Cat. No. | Product name | CAS No. |
DC23764 |
TBOPP
TBOPP is a selective inhibitor of Rac-specific guanine nucleotide exchange factor DOCK1, inhibits DOCK1-mediated Rac activation with IC50 of 8.4 uM. |
1996629-79-8 |
DC21739 |
TBZE-029
TBZE-029 is a selective inhibitor of the replication of several Enteroviruses with IC50 of 1.2 uM against coxsackievirus B3 replication, targets nonstructural protein 2C.. |
246148-68-5 |
DC11036 |
TCASK10
TCASK10 is a potent, highly specific inhibitor of ASK1 with IC50 of 14 nM, 30-fold selectivity over ASK2 (IC50=510 nM) and no activity against MEKK1, TAK1, IKKβ, ERK1, JNK1, p38α, GSK-3β, PKCθ and B-raf. |
1005775-56-3 |
DC7555 |
TC-DAPK-6
Featured
TC-DAPK 6 is an oxazalone compound that acts as a potent, ATP-competitive, and highly selective death-associated protein kinase (DAPK) inhibitor (IC50 = 69 and 225 nM against DAPK1 and DAPK3, respectively, with 10 uM ATP). |
315694-89-4 |
DC11125 |
TCH-165
Featured
TCH-165 is a specific small molecule modulator of proteasome assembly, regulates the dynamic equilibrium between the 20S and 26S proteasome complexes, favoring 20S-mediated protein degradation. |
1446350-60-2 |
DC23802 |
TCID
TCID is a selective ubiquitin C-terminal hydrolase-L3 (UCH-L3) inhibitor with IC50 of 0.6 uM, displays >100-fold selectivity over UCH-L1. |
30675-13-9 |
DC10178 |
TCN238
TCN238 is a positive allosteric mGlu4 receptor modulator with an EC50 of 1 μM. |
125404-04-8 |
DC23216 |
TCS 401
Featured
TCS 401 is a potent, selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B) with Ki of 0.29 uM, weakly inhibits the protein phosphatases CD45 D1D2, PTPβ, PTPε D1, SHP-1, PTPα D1, and LAR D1D2 with Ki of 59, 560, 1,100, >2,000, >2,000, and >2,000 u |
243966-09-8 |
DC21745 |
TD-6450
TD-6450 is a next generation, potent HCV NS5A inhibitor that has potent antiviral activity against HCV infection.. |
1374883-22-3 |
DC23751 |
TDI-2760
TDI-2760 si a small molecule Aβ-aggregation inhibitor that not only shows a strong inhibitory efficacy toward the Aβ-fibrinogen interaction (IC50=1.67 uM) but also retains potency toward the Aβ42 aggregation inhibition process. |
956128-08-8 |
DC2067 |
TDZD-8
Featured
TDZD-8 is a non-ATP competitive GSK-3β inhibitor with IC50 of 2 μM. |
327036-89-5 |
DC10331 |
Tebanicline hydrochloride
Tebanicline hydrochloride (ABT594 hydrochloride) is a nAChR modulator with potent, orally effective analgesic activity. It inhibits the binding of cytisine to α4β2 neuronal nAChRs with a Ki of 37 pM. |
203564-54-9 |
DC21552 |
Tecalcet
Tecalcet (R-568. |
148717-54-8 |
DC21553 |
Tecalcet hydrochloride
Tecalcet (R-568. |
177172-49-5 |
DC11026 |
Tecovirimat
Featured
Tecovirimat (ST-246, Tpoxx) is a potent, orally bioavailable, first-in-class inhibitor of orthopoxvirus egress with EC50 of 0.01-0.6 uM against a panel of Orthopoxviruses; ST-246 is active against multiple orthopoxviruses, including vaccinia, monkeypox, c |
869572-92-9 |
DC12603 |
TED-347
Featured
TED-347 (TED347) is an irreversible inhibitor of TEAD4-Yap1 protein-protein interaction (EC50=5.9 uM in FP asssays) via covalent modification of conserved cysteine (Cys367, Ki=1.3 uM), inhibits its binding to Yap1, blocked its transcriptional activity. |
2378626-29-8 |
DC9352 |
(S)-Tedizolid
Tedizolid is the active moiety of the prodrug tedizolid phosphate, with high potency against Gram-positive species. |
1431699-67-0 |
DC9315 |
Tegaserod (maleate)
Featured
Tegaserod maleate is a partial agonist of the 5-HT4 receptor; stimulates the peristaltic reflex and accelerates gastrointestinal transit. |
189188-57-6 |
DC9463 |
Tegobuvir (GS-9190; GS 333126)
Featured
Tegobuvir (GS-9190; GS 333126) is a non-nucleoside nonstructural protein (NS)5B polymerase inhibitor. |
1000787-75-6 |
DC20155 |
Tegoprazan
Featured
Tegoprazan, a potassium-competitive acid blocker, is a potent, oral active and highly selective inhibitor of gastric H+/K+-ATPase that could control gastric acid secretion and motility, with IC50 values ranging from 0.29-0.52 μM for porcine, canine, and human H+/K+-ATPases in vitro. |
942195-55-3 |
DC1008 |
Telaprevir (VX-950)
Featured
Telaprevir (VX-950) is an HCV NS3-4A serine protease inhibitor with IC50 of 0.35 μM. |
402957-28-2 |
DC4211 |
Telbivudine
Telbivudine (Tyzeka, Sebivo) is an antiviral agent used in the treatment of hepatitis B infection. |
3424-98-4 |