibitor with an IC50 value of 32 nM.

SKLB188 is a novel multikinase inhibitor and potently inhibits EGFR with IC50 of 5 nM.

SKLB-C05 is a novel selective, orally active TOPK inhibitor with IC50 of 0.5 nM, shows excellent cytotoxicity and anti-migration and invasion activity on TOPK high-expressing CRC cells and induces cell apoptosis.

SL 0101-1 is a selective inhibitor of p90 Rsk (ribosomal S6 kinase) (IC50 = 89 nM for Rsk-2).

SLC25A20-IN-21 is a SLC25A20 ligand that increases long-chain (>C14) acylcarnitine content and reduces maximal exogenous fatty acid oxidation in HSC-5 cells.

SLLK, Control Peptide for TSP1 Inhibitor (TFA) is a control peptide for LSKL, which is a Thrombospondin (TSP-1) inhibitor.

SLLN-15 (Autophagy inducer SLLN-15) is a potent, orally available inducer of autophagy that selectively activated cytostatic macroautophagy/autophagy in TNBC preclinical models, promotes AURKA degradation and .

SM-1295 is a potent, selective cIAP1 and cIAP2 inhibitor with Ki of <10 nM, displays >900-fold for cIAP1 over XIAP.

SM13 is a novel small molecule that blocks p53-MDM2 interaction and induces apoptosis both in vitro and in vivo.

SM253 (SM 253, SM-253) is a novel potent Hsp90 inhibitor that does not induce heat shock response.

SM-324405 is a potent, selective TLR7 agonist with EC50 of 50 nM, induces IFN-α and -γ expression in human PBMCs and mouse splenocytes, inhibits IL-5 production in human PBMCs in vitro..

SMAP-2 (DT-1154) is an orally bioavailable small molecule activator of PP2A, binds to PP2A Aα scaffold subunit and inhibits KRAS-driven tumor growth both in vitro and in vivo.

SMARt-420 (BDM 41420) is a small molecule that can fully reverses ethionamide-acquired resistance and clears ethionamide-resistant M. tuberculosis infection in mice, also increases the basal sensitivity of bacteria to ethionamide..

SMER3 is a selective inhibitor of a yeast SCF family E3 ubiquitin ligase (SCFMet30) in vitro and in vivo.

SMIFH2 is a small molecule formin homology 2 domains inhibitor of formin-mediated actin assembly, targets formins from evolutionarily diverse organisms including yeast, nematode worm, and mice with IC50s of 5-15 uM.

SMIP004 is a novel inducer of cancer-cell selective apoptosis of human prostate cancer cells, it was found to downregulate SKP2 and to stabilize p27.

SMN2 modulator 27 is a novel SMN2 modulator that stabilize the SMN protein with EC50 of 0.29 uM.

SMN-C2 is a close analogs of RG-7916 act as selective RNA-binding ligands that modulate pre-mRNA splicing.

SMN-C3 is a selective, orally available small molecule SMN2 splicing modifier toward the production of full-length SMN2 messenger RNA with high selectivity.