Cat. No. | Product name | CAS No. |
DC21469 |
Dagrocorat
Dagrocorat (PF 00251802) is a potent, selective high-affinity dissociated agonist of the glucocorticoid receptor.. |
1044535-52-5 |
DC23077 |
Daidzin
Featured
Daidzin is a potent, selective aldehyde dehydrogenase 2 (ALDH2,IC50 = 80 nM) inhibitor, which has antiallergic anti-oxidant, anti-carcinogenic, antithrombotic,and anti-atherosclerotic activities |
552-66-9 |
DC3163 |
Dalcetrapib (JTT-705)
Featured
Dalcetrapib (JTT-705) is a rhCETP inhibitor with IC50 of 0.2 μM. |
211513-37-0 |
DC22810 |
Damnacanthal
Damnacanthal is a highly potent, selective inhibitor of p56 lck tyrosine kinase with IC50 of 17 nM for inhibition of p56lck autophosphorylation. |
477-84-9 |
DC21881 |
Danicamtiv (MYK-491)
Featured
Danicamtiv (MYK-491), an inotropic agent, is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves mechanical efficiency. |
1970972-74-7 |
DCAPI1028 |
Danofloxacin Mesylate
Danofloxacin Mesylate |
119478-55-6 |
DC12338 |
Dansylamide
Dansyl amide is a fluorescent dye that is used in biochemistry and chemistry to label substances with the fluorescent dansyl group. |
1431-39-6 |
DC20170 |
Dapagliflozin propanediol monohydrate
Featured
Dapagliflozin propanediol belongs to the class of orally administered antidiabetic agents designated as sodiumglucose cotransporter 2 (SGLT2) inhibitors. |
960404-48-2 |
DC20941 |
DAPH-1
Featured
DAPH-1 (CGP 52411) is a small molecule that directly inhibits prion protein Sup35 prionogenesis with IC50 of 0.58 uM, inhibits and reverses the formation of Aβ42 fibers and reduces their toxicity to neurons in culture. |
145915-58-8 |
DC20354 |
DAPH-12
DAPH-12 is a small molecule that directly inhibits and reverses prion protein Sup35 prionogenesis (IC50=0.18 uM). |
145915-63-5 |
DC7395 |
Dapivirine
Featured
Dapivirine(TMC 120, TMC 120 R147681) is a NNRTI for HIV reverse transcriptase with IC50 of 24 nM, inhibits a broad panel of HIV-1 isolates from different classes, inclucing a wide range of NNRTI-resistant isolates. |
244767-67-7 |
DC10259 |
Dapson
Dapsone, also known as diaminodiphenyl sulfone (DDS), is an antibiotic commonly used in combination with rifampicin and clofazimine for the treatment of leprosy. |
80-08-0 |
DC1050 |
Daptomycin
Featured
Daptomycin is a lipopeptide antibiotic with rapid in vitro bactericidal activity against gram-positive organisms. |
103060-53-3 |
DCAPI1440 |
Darifenacin HBr
Darifenacin Hydrobromide is an antagonist of the M3 musarinnic acetylcholine receptor. |
133099-07-7 |
DC3152 |
Darifenacin
Darifenacin is a selective M3 muscarinic receptor antagonist with pKi of 8.9. |
133099-04-4 |
DC8647 |
DASA-58
Featured
DASA-58 is a highly specific small molecule PKM2 activator. DASA-58 inhibits LPS-induced Hif-1a and IL-1b, as well as the expression of a range of other Hif-1a-dependent genes. |
1203494-49-8 |
DC3140 |
Dasatinib monohydrate
Featured
Dasatinib is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. |
863127-77-9 |
DC21381 |
Dasolampanel
Dasolampanel (NGX426) is an orally bioavailable, competitive antagonist of the AMPA-kainate receptors for the treatment of chronic pain conditions including neuropathic pain and migraine.. |
503294-13-1 |
DC8162 |
Dasotraline(SEP-225289) free base
Featured
Dasotraline(SEP-225289) is a triple reuptake inhibitor that blocks dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respectively. |
675126-05-3 |
DC20229 |
Datelliptium chloride
Featured
Datelliptium chloride is a DNA-intercalating agent derived from ellipticine, with anti-tumor activities. |
105118-14-7 |
DC25058 |
Daunorubicin
Featured
Daunorubicin is potent topoisomerase II (Topo II) inhibitor, interacts with DNA by intercalation and inhibition of macromolecular biosynthesis in cancer cells. |
20830-81-3 |
DC20942 |
DB04760
DB04760 is a potent, highly selective, non–zinc-chelating MMP-13 inhibitor with IC50 of 8 nM, displays high selectivity over other MMPs. |
544678-85-5 |
DC8826 |
DB07268
Featured
DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM. |
929007-72-7 |
DC22067 |
DB1055
DB1055 (DB-1055, DB 1055) is a small molecule inhibitor of HOXA9/DNA interaction through binding as minor groove DNA ligand on the HOXA9 cognate sequence. |
869767-86-2 |
DC20943 |
DB2115
DB2115 is a small-molecule transcription factor PU.1 inhibitor abrogating DNA binding by PU.1 with Kd of 1.0 nM. |
1366231-70-0 |
DC23251 |
DB213
Featured
DB213 (RG-501) is a small molecule stimulator of HIV-1 frameshifting and inhibitor of viral replication. |
209163-39-3 |
DC12516 |
DB550
DB550 (DB-550) is a potent, peptidomimetic of calcium-inducing domain (CID) that disrupts the CD95-PLCγ1 interaction without affecting the CD95-FADD interaction binds to SH3-PLCγ1 with Kd of 40.7 uM. |
|
DC12517 |
HT105
DB550 (DB-550, TCWKHRK) is a potent, peptidomimetic of calcium-inducing domain (CID) that disrupts the CD95-PLCγ1 interaction, abrogates the CD95-mediated Ca2+ response in mouse PBLs with IC50 of 38 nM. |
|
DC22069 |
DB818
Featured
DB818 (DB-818, DB 818) is a small molecule inhibitor of HOXA9/DNA interaction through binding as minor groove DNA ligand on the HOXA9 cognate sequence. |
790241-43-9 |
DC21882 |
DBCO acid 1
DBCO acid 1 is a Click Chemistry intermidate used for antibody-drug conjugates.. |
1353016-70-2 |
DC21883 |
DBCO acid 2
DBCO acid 2 is a Click Chemistry intermidate used for antibody-drug conjugates.. |
1207355-31-4 |
DC21884 |
DBCO acid 3
DBCO acid 3 is a Click Chemistry intermidate used for antibody-drug conjugates.. |
1425485-72-8 |
DC21885 |
DBCO acid 4
DBCO acid 4 is a Click Chemistry intermidate used for antibody-drug conjugates.. |
1618102-42-3 |
DC21886 |
DBCO acid 5
DBCO acid 5 is a Click Chemistry intermidate used for antibody-drug conjugates.. |
1337920-25-8 |
DC21888 |
DBCO intermidate 1
DBCO intermidate 1 is a Click Chemistry intermidate used for antibody-drug conjugates.. |
23112-88-1 |
DC21889 |
DBCO intermidate 2
DBCO intermidate 2 is a Click Chemistry intermidate used for antibody-drug conjugates.. |
23194-93-6 |
DC21890 |
DBCO intermidate 3
Featured
DBCO intermidate 3 is a Click Chemistry intermidate used for antibody-drug conjugates.. |
1369862-03-2 |
DC21891 |
DBCO Maleimide
DBCO Maleimide is a Click Chemistry intermidate used for antibody-drug conjugates.. |
1395786-30-7 |
DC20355 |
DBCO-NHS ester 2
DBCO-NHS ester 2 is a derivative of DBCO (Dibenzylcyclooctyne) used in Cu-free click chemistry. |
1384870-47-6 |
DC22076 |
DBCO-NHS ester 3
DBCO-NHS ester 3 (DIBAC-NHS) is a Click Chemistry intermidate used for antibody-drug conjugates.. |
1393350-27-0 |
DC21987 |
DBCO-PEG4 amine
DBCO-PEG4 amine (ADIBO-PEG4-amine) is a Click Chemistry intermidate used for antibody-drug conjugates.. |
1255942-08-5 |
DC7602 |
DBeQ
Featured
DBeQ is a selective, potent, reversible, and ATP-competitive p97 inhibitor with IC50 of 1.5 μM. |
177355-84-9 |
DC21892 |
dBET23
dBET23 is a BRD4 heterobifunctional small-molecule ligand (PROTAC), exhibits significant and selective degradation of BRD4 BD1 (DC50/5h=50 nM) in cellular degradation assays.. |
1957234-83-1 |
DC21893 |
dBET57
Featured
dBET57 is a novel BRD4 heterobifunctional small-molecule ligand (PROTAC), exhibits significant and selective degradation of BRD4 BD1 (DC50/5h=500 nM), but is inactive on BRD4 BD2.. |
1883863-52-2 |
DC12665 |
DBPR114
Featured
DBPR114 is a quinazoline-based multi-kinase inhibitor for the treatment of acute myeloid leukemia and other solid tumors. |
|
DC23976 |
DC_517
DC_05 is a potent, selective, non-nucleoside DNA methyltransferase DNMT1 inhibitor with IC50 of 1.7 uM, displays significant selectivity toward other AdoMet-dependent protein methyltransferases. |
500017-70-9 |
DC23977 |
DC-05
Featured
DC-05 is a selective, non-nucleoside DNA methyltransferase DNMT1 inhibitor with IC50 of 10.3 uM, displays 3.6-fold selectivity over PRMT1 and >15-fold over DNMT3A, DNMT3B, G9a, SUV39H1, MLL1, SET7/9.. |
890643-16-0 |
DC20945 |
DC_AC50
Featured
DC_AC50 (DCAC50) is a small molecule that inhibits the human copper chaperones Atox1 and CCS (Kd=6.8 and 8.2 uM), blocks copper trafficking and significantly attenuates cancer cell proliferation. |
497061-48-0 |
DC12361 |
DC1
DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer. |
169901-27-3 |
DC12055 |
DC1-SMe
DC1-Sme is an antibody conjugate of phosphate prodrug of cytotoxic DNA alkylators for the targeted treatment of cancer. |
501666-85-9 |
DC12554 |
DC661
Featured
DC661 (DC-661) is a novel dimeric chloroquine (CQ) that is capable of deacidifying the lysosome and inhibiting autophagy significantly better than HCQ, targets palmitoyl-protein thioesterase 1 (PPT1). |
1872387-43-3 |
DC20175 |
Ripretinib (DCC-2618)
Featured
DCC-2618 is an orally bioavailable switch pocket control inhibitor of wild-type and mutated forms of the tumor-associated antigens (TAA) mast/stem cell factor receptor (SCFR) KIT and PDGFR-alpha, with IC50 values of 4 nM, 8 nM, 18 nM, 5 nM and 14 nM. |
1442472-39-0 |
DC24137 |
DCVC
DCVC (S-(1,2-dichlorovinyl)-L-cysteine) is an active metabolite of trichloroethylene. |
13419-46-0 |
DCAPI1304 |
D-Cycloserine
D-Cycloserine |
68-41-7 |
DC12593 |
DD-03-171
DD-03-171 is a small molecule, CGI1746-based BTK degrader (PROTAC, biochemical IC50=5.1 nM) that efficiently degrade C481S-BTK, exhibits enhanced anti-proliferative effects on mantle cell lymphoma (MCL) cells in vitro by degrading BTK, IKFZ1 and IKFZ3. |
|
DC20947 |
DDD 85646
Featured
DDD 85646 is a potent, specific, dual N-Myristoyltransferase NMT1/NMT2 inhibitor with IC50 of 17 nM/22 nM respectively. |
1215010-55-1 |
DC12521 |
DDR1 inhibitor 2.45
DDR1 inhibitor 2.45 (Compound 2.45) is a novel potent, selective, bioavailable Discoidin Domain Receptor 1 (DDR1) inhibitor with IC50 of 29 nM, displays 64-fold selectivity over DDR2 in biochemical assays. |
2125676-13-1 |
DC23844 |
DDR1 inhibitor 7rh
DDR1 inhibitor 7rh is a potent, selective, ATP-competitive, orally available Discoidin domain receptor 1 (DDR1) inhibitor with IC50 of 6.8 nM in cell-free kinase assays. |
1429617-90-2 |
DC7398 |
DDR1-IN-1
Featured
DDR1-IN-1 is a potent and selective DDR1 receptor tyrosine kinase inhibitor with IC50/EC50 of 105 nM/87 nM; 4-fold less potent for DDR2 (IC50= 413 nM). |
1449685-96-4 |
DC23857 |
DDR2-IN-5
DDR2-IN-5 is a potent, dual DDR2/SRC inhibitor with IC50 of 56/12 nM, potently suppresses DDR2 mutated cell lines HCC-366 and NCI-H2286 with IC50 of 0.44 uM and 0.29 uM.. |
1796592-06-7 |
DC12560 |
DDR-TRK-1
DDR-TRK-1 (DDR1 inhibitor 6j) is a potent, selective selective DDR1 inhibitor with IC50 of 9.4 nM, also potently inhibits TRK family with IC50 of 18-100 nM. |
1912357-12-0 |
DC4193 |
Decitabine
Featured
Decitabine is a potent inhibitor of DNA methylation with IC50 of 438 nM and 4.38 nM in HL-60 and KG1a cells, respectively. |
2353-33-5 |
DC12144 |
Decursin ((+)-Decursin)
Featured
Decursin is an anticancer agent, with potential anti-inflammatory activity. |
5928-25-6 |
DC10822 |
Defensamide(MHP)
Featured
Defensamide, also known as MHP and methyl caprooyl tyrosinate, is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production in KC. |
1104874-94-3 |
DCAPI1107 |
Deferasirox (Exjade)
Featured
Deferasirox (Exjade) |
201530-41-8 |
DC7399 |
Deferitrin
Featured
Deferitrin (GT-56-252) is the first drug in a class of desferrithiocin-derived hexadentate iron chelators. |
239101-33-8 |
DC11332 |
Degarelix (acetate)
Featured
Degarelix is a synthetic gonadotropin-releasing hormone receptor (GNRHR) antagonist (IC50 = 3 nM in HEK293 cells expressing the human receptor). |
214766-78-6 |
DC9337 |
Deguelin
Featured
Deguelin, a naturally occurring rotenoid, is known to be an Akt inhibitor and to have an anti-tumor effect on several cancers; decrease levels of phosphorylated Akt. |
522-17-8 |
DC5201 |
Dehydroepiandrosterone (DHEA)
Dehydroepiandrosterone(DHEA) is a 19-carbon endogenous natural steroid hormone. |
53-43-0 |
DC23727 |
Dehydromutactin
Dehydromutactin is a small molecule inhibitor of RNA-binding protein Hu protein R (HuR) that interferes the HuR homodimerization with Kd of 40 nM. |
823803-77-6 |
DC12073 |
Dehydronitrosonisoldipine
Dehydronitrosonisoldipine is a calcium channel antagonist. |
87375-91-5 |
DC10458 |
Delafloxacin(ABT-492)
Featured
Delafloxacin (RX-3341, ABT-492) is a fluoroquinolone antibiotic agent. |
189279-58-1 |
DC20116 |
Delafloxacin meglumine (ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine)
Featured
Delafloxacin meglumine (ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and |
352458-37-8 |
DC20772 |
Deleobuvir
Deleobuvir (BI-207127, BI207127) is a potent, selective HCV NS5B polymerase inhibitor with IC50 of 50 nM against GT-1 HCV polymerase activity. |
863884-77-9 |
DC20948 |
Deltasonamide 2
Deltasonamide 2 (Deltasonamide-2) is a novel small molecule inhibitor of PDE6δ/KRas interaction with Kd of 385 pM. |
2088485-34-9 |
DC26004 |
delta-Valerobetaine (hydrobromide)
Featured
Delta-Valerobetaine (hydrobromide) is a precursor of trimethylamine N-oxide (TMAO). |
66258-96-6 |
DC12287 |
delta-Valerobetaine
Featured
Delta-Valerobetaine is a precursor of trimethylamine N-oxide (TMAO). |
6778-33-2 |
DC20949 |
Deltazinone 1
Deltazinone 1 (Deltazinone1) is a novel highly selective PDEδ inhibitor that inhibits PDEδ/Ras interaction with Kd of 8±4 nM. |
894554-89-3 |
DC10850 |
Dencichine
Dencichin is a non-protein amino acid originally extracted from Panax notoginseng, and can inhibit HIF-prolyl hydroxylase-2 (PHD-2) activity. |
5302-45-4 |
DC7199 |
Denibulin (MN-029)
Denibulin (MN-029) is a novel vascular-disrupting agent that reversibly inhibits microtubule assembly, resulting in disruption of the cytoskeleton of tumor vascular endothelial cells. |
779356-64-8 |
DC8712 |
Deoxycorticosterone acetate
Featured
Deoxycorticosterone acetate is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as a precursor to aldosterone. |
56-47-3 |
DC10308 |
Deoxycytidine triphosphate
Deoxycytidine triphosphate (dCTP), a nucleoside triphosphate, is a raw material in DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing. |
2056-98-6 |
DC21402 |
Deoxynyboquinone
Deoxynyboquinone, also known as DNQ, is a potent inducer of cancer cell death. DNQ potently induces death of cancer cells in culture, with IC(50) values between 16 and 210 nM. In addition, unlike the experimental therapeutic elesclomol, DNQ is still able to induce cancer cell death under hypoxic conditions. This mechanistic understanding of DNQ will allow for a more comprehensive evaluation of the potential of direct ROS generation as an anticancer strategy, and DNQ itself has potential as a novel anticancer agent. |
96748-86-6 |
DC23791 |
Deoxyspergualin
Deoxyspergualin is a derivative of the antitumor antibiotic spergualin that binds specifically to Hsc70, also inhibits poly(rC) binding protein 2 (PCBP2).. |
98629-43-7 |
DC24197 |
Derenofylline(SLV320)
Featured
Derenofylline(SLV320) is a potent and selective adenosine A1 receptor antagonist (Ki values are 1, 200, 398 and 3981 nM at human A1, A3, A2A and A2B receptors respectively). |
251945-92-3 |
DC11055 |
Desmethyl dabrafenib
Featured
Desmethyl dabrafenib (GSK2167542, Dabrafenib metabolite M8) is the desmethyl- metabolic byproduct of Dabrafenib, ameliorates developmental pathologies of Kabuki Syndrome in vivo.. |
1195765-47-9 |
DCAPI1287 |
Desonide
Desonide |
638-94-8 |
DC11331 |
Desoximetasone
Desoximetasone is a glucocorticoid. |
382-67-2 |
DC9631 |
Desvenlafaxine (succinate hydrate)
Desvenlafaxine succinate hydrate is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI). |
386750-22-7 |
DC20273 |
Deuterated AZ5104
Featured
Deuterated AZ5104 is a potent EGFR inhibitor. |
2129998-32-7 |
DCAPI1025 |
Dexamethasone
Featured
Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs used as an anti-inflammatory and immunosuppressant. |
50-02-2 |
DC10231 |
D panthenol
Dexpanthenol is an alcoholic analogue of D-pantothenic acid and cholinergic agent. |
81-13-0 |
DCAPI1475 |
Dexrazoxane Hydrochloride
Dexrazoxane Hydrochloride |
149003-01-0 |
DCAPI1431 |
Dextromethorphan hydrobromide
Dextromethorphan hydrobromide |
125-69-9 |
DC9093 |
Dextromethorphan HBr
Dextromethorphan hydrobromide hydrate is an antitussive drug. |
6700-34-1 |
DC23104 |
D-Fagomine
D-Fagomine (Fagomine) is a a mild glycosidase inhibitor, inhibits Amyloglucosidase (A.niger), β-Glucosidase (bovine), and Isomaltase (yeast) with Ki of 4.8 uM, 39 uM, and 70 uM, respectively. |
53185-12-9 |
DC22187 |
DFMO
DFMO (Ornithine Decarboxylase inhibitor DFMO) is an irreversible inhibitor of ornithine decarboxylase (ODC), inhibits polyamine biosynthesis. |
68278-23-9 |
DC22074 |
DFP00173
Featured
DFP00173 (DFP-00173) is a potent and selective aquaporin-3 (AQP3) inhibitor, inhibits glycerol permeability in erythrocytes with IC50 of 0.2 uM.. |
672286-03-2 |
DC24079 |
DG-172 dihydrochloride
Featured
DG-172 is a novel PPARβ/δ-selective ligand showing high binding affinity (IC50= 27 nM) and potent inverse agonistic properties. |
1361504-77-9 |
DC20357 |
D-G23
D-G23 is a small molecule that inhibits RAD52-mediated ssDNA annealing with IC50 of 5.8 uM, binds to RAD52 with Kd of 34 uM and inhibits D-loop formation with IC50 of 7.2 uM in vitro. |
1225141-73-0 |
DC23686 |
DGAT1-IN-1
DGAT1-IN-1 is a potent DGAT1 inhibitor with IC50 of < 10 nM.. |
1449779-49-0 |
DC20358 |
DGAT2 inhibitor 2
DGAT2 inhibitor 2 is a novel potent, selective DGAT2 inhibitor with IC50 of 6 nM (hDGAT2), shows no significant activity for DGAT1 (IC50>20 uM). |
|
DCAPI1274 |
D-glutamine
D-glutamine is a D type stereoisomer of glutamine which is one of the 20 amino acids encoded by the standard genetic code. |
5959-95-5 |
DC20953 |
DH-376
DH-376 is a highly potent dual DAGLα/β inhibitor with IC50 of 6 nM and 3-8 nM, respectively. |
1848233-57-7 |
DC20937 |
D-I03
D-I03 (D-103) is a small molecule that inhibits RAD52-mediated ssDNA annealing with IC50 of 5 uM, binds to RAD52 with Kd of 25.8 uM and inhibits D-loop formation with IC50 of 8 uM in vitro. |
688342-78-1 |
DC20954 |
DI-404
DI-404 is a highly potent, peptidomimetic inhibitor of DCN1-UBC12 protein-protein interaction that bind to DCN1 protein with Kd of 6.9 nM, selectively inhibits the neddylation of cullin 3 over other cullin members. |
|
DC23201 |
Diarylpropionitrile
Featured
Diarylpropionitrile (DPN) is a non-steroidal estrogen receptor β(ERβ) selective ligand, demonstrates the neuroprotective effects against 10 0M Aβ1-42-induced oxidative stress and inflammation in primary rat cortical cell culture. |
1428-67-7 |
DC23747 |
Diazepinomicin
Diazepinomicin (TLN 4601. |
733035-26-2 |
DC20153 |
Dibutyl phthalate
Featured
Dibutyl phthalate is a commonly used plasticizer commonly found in some food packaging materials, personal care products, and the coating of oral medications. May cause toxicity and adverse neurobehavioral effects. |
84-74-2 |
DC8394 |
Dibutyryl-cAMP (Bucladesine)
Featured
Dibutyryl-cAMP (Bucladesine) is a cell-permeable PKA activator by mimicing the action of endogenous cAMP. |
16980-89-5 |
DCAPI1032 |
Dichlorphenamide (Diclofenamide)
Featured
Dichlorphenamide (Diclofenamide) |
120-97-8 |
DC8918 |
Diclazepam
Diclazepam(Ro5-3448; Chlorodiazepam) is an analogue of diazepam; are similar to diazepam, possessing anxiolytic, anticonvulsant, hypnotic, sedative, skeletal muscle relaxant, and amnestic properties. |
2894-68-0 |
DC20359 |
Dicycloplatin
Dicycloplatin (DCP) is a novel platinum analog that demonstrates significant antitumor activity against a variety of human cancer cell lines with IC50 of 25-30 nM. |
287402-09-9 |
DC9481 |
Didanosine
Didanosine(Videx) is a reverse transcriptase inhibitor with an IC50 of 0.49 μM. Target: NRTIs; HIV Didanosine is a dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. |
69655-05-6 |
DC22178 |
Didemethylclomipramine
Didemethylclomipramine (Norclomipramine, N-Desmethylcomipramine) is the major active metabolite of the tricyclic antidepressant (TCA) clomipramine. |
303-48-0 |
DC9890 |
Diethyl maleate
Diethylmaleate is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NFkB. |
141-05-9 |
DC12140 |
Diethyl-pythiDC
Diethyl-pythiDC is an inhibitor of collagen prolyl 4-hydroxylases (CP4Hs). |
1821370-70-0 |
DC21445 |
Difamilast
Featured
Difamilast (OPA-15406) is a novel potent, selective phosphodiesterase IV (PDE4) inhibitor with preference for PDE4B (IC50=11.2 nM). |
937782-05-3 |
DC10256 |
Diflunisal
Diflunisal is a difluorophenyl derivate of salicylic acid and a nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic and anti-inflammatory properties. The mechanism of action of diflunisal is as a Cyclooxygenase Inhibitor. |
22494-42-4 |
DC9551 |
Difluprednate
Featured
Difluprednate(Durezol) is a corticosteroid, approved difluprednate for the treatment of post-operative ocular inflammation and pain. |
23674-86-4 |
DC12167 |
Digitonin
Featured
Digitonin, a glycoside obtained from Digitalis purpurea, could increase cell permeability by binding to cholesterol molecules and reduce tumor growth. |
11024-24-1 |
DC9760 |
Dihexa (PNB-0408)
Featured
Dihexa is an oligopeptide drug that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met. |
1401708-83-5 |
DC23085 |
Dihydrocapsaicin
Dihydrocapsaicin, a potential inducer of autophagy, has cytotoxic activity. It has anti-atherogenic activity, can reduce the susceptibility of low-density lipoprotein (LDL) to oxidation. Dihydrocapsaicin treatment depletes peptidergic nerve fibers of subs |
19408-84-5 |
DC8274 |
Dihydroethidium
Featured
Dihydroethidium(Hydroethidine; PD-MY 003) is a superoxide indicator; exhibits blue-fluorescence in the cytosol until oxidized, where it intercalates within the cell's DNA, staining its nucleus a bright fluorescent red. |
104821-25-2 |
DC10176 |
Dihydroisotanshinone I
Dihydroisotanshinone I is a bioactive compound present in a widely used traditional Chinese medicine named danshen. |
20958-18-3 |
DC11961 |
Dihydromunduletone
Dihydromunduletone is a rotenoid derivative that selectively inhibits GPR56 (IC50=21 uM) and GPR114/ADGRG5, but not GPR110 or Class A GPCRs. |
674786-20-0 |
DC20362 |
DIMATE
DIMATE is a novel irreversible, competitive, isoform-specific ALDH1 inhibitor, displays cytotoxic activity on human AML cell lines with IC50 of 1-15 uM. |
350229-29-7 |
DC20223 |
DIM-C-pPhCO2Me
Featured
DIM-C-pPhCO2Me is a nuclear receptor 4A1 (NR4A1) antagonist with antineoplastic activity. |
151358-48-4 |
DC10791 |
DIM-C-pPhOH(CDIM8)
Featured
DIM-C-pPhOH is a Nur77 Antagonist. DIM-C-pPhOH inhibits lung cancer cell and tumor growth in a metastasis model. |
151358-47-3 |
DC10262 |
5,5-Dimethyloxazolidine-2,4-dione
Dimethadione is an anticonvulsant that is the active metabolite of trimethadione. |
3166-62-9 |
DC7402 |
Dimethocaine
Dimethocaine, a synthetic cocaine derivative: studies on its in vitro metabolism catalyzed by P450s and NAT2.For the detailed information of Dimethocaine, the solubility of Dimethocaine in water, the solubility of Dimethocaine in DMSO, the solubility of Dimethocaine in PBS buffer, the animal experiment (test) of Dimethocaine, the cell expriment (test) of Dimethocaine, the in vivo, in vitro and clinical trial test of Dimethocaine, the EC50, IC50,and Affinity of Dimethocaine, Please contact DC Chemicals.. |
94-15-5 |
DC8722 |
Dimethoxycurcumin(DiMC)
Featured
Dimethoxycurcumin is an analog of curcumin obtained by methylation of both free phenolic groups in the parent compound. |
160096-59-3 |
DC20147 |
Dimethyl 4-hydroxyisophthalate
Featured
Dimethyl 4-hydroxyisophthalate is a methyl salicylate analogue. |
5985-24-0 |
DC24169 |
Dimethyl fumarate
Dimethyl fumarate (DMF. |
624-49-7 |
DC23590 |
Diminazene aceturate
Diminazene aceturate is an anti-infective agent, also is a slow pore blocker of acid-sensing ion channel 1a (ASIC1a) with IC50 of 0.3 uM. |
908-54-3 |
DC8588 |
Diminutol
Diminutol is a cell-permeable 2,6,9-trisubstituted purine analog that blocks mitotic spindle assembly by competitively inhibiting NQO1, an NADP-dependent oxidoreductase. |
361431-33-6 |
DC8674 |
Diniconazole
Diniconazole is a newly developed fungicide strongly inhibited lanosterol 14 alpha-demethylation catalyzed by a yeast cytochrome P-450. |
83657-24-3 |
DC23155 |
Dinoprost tromethamine salt
Featured
Dinoprost (Prostaglandin F2α, PGF2α) is a naturally occurring prostaglandin used to induce labor and as an abortifacient, causes contraction of vascular, bronchial, intestinal, and myometrial smooth muscle, and also exhibits potent luteolytic activity.. |
38562-01-5 |
DC8707 |
Dinotefuran
Dinotefuran is an insecticide of the neonicotinoid class, its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors. |
165252-70-0 |
DC9834 |
Dioscin
Featured
Dioscin(CCRIS 4123; Collettiside III) is a natural steroid saponin derived from several plants, showing potent anti-cancer effect against a variety of tumor cell lines. |
19057-60-4 |
DC10243 |
2,2′-Dihydroxy-4-methoxybenzophenone
Dioxybenzone (benzophenone-8) is an organic compound used in sunscreen to block UVB and short-wave UVA (ultraviolet) rays |
131-53-3 |
DC26047 |
Dipeptide diaminobutyroyl benzylamide (acetate)
Featured
Dipeptide diaminobutyroyl benzylamide is a biomimetic peptide and a muscarinic acetylcholine receptor antagonist. |
823202-99-9 |
DCAPI1582 |
Diphenhydramine Citrate
Diphenhydramine Citrate |
88637-37-0 |
DCAPI1072 |
Diphenhydramine HCl (Benadryl)
Diphenhydramine HCl (Benadryl) |
147-24-0 |
DC23591 |
Diphyllin
Diphyllin is a naturally potent vacuolar ATPase (v-ATPase) inhibitor with IC50 of 17 nM, potently inhibits the acid influx with IC50 of 0.6 nM. |
22055-22-7 |
DC12269 |
Diprotin A TFA (Ile-Pro-Pro (TFA))
Diprotin A (TFA) is an inhibitor of dipeptidyl peptidase IV (DPP-IV). |
209248-71-5 |
DC26059 |
Diprotin A
Featured
Diprotin A is a tripeptide inhibitor of dipeptidyl peptidase 4 |
90614-48-5 |
DC11244 |
Diprovocim
Diprovocim is a potent human and mouse Toll-like receptor (TLR)1/TLR2 agonist. |
2170867-89-5 |
DCAPI1267 |
Dipyridamole (Persantine)
Dipyridamole (Persantine) |
58-32-2 |
DC10343 |
Diquafosol tetrasodium
Featured
Diquafosol tetrasodium is a P2Y2 receptor agonist that stimulates fluid and mucin secretion on the ocular surface, as a topical treatment of dry eye disease. |
211427-08-6 |
DC23302 |
Disarib
Featured
Disarib is a novel BCL2-specific inhibitor that binds predominantly to the BH1 domain, demonstrates strong affinity to BCL2, but not to other antiapoptotic BCL2 family members(BCL-xL, BCL2A1 etc.). |
1998149-15-7 |
DC22511 |
Disitertide
Disitertide (P144) is a TGF-β1 antagonist peptide. |
272105-42-7 |
DCAPI1398 |
Disulfiram (Antabuse)
Featured
Disulfiram (Antabuse) |
97-77-8 |
DCAPI1335 |
Divalproex sodium
Divalproex sodium |
76584-70-8 |
DC23122 |
DiZPK
Featured
DiZPK is a genetically encoded, highly efficient photocrosslinking amino acid valuable in unveiling the physiological interaction partners of given proteins and their functions.. |
1337883-32-5 |
DC22216 |
DJ4
Featured
DJ4 (ROCK inhibitor DJ4) is a potent, selective, ATP-competitive inhibitor of ROCK1/2 and MRCKα/β with IC50 of 5/50 nM and 10/100 nM, respectively. |
1681020-24-5 |
DC12040 |
DJ-V-159
Featured
DJ-V-159 is an agonist for G protein-coupled receptor family C group 6 member A (GPRC6A). |
2253744-53-3 |
DC12442 |
DK419
Featured
DK419 (DK-419) a potent, orally acitve inhibitor of Wnt/β-catenin signaling with IC50 of 0.19 uM in Wnt3A-stimulated TOPFlash assays. |
2102672-22-8 |
DC12431 |
DKFZ-251
DKFZ-251 (DKFZ251) is a selective inhibitor of Kallikrein-related peptidase 6 (KLK6) with IC50 of 0.13 uM, demonstrates good selectivity for KLK6 compared to other KLKs. |
2222059-70-1 |
DC12404 |
DKFZ-633
DKFZ-633 (DKFZ633) is a selective inhibitor of Kallikrein-related peptidase 6 (KLK6) with IC50 of 0.25 uM, demonstrates good selectivity for KLK6 compared to other KLKs. |
2244425-14-5 |
DC10550 |
DKM 2-93
Featured
DKM 2-93 is a relatively selective inhibitor of UBA5 with an IC50 of 430 μM. |
65836-72-8 |
DC10707 |
DL-AP4
Featured
DL-AP4 is a Broad spectrum EAA antagonist. |
6323-99-5 |
DC20363 |
DL-AP4 sodium salt
DL-AP4 sodium salt is a broad spectrum glutamate receptor antagonist.. |
1263093-79-3 |
DC10708 |
DL-AP5
Featured
DL-AP5 is a Broad spectrum EAA antagonist. |
76326-31-3 |
DC10709 |
DL-AP5 Sodium salt
Featured
DL-AP5 is a Broad spectrum EAA antagonist. |
1303993-72-7 |
DCAPI1183 |
DL-Carnitine HCl
DL-Carnitine HCl |
461-05-2 |
DC11486 |
D-Luciferin (potassium salt)
Featured
D-Luciferin is a chemiluminescent substrate of firefly luciferase. |
115144-35-9 |
DC9287 |
D-Luciferin
Featured
D-Luciferin is a popular bioluminescent substrate of luciferase in the presence of ATP, used in luciferase-based bioluminescence imaging and cell-based high-throughput screening applications. Cas: 2591-17-5 |
2591-17-5 |
DC11426 |
DM1-PEG4-DBCO
Featured
DM1-(PEG)4-DBCO (DBCO-PEG4-DM1) is made by DM1 conjugated to DBCO-(PEG)4 linker.DM1 (mertansine), a thiol-containing maytansinoid, is a potent microtubule-disrupting agent. |
|
DC11396 |
DM1-SMe
Featured
DM1-SMe is a potent maytansinoid microtubular inhibitor and an unconjugated DM1 as a mixed disulfide with thiomethane to cap its sulfhydryl group. |
138148-68-2 |
DC9401 |
DMAT(CK2 Inhibitor)
Featured
DMAT is a potent and specific CK2 inhibitor with an IC50 of 0.13 uM. |
749234-11-5 |
DC7403 |
Dimethyloxaloylglycine(DMOG)
Featured
DMOG is a cell permeable prolyl-4-hydroxylase inhibitor, which upregulates HIF (hypoxia-inducible factor). |
89464-63-1 |
DC20600 |
DM-PIT-1
Featured
DM-PIT-1 is a specific PIP3 antagonist that disrupts PIP3/Akt PH domain, PIP3/PDK1 PH domain, and PIP3/GRP1 PH domain with IC50 of 27.1 uM, 80.5 uM, and 35.5 uM, respectively. |
701947-53-7 |
DC22291 |
DMU-212(resveratrol analog)
Featured
DMU-212, a methoxylated resveratrol analog, has significant anticancer activity, and selectively targets tumor cells. |
134029-62-2 |
DC22307 |
DMX-5804
Featured
DMX-5804 is a potent, orally active and selective MAP4K4 inhibitor, with an IC50 of 3 nM, a pIC50 of 8.55 for human MAP4K4, less potent on MINK1/MAP4K6 (pIC50, 8.18), and TNIK/MAP4K7 (pIC50, 7.96). |
2306178-56-1 |
DC20959 |
DNDI-8219
DNDI-8219 is a novel potent, orally active antileishmanial agent with IC50 of 0.19 uM against Leishmania donovani (L. don). |
2222660-40-2 |
DC23671 |
DNMDP
DNMDP is a potent and selective cancer cell cytotoxic agent that binds to PDE3A, promotes an interaction between PDE3A and Schlafen 12 (SLFN12). |
328104-79-6 |
DC21509 |
DNS-pE
DNS-pE (PHGDH Fluorescent Probe DNS-pE) is the first small molecule that can selectively label endogenous 3-phosphoglycerate dehydrogenase (PHGDH) from various mammalian cells. |
|
DC20364 |
DNS-pE2
DNS-pE2 is the first small molecule that can selectively label endogenous 3-phosphoglycerate dehydrogenase (PHGDH) from various mammalian cells. |
|
DC20136 |
DO34 analog
DO34 analog is a triazole DAGL(α) inhibitor extracted from patent WO2017096315 A1, compound 100. |
2098969-71-0 |
DC20960 |
DO-34
DO-34 is a highly potent dual DAGLα/β inhibitor with IC50 of 6 nM 3-8 nM, respectively. |
1848233-58-8 |
DC8416 |
Docetaxel Trihydrate
Docetaxel, an analog of paclitaxel, is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules. |
148408-66-6 |
DC4187 |
Docetaxel
Featured
Docetaxel, an analog of taxol, is an inhibitor of depolymerisation of microtubules through binding to stabilized microtubules. |
114977-28-5 |
DCAPI1299 |
Docosanol (Abreva)
Docosanol (Abreva) |
661-19-8 |
DC12208 |
Docosapentaenoic acid 22n-3
Docosapentaenoic acid (22n-3) is a component of phospholipids found in all animal cell membranes. |
24880-45-3 |
DC10247 |
Docusate Sodium
Docusate Sodium is a laxative used to treat constipation, for constipation due to the use of opiates it maybe used with a stimulant laxative, can be taken by mouth or rectally. |
577-11-7 |
DC9648 |
Dodecanoic acid ingenol ester
Featured
Dodecanoic acid ingenol ester is a natural compound. |
54706-70-6 |
DC12216 |
Dodecanoylcarnitine
Featured
Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease. |
25518-54-1 |
DCAPI1022 |
Dofetilide (Tikosyn)
Featured
Dofetilide (Tikosyn) |
115256-11-6 |
DC9133 |
Domperidone
Domperidone is a dopamine blocker and an antidopaminergic reagent. |
57808-66-9 |
DCAPI1164 |
Doripenem Hydrate
Doripenem Hydrate |
364622-82-2 |
DC20365 |
Dorrigocin A
Dorrigocin A is a natural compound that shows potent antiproliferative effect on tumor cell line.. |
158446-29-8 |
DC4219 |
Dorzolomide hydrochloride
Dorzolamide HCl is a carbonic anhydrase inhibitor. |
130693-82-2 |
DC20057 |
Dot1L-IN-1
Dot1L-IN-1 is a highly potent, selective and structurally novel Dot1L inhibitor with a Ki of 2 pM. |
2088518-50-5 |
DC21895 |
DOTA-ADIBO
DOTA-ADIBO is a Click Chemistry intermidate used for antibody-drug conjugates.. |
1374865-01-6 |
DC3142 |
Dovitinib Dilacticacid
Featured
Dovitinib (TKI258, CHIR-258) is a multitargeted tyrosine kinase inhibitor of FLT3 and c-KIT with IC50 of 1 nM and 2 nM, respectively. |
852433-84-2 |
DC9597 |
Doxapram (hydrochloride hydrate)
Doxapram hydrochloride hydrate inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively. |
7081-53-0 |
DC9664 |
Doxapram
Featured
Doxapram inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively. |
309-29-5 |
DC9061 |
Doxepin HCl
Doxepin HCl is a tricyclic antidepressant that is marketed worldwide. |
1229-29-4 |
DC8994 |
Doxifluridine/5-Fluoro-5′-deoxyuridine
Doxifluridine(Ro 21-9738; 5'-DFUR) is a thymidine phosphorylase activator for PC9-DPE2 cells with IC50 of 0.62 μM. |
3094-09-5 |