Cat. No. | Product name | CAS No. |
DCAPI1349 |
Simvastatin (Zocor)
Featured
Simvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM. |
79902-63-9 |
DC20146 |
Sinapinic acid (Sinapic acid)
Featured
Sinapinic acid (Sinapic acid) is a phenolic compound isolated from Hydnophytum formicarum Jack. Rhizome, acts as an inhibitor of HDAC, with an IC50 of 2.27 mM, and also inhibits ACE-I activity. Sinapinic acid posssess potent anti-tumor activity, induces a |
530-59-6 |
DC22525 |
Sincalide
Sincalide (CCK-8) is a 8-amino acid C-terminal fragment of cholecystokinin. |
25126-32-3 |
DC11072 |
SINCRO
SINCRO is a novel anti-cancer compound that can activate the cytosolic DNA-sensing STING signaling pathway leading to the induction of type I interferon (IFN) genes. |
1494619-28-1 |
DC20608 |
Sinefungin
Sinefungin (A 9145. |
58944-73-3 |
DC21419 |
Siomycin A
Siomycin A (NSC 285116) is an antibiotic thiazole inhibitor of the oncogenic transcription factor FOXM1, down-regulates the transcriptional activity as well as the protein and mRNA abundance of FoxM1. |
12656-09-6 |
DC8867 |
SirReal2
SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM. |
709002-46-0 |
DC12586 |
SirT1 enhancer A03
SirT1 enhancer A03 is a specific, orally bioavailable, brain penetrant apolipoprotein E4 (ApoE4)-targeted sirtuin1 (SirT1) enhancer, increases the levels of the neuroprotective enzyme SirT1 while not affecting levels of neurotoxic SirT2 in vitro in ApoE4- |
66171-75-3 |
DC23365 |
AEM2
SIRT2 inhibitor AEM2 (AEM2) is a selective SIRT2 inhibitor with IC50 of 3.8 uM, shows only weak effects on other sirtuins such as SIRT1, SIRT3, and yeast Sir2. |
1005095-04-4 |
DC12109 |
SIRT5 inhibitor
SIRT5 inhibitor is a potent Human Sirtuin 5 deacylase inhibitor, with an IC50 of 0.11 μM. |
2166487-21-2 |
DC5112 |
Sitagliptin (Metformin,MK-0431)
Sitagliptin phosphate (MK-0431) is a potent inhibitor of DPP-IV with IC50 of 19 nM in Caco-2 cell extracts. |
486460-32-6 |
DC10632 |
Sitravatinib (MGCD516)
Featured
Sitravatinib (MGCD516) is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Kit, PDGFRβ, PDGFRα, c-Met, and Axl. |
1123837-84-2 |
DC9506 |
SJ-172550
Featured
SJ-172550 is the first MDMX inhibitor with EC50 of 0.84 uM; binds reversibly to MDMX and effectively kills retinoblastoma cells in which the expression of MDMX is amplified. |
431979-47-4 |
DC20591 |
SJ-733
SJ-733 (SJ000557733. |
1424799-20-1 |
DC21654 |
SJ830599
SJ830599 is a modest selective BRD2-BD2 inhibitor with IC50 of 0.61 uM, 3.3-fold selectivity over BRD2-BD1. |
2215098-23-8 |
DC21655 |
SJB7
SJB7 is a close analog of SPA70 and hPXR agonist, interacts with the ligand-binding domain (LBD) of hPXR.. |
2135395-15-0 |
DC22450 |
SK 216
SK 216 is a potent, selective inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 44 uM. |
654080-03-2 |
DC23427 |
SK609(SK-609;SK 609;ES609)
SK609 (SK-609, ES609) is a potent, selective agonist of dopamine D3 receptor with a bias towards the G-protein-dependent pathway rather than recruiting β-arrestin-2 and an EC50 value of 113.9 nM for activation of ERK1/2 phosphorylation. |
1092797-77-7 |
DC11376 |
SKA-121
Featured
SKA-121 is a positive-gating modulator of intermediate-conductance calcium-activated potassium channels (IKCa1/KCa3.1) with an EC50 value of 109 nM using whole-cell patch-clamp electrophysiology with calcium in the internal solution. |
1820708-73-3 |
DC20104 |
Skatole
Featured
Skatole is produced by intestinal bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38. |
83-34-1 |
DC9420 |
SKF-82958 (hydrobromide)
SKF 82958 hydrobromide is a D1/D5 receptor full agonist. |
74115-01-8 |
DC8859 |
SKF38393 HCl
Featured
SKF38393 HCl is a selective dopamine D1/D5 receptor agonist. |
62717-42-4 |